| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,896,284 | 158,618,000 | 43.06% | ||
| 2 | FEDERATED HERMES, INC. | 1,101,730 | 44,851,000 | 12.18% | ||
| 3 | GILDER GAGNON HOWE & CO LLC | 585,870 | 23,851,000 | 6.48% | ||
| 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 526,460 | 21,433,000 | 5.82% | ||
| 5 | ORBIMED ADVISORS LLC | 512,900 | 20,880,000 | 5.67% | ||
| 6 | DEERFIELD MANAGEMENT COMPANY, L.P. | 441,085 | 17,957,000 | 4.88% | ||
| 7 | BAKER BROS. ADVISORS LP | 369,276 | 15,033,000 | 4.08% | ||
| 8 | WELLINGTON MANAGEMENT GROUP LLP | 337,083 | 13,723,000 | 3.73% | ||
| 9 | GOLDMAN SACHS GROUP INC | 333,374 | 13,572,000 | 3.68% | ||
| 10 | Rock Springs Capital Management LP | 210,000 | 8,549,000 | 2.32% | ||
| 11 | Zweig-DiMenna Associates LLC | 171,840 | 6,996,000 | 1.90% | ||
| 12 | RS INVESTMENT MANAGEMENT CO LLC | 97,182 | 3,956,000 | 1.07% | ||
| 13 | MORGAN STANLEY | 81,621 | 3,322,000 | 0.90% | ||
| 14 | Atika Capital Management LLC | 65,500 | 2,666,000 | 0.72% | ||
| 15 | GRATICULE ASIA MACRO ADVISORS LLC | 50,000 | 2,036,000 | 0.55% | ||
| 16 | OLD MISSION CAPITAL LLC | 42,473 | 1,729,000 | 0.47% | ||
| 17 | BANK OF AMERICA CORP /DE/ | 38,239 | 1,556,000 | 0.42% | ||
| 18 | JANE STREET GROUP, LLC | 25,984 | 1,058,000 | 0.29% | ||
| 19 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 25,192 | 1,025,000 | 0.28% | ||
| 20 | MACQUARIE GROUP LTD | 23,581 | 960,000 | 0.26% | ||
| 21 | Weiss Multi-Strategy Advisers LLC | 20,500 | 835,000 | 0.23% | ||
| 22 | Tekla Capital Management LLC | 20,000 | 814,000 | 0.22% | ||
| 23 | Rail-Splitter Capital Management, LLC | 13,164 | 536,000 | 0.15% | ||
| 24 | NAVELLIER & ASSOCIATES INC | 11,780 | 480,000 | 0.13% | ||
| 25 | GLG Partners LP | 11,684 | 476,000 | 0.13% | ||
| 26 | DEUTSCHE BANK AG\ | 10,000 | 407,000 | 0.11% | ||
| 27 | NOMURA ASSET MANAGEMENT CO LTD | 10,000 | 407,000 | 0.11% | ||
| 28 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 6,000 | 244,000 | 0.07% | ||
| 29 | UBS Group AG | 3,410 | 139,000 | 0.04% | ||
| 30 | DAFNA Capital Management LLC | 1,709 | 70,000 | 0.02% | ||
| 31 | BANK OF MONTREAL /CAN/ | 1,500 | 61,000 | 0.02% | ||
| 32 | Creative Planning | 1,300 | 53,000 | 0.01% | ||
| 33 | Walleye Trading LLC | 500 | 20,000 | 0.01% | ||
| 34 | ROYAL BANK OF CANADA | 420 | 17,000 | 0.00% | ||
| 35 | Tower Research Capital LLC (TRC) | 219 | 9,000 | 0.00% | ||
| 36 | Edge Wealth Management LLC | 200 | 8,000 | 0.00% | ||
| 37 | CITIGROUP INC | 19 | 1,000 | 0.00% | ||
| 38 | BNP PARIBAS FINANCIAL MARKETS | 2 | 81 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
