| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SANGAMO BIOSCIENCES INCORPORATED | 6,000,000 | 91,620,000 | 9.85% | Call | |
| 2 | BIOCRYST PHARMACEUTICALS | 7,050,356 | 85,732,000 | 9.21% | ||
| 3 | ACHILLION PHARMACEUTICALS INC COM | 6,700,000 | 82,075,000 | 8.82% | ||
| 4 | REGULUS THERAPEUTICS INC | 4,742,911 | 76,076,000 | 8.18% | ||
| 5 | DYAX CORP COM CVR | 4,945,697 | 69,536,000 | 7.47% | ||
| 6 | TG THERAPEUTICS INC COM | 3,350,449 | 53,071,000 | 5.70% | ||
| 7 | BLUEBIRD BIO INCORPORATED | 506,122 | 46,422,000 | 4.99% | ||
| 8 | Dicerna Pharmaceuticals | 2,428,571 | 39,999,000 | 4.30% | ||
| 9 | ACADIA PHARMACEUTICALS INC COM | 1,000,000 | 31,750,000 | 3.41% | Call | |
| 10 | ACHILLION PHARMACEUTICALS INC COM | 2,500,000 | 30,625,000 | 3.29% | Call | |
| 11 | COHERUS BIOSCIENCES INC COM | 1,555,355 | 25,383,000 | 2.73% | ||
| 12 | ZS PHARMA INC | 564,483 | 23,466,000 | 2.52% | ||
| 13 | ZAFGEN INC COM | 732,960 | 22,604,000 | 2.43% | ||
| 14 | XENCOR INC COM | 1,399,423 | 22,447,000 | 2.41% | ||
| 15 | FORWARD PHARMA A/S | 970,600 | 20,218,000 | 2.17% | ||
| 16 | NOVAVAX INC COM | 3,241,083 | 19,220,000 | 2.07% | ||
| 17 | SANGAMO BIOSCIENCES INCORPORATED | 1,220,209 | 18,559,000 | 1.99% | ||
| 18 | TREVENA INC | 2,974,647 | 17,788,000 | 1.91% | ||
| 19 | JUNO THERAPEUTICS INCORPORATED | 280,000 | 14,622,000 | 1.57% | ||
| 20 | THERAPEUTICSMD INC | 3,211,132 | 14,290,000 | 1.54% | ||
| 21 | OPHTHOTECH CORP COM | 310,554 | 13,935,000 | 1.50% | ||
| 22 | Proteon Therapeutics | 1,250,000 | 13,000,000 | 1.40% | ||
| 23 | TENAX THERAPEUTICS INC COM | 2,670,300 | 10,254,000 | 1.10% | ||
| 24 | BELLICUM PHARMACEUTICALS INC COM | 1,026,402 | 9,337,000 | 1.00% | ||
| 25 | AURINIA PHARMACEUTICALS INC | 2,474,076 | 9,006,000 | 0.97% | ||
| 26 | SCYNEXIS INC | 840,000 | 8,383,000 | 0.90% | ||
| 27 | ROCKWELL MED INC COM | 706,252 | 7,260,000 | 0.78% | ||
| 28 | AKEBIA THERAPEUTICS INC | 597,363 | 6,953,000 | 0.75% | ||
| 29 | Vical Inc | 6,203,690 | 6,514,000 | 0.70% | ||
| 30 | CTI BIOPHARMA CORP | 2,500,000 | 5,900,000 | 0.63% | ||
| 31 | VERSARTIS INC COM | 231,267 | 5,192,000 | 0.56% | ||
| 32 | AURIS MED HLDG AG | 940,000 | 3,666,000 | 0.39% | ||
| 33 | BIOTA PHARMACEUTIALS INC COM | 1,378,770 | 3,088,000 | 0.33% | ||
| 34 | OCERA THERAPEUTICS INC | 417,476 | 2,659,000 | 0.29% | ||
| 35 | T2 BIOSYSTEMS INC | 138,002 | 2,655,000 | 0.29% | ||
| 36 | AGIOS PHARMACEUTICALS INC | 17,600 | 1,972,000 | 0.21% | ||
| 37 | WAFERGEN BIO-SYSTEMS INC | 560,000 | 1,680,000 | 0.18% | ||
| 38 | PTC THERAPEUTICS INC | 25,800 | 1,336,000 | 0.14% | ||
| 39 | SANOFI SPOND FUNSPONSORED ADR | 116,400 | 1,315,000 | 0.14% | ||
| 40 | NEWLINK GENETICS CORP | 30,000 | 1,193,000 | 0.13% | ||
| 41 | ALKERMES PLC SHS | 19,200 | 1,124,000 | 0.12% | ||
| 42 | REGENERON PHARMACEUTICALS | 2,450 | 1,005,000 | 0.11% | ||
| 43 | CELGENE CORP | 8,700 | 973,000 | 0.10% | ||
| 44 | AMGEN INC | 5,900 | 940,000 | 0.10% | ||
| 45 | REPLIGEN CORP COM | 45,000 | 891,000 | 0.10% | ||
| 46 | BIOGEN INC | 2,600 | 883,000 | 0.09% | ||
| 47 | ACADIA PHARMACEUTICALS INC COM | 27,300 | 867,000 | 0.09% | ||
| 48 | KERYX BIOPHARMACEUTICALS INCORPORATED | 59,200 | 838,000 | 0.09% | ||
| 49 | CELLADON CORP | 40,900 | 799,000 | 0.09% | ||
| 50 | KYTHERA BIOPHARMACEUTICALS I | 22,750 | 789,000 | 0.08% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-010101, filed 2015.02.17).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
