| 1 |
PERCEPTIVE ADVISORS LLC |
1,762,881 |
5,923,000 |
22.88% |
|
|
| 2 |
SOROS FUND MANAGEMENT LLC |
1,462,122 |
4,913,000 |
18.98% |
|
|
| 3 |
Knoll Capital Management, LLC |
1,359,767 |
4,569,000 |
17.65% |
|
|
| 4 |
SPHERA FUNDS MANAGEMENT LTD. |
600,000 |
2,016,000 |
7.79% |
|
|
| 5 |
VANGUARD GROUP INC |
534,397 |
1,796,000 |
6.94% |
|
|
| 6 |
SABBY MANAGEMENT, LLC |
300,000 |
1,008,000 |
3.89% |
|
|
| 7 |
ROYCE & ASSOCIATES LP |
299,643 |
1,007,000 |
3.89% |
|
|
| 8 |
BlackRock Fund Advisors |
278,528 |
936,000 |
3.62% |
|
|
| 9 |
DAFNA Capital Management LLC |
181,818 |
611,000 |
2.36% |
|
|
| 10 |
BlackRock Institutional Trust Company, N.A. |
142,403 |
478,000 |
1.85% |
|
|
| 11 |
GLG Partners LP |
129,128 |
434,000 |
1.68% |
|
|
| 12 |
NORTHERN TRUST CORP |
104,785 |
352,000 |
1.36% |
|
|
| 13 |
CAMBRIDGE TRUST CO |
65,414 |
220,000 |
0.85% |
|
|
| 14 |
STATE STREET CORP |
65,430 |
219,000 |
0.85% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
60,414 |
202,000 |
0.78% |
|
|
| 16 |
BlackRock Investment Management, LLC |
44,444 |
149,000 |
0.58% |
|
|
| 17 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
40,765 |
137,000 |
0.53% |
|
|
| 18 |
PRELUDE CAPITAL MANAGEMENT, LLC |
30,000 |
101,000 |
0.39% |
|
|
| 19 |
IFP ADVISORS, INC |
25,004 |
84,000 |
0.32% |
|
|
| 20 |
GOLDMAN SACHS GROUP INC |
22,221 |
75,000 |
0.29% |
|
|
| 21 |
Numeric Investors LLC |
21,460 |
72,000 |
0.28% |
|
|
| 22 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
21,070 |
71,000 |
0.27% |
|
|
| 23 |
TEACHERS ADVISORS, LLC |
19,764 |
66,000 |
0.25% |
|
|
| 24 |
ALLIANCEBERNSTEIN L.P. |
15,500 |
63,000 |
0.24% |
|
|
| 25 |
Bank of New York Mellon Corp |
18,652 |
63,000 |
0.24% |
|
|
| 26 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
14,621 |
50,000 |
0.19% |
|
|
| 27 |
D. E. Shaw & Co., Inc. |
13,007 |
44,000 |
0.17% |
|
|
| 28 |
RHUMBLINE ADVISERS |
12,263 |
41,000 |
0.16% |
|
|
| 29 |
MORGAN STANLEY |
11,648 |
39,000 |
0.15% |
|
|
| 30 |
NEW YORK STATE COMMON RETIREMENT FUND |
9,400 |
32,000 |
0.12% |
|
|
| 31 |
Nationwide Fund Advisors |
6,593 |
22,000 |
0.08% |
|
|
| 32 |
AMERICAN INTERNATIONAL GROUP, INC. |
6,051 |
20,000 |
0.08% |
|
|
| 33 |
Tower Research Capital LLC (TRC) |
5,601 |
19,000 |
0.07% |
|
|
| 34 |
CITIGROUP INC |
3,484 |
12,000 |
0.05% |
|
|
| 35 |
BLACKROCK ADVISORS LLC |
2,801 |
9,000 |
0.03% |
|
|
| 36 |
DEUTSCHE BANK AG\ |
2,826 |
9,000 |
0.03% |
|
|
| 37 |
Creative Planning |
2,400 |
8,000 |
0.03% |
|
|
| 38 |
BANK OF AMERICA CORP /DE/ |
2,302 |
8,000 |
0.03% |
|
|
| 39 |
BNP PARIBAS FINANCIAL MARKETS |
1,044 |
3,508 |
0.01% |
|
|
| 40 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
1,000 |
3,000 |
0.01% |
|
|
| 41 |
UBS Group AG |
567 |
2,000 |
0.01% |
|
|
| 42 |
WELLS FARGO & COMPANY/MN |
320 |
1,000 |
0.00% |
|
|
| 43 |
CUTLER GROUP LLC / CA |
500 |
1,000 |
0.00% |
|
|
| 44 |
WHITTIER TRUST CO |
1 |
0 |
0.00% |
|
|
| 45 |
PIERSHALE FINANCIAL GROUP, INC. |
5 |
0 |
0.00% |
|
|
| 46 |
ROYAL BANK OF CANADA |
1 |
0 |
0.00% |
|
|
| 47 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
131 |
0 |
0.00% |
|
|
