| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,587,215 | 8,408,000 | 23.06% | ||
| 2 | EVENTIDE ASSET MANAGEMENT, LLC | 2,719,410 | 7,826,000 | 21.46% | ||
| 3 | Clarus Ventures, LLC | 2,121,212 | 6,894,000 | 18.90% | ||
| 4 | Omega Fund Management, LLC | 1,696,969 | 5,515,000 | 15.12% | ||
| 5 | AWM Investment Company, Inc. | 1,696,968 | 5,515,000 | 15.12% | ||
| 6 | ACUTA CAPITAL PARTNERS, LLC | 467,333 | 1,524,000 | 4.18% | ||
| 7 | DAFNA Capital Management LLC | 202,496 | 662,000 | 1.82% | ||
| 8 | BOXER CAPITAL, LLC | 28,100 | 91,000 | 0.25% | ||
| 9 | ROYAL BANK OF CANADA | 4,200 | 14,000 | 0.04% | ||
| 10 | MORGAN STANLEY | 3,658 | 12,000 | 0.03% | ||
| 11 | Tower Research Capital LLC (TRC) | 1,381 | 4,000 | 0.01% | ||
| 12 | BANK OF MONTREAL /CAN/ | 1,000 | 3,000 | 0.01% | ||
| 13 | Evercore Wealth Management, LLC | 5,670 | 0 | 0.00% | ||
| 14 | TORONTO DOMINION BANK | 80 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
