| 1 |
PERCEPTIVE ADVISORS LLC |
1,762,881 |
4,159,000 |
26.43% |
|
|
| 2 |
SOROS FUND MANAGEMENT LLC |
1,462,122 |
3,451,000 |
21.93% |
|
|
| 3 |
Knoll Capital Management, LLC |
1,359,767 |
3,209,000 |
20.40% |
|
|
| 4 |
VANGUARD GROUP INC |
540,300 |
1,275,000 |
8.10% |
|
|
| 5 |
ROYCE & ASSOCIATES LP |
376,321 |
888,000 |
5.64% |
|
|
| 6 |
SABBY MANAGEMENT, LLC |
270,000 |
637,000 |
4.05% |
|
|
| 7 |
DAFNA Capital Management LLC |
181,818 |
429,000 |
2.73% |
|
|
| 8 |
SPHERA FUNDS MANAGEMENT LTD. |
138,105 |
326,000 |
2.07% |
|
|
| 9 |
NEXTHERA CAPITAL LP |
100,000 |
236,000 |
1.50% |
|
|
| 10 |
BlackRock Institutional Trust Company, N.A. |
70,687 |
167,000 |
1.06% |
|
|
| 11 |
CAMBRIDGE TRUST CO |
65,414 |
154,000 |
0.98% |
|
|
| 12 |
GEODE CAPITAL MANAGEMENT, LLC |
61,087 |
144,000 |
0.92% |
|
|
| 13 |
MILLENNIUM MANAGEMENT LLC |
58,823 |
139,000 |
0.88% |
|
|
| 14 |
Paloma Partners Management Co |
41,993 |
99,000 |
0.63% |
|
|
| 15 |
BlackRock Fund Advisors |
36,662 |
87,000 |
0.55% |
|
|
| 16 |
PRELUDE CAPITAL MANAGEMENT, LLC |
30,000 |
71,000 |
0.45% |
|
|
| 17 |
IFP ADVISORS, INC |
25,004 |
59,000 |
0.37% |
|
|
| 18 |
GOLDMAN SACHS GROUP INC |
17,545 |
41,000 |
0.26% |
|
|
| 19 |
NORTHERN TRUST CORP |
15,884 |
37,000 |
0.24% |
|
|
| 20 |
CREDIT SUISSE AG/ |
14,343 |
33,000 |
0.21% |
|
|
| 21 |
DEUTSCHE BANK AG\ |
13,035 |
30,000 |
0.19% |
|
|
| 22 |
MORGAN STANLEY |
6,337 |
15,000 |
0.10% |
|
|
| 23 |
BANK OF AMERICA CORP /DE/ |
5,726 |
14,000 |
0.09% |
|
|
| 24 |
WEALTHPLAN PARTNERS, LLC |
15,036 |
10,982 |
0.07% |
|
|
| 25 |
BlackRock Investment Management, LLC |
2,643 |
6,000 |
0.04% |
|
|
| 26 |
Creative Planning |
2,400 |
6,000 |
0.04% |
|
|
| 27 |
Hartford Financial Management Inc. |
2,300 |
5,000 |
0.03% |
|
|
| 28 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
663 |
2,000 |
0.01% |
|
|
| 29 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
1,000 |
2,000 |
0.01% |
|
|
| 30 |
JPMORGAN CHASE & CO |
464 |
1,000 |
0.01% |
|
|
| 31 |
Tower Research Capital LLC (TRC) |
497 |
1,000 |
0.01% |
|
|
| 32 |
CUTLER GROUP LLC / CA |
300 |
0 |
0.00% |
|
|
| 33 |
WHITTIER TRUST CO |
1 |
0 |
0.00% |
|
|
| 34 |
PIERSHALE FINANCIAL GROUP, INC. |
5 |
0 |
0.00% |
|
|
| 35 |
UBS Group AG |
1 |
0 |
0.00% |
|
|
| 36 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
131 |
0 |
0.00% |
|
|
| 37 |
CITIGROUP INC |
200 |
0 |
0.00% |
|
|
| 38 |
BARCLAYS PLC |
196 |
0 |
0.00% |
|
|
| 39 |
WELLS FARGO & COMPANY/MN |
200 |
0 |
0.00% |
|
|
| 40 |
ADVISOR GROUP, INC. |
1 |
0 |
0.00% |
|
|
