| 1 |
RA CAPITAL MANAGEMENT, L.P. |
2,670,300 |
10,254,000 |
25.36% |
|
|
| 2 |
SABBY MANAGEMENT, LLC |
2,350,567 |
9,026,000 |
22.32% |
|
|
| 3 |
Broadfin Capital, LLC |
1,968,631 |
7,560,000 |
18.70% |
|
|
| 4 |
GREAT POINT PARTNERS LLC |
1,108,593 |
4,257,000 |
10.53% |
|
|
| 5 |
VANGUARD GROUP INC |
950,244 |
3,649,000 |
9.02% |
|
|
| 6 |
Opaleye Management Inc. |
440,000 |
1,690,000 |
4.18% |
|
|
| 7 |
Opus Point Partners Management, LLC |
248,854 |
956,000 |
2.36% |
|
|
| 8 |
DEUTSCHE BANK AG\ |
145,000 |
556,000 |
1.38% |
|
|
| 9 |
Bank of New York Mellon Corp |
125,247 |
481,000 |
1.19% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
80,411 |
308,000 |
0.76% |
|
|
| 11 |
BlackRock Fund Advisors |
69,011 |
265,000 |
0.66% |
|
|
| 12 |
D. E. Shaw & Co., Inc. |
64,096 |
246,000 |
0.61% |
|
|
| 13 |
MORGAN STANLEY |
46,952 |
180,000 |
0.45% |
|
|
| 14 |
Verition Fund Management LLC |
46,175 |
177,000 |
0.44% |
|
|
| 15 |
AXA S.A. |
42,702 |
164,000 |
0.41% |
|
|
| 16 |
GOLDMAN SACHS GROUP INC |
35,347 |
136,000 |
0.34% |
|
|
| 17 |
BlackRock Institutional Trust Company, N.A. |
31,830 |
122,000 |
0.30% |
|
|
| 18 |
NORTHERN TRUST CORP |
30,385 |
117,000 |
0.29% |
|
|
| 19 |
MILLENNIUM MANAGEMENT LLC |
24,500 |
94,000 |
0.23% |
|
|
| 20 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
12,031 |
46,000 |
0.11% |
|
|
| 21 |
Alpine Global Management, LLC |
11,123 |
43,000 |
0.11% |
|
|
| 22 |
FIRST NEW YORK SECURITIES LLC /NY |
10,000 |
38,400 |
0.09% |
|
|
| 23 |
UBS Group AG |
4,907 |
19,000 |
0.05% |
|
|
| 24 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,300 |
16,512 |
0.04% |
|
|
| 25 |
BlackRock Investment Management, LLC |
4,048 |
16,000 |
0.04% |
|
|
| 26 |
CITIGROUP INC |
2,000 |
8,000 |
0.02% |
|
|
| 27 |
Tower Research Capital LLC (TRC) |
986 |
4,000 |
0.01% |
|
|
| 28 |
Karp Capital Management Corp |
700 |
3,000 |
0.01% |
|
|
| 29 |
ROYAL BANK OF CANADA |
459 |
2,000 |
0.00% |
|
|
| 30 |
BANK OF MONTREAL /CAN/ |
400 |
2,000 |
0.00% |
|
|
| 31 |
Hudock, Inc. |
6 |
0 |
0.00% |
|
|
| 32 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
1 |
0 |
0.00% |
|
|
| 33 |
North Star Investment Management Corp. |
17 |
0 |
0.00% |
|
|
| 34 |
WELLS FARGO & COMPANY/MN |
3 |
0 |
0.00% |
|
|
| 35 |
BANK OF AMERICA CORP /DE/ |
72 |
0 |
0.00% |
|
|
| 36 |
HUNTINGTON NATIONAL BANK |
13 |
0 |
0.00% |
|
|
