| 1 |
BRIDGER MANAGEMENT, LLC |
5,204,618 |
31,540,000 |
17.58% |
|
|
| 2 |
FMR LLC |
4,859,764 |
29,450,000 |
16.42% |
|
|
| 3 |
RA CAPITAL MANAGEMENT, L.P. |
4,531,714 |
27,462,000 |
15.31% |
|
|
| 4 |
BAKER BROS. ADVISORS LP |
2,003,991 |
12,144,000 |
6.77% |
|
|
| 5 |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
1,810,844 |
10,974,000 |
6.12% |
|
|
| 6 |
PICTET ASSET MANAGEMENT LTD |
1,215,449 |
9,140,000 |
5.10% |
|
|
| 7 |
VANGUARD GROUP INC |
1,484,133 |
8,995,000 |
5.01% |
|
|
| 8 |
BlackRock Fund Advisors |
968,987 |
5,872,000 |
3.27% |
|
|
| 9 |
BlackRock Institutional Trust Company, N.A. |
899,739 |
5,452,000 |
3.04% |
|
|
| 10 |
STATE STREET CORP |
624,307 |
3,783,000 |
2.11% |
|
|
| 11 |
COLUMBUS CIRCLE INVESTORS |
577,769 |
3,501,000 |
1.95% |
|
|
| 12 |
EVENTIDE ASSET MANAGEMENT, LLC |
537,600 |
3,258,000 |
1.82% |
|
|
| 13 |
NORTHERN TRUST CORP |
460,288 |
2,789,000 |
1.55% |
|
|
| 14 |
STONERIDGE INVESTMENT PARTNERS LLC |
295,482 |
1,791,000 |
1.00% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
277,277 |
1,680,000 |
0.94% |
|
|
| 16 |
NEW YORK STATE COMMON RETIREMENT FUND |
223,851 |
1,357,000 |
0.76% |
|
|
| 17 |
MILLENNIUM MANAGEMENT LLC |
198,298 |
1,202,000 |
0.67% |
|
|
| 18 |
CREDIT SUISSE AG/ |
192,336 |
1,166,000 |
0.65% |
|
|
| 19 |
Bank of New York Mellon Corp |
176,637 |
1,070,000 |
0.60% |
|
|
| 20 |
Opaleye Management Inc. |
175,000 |
1,061,000 |
0.59% |
|
|
| 21 |
Candriam S.C.A. |
170,000 |
1,030,000 |
0.57% |
|
|
| 22 |
GUGGENHEIM CAPITAL LLC |
164,213 |
995,000 |
0.55% |
|
|
| 23 |
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY |
160,700 |
974,000 |
0.54% |
|
|
| 24 |
BlackRock Investment Management, LLC |
149,087 |
903,000 |
0.50% |
|
|
| 25 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
124,800 |
756,000 |
0.42% |
|
|
| 26 |
CREDIT SUISSE AG/ |
116,900 |
708,000 |
0.39% |
Put |
|
| 27 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
115,728 |
701,000 |
0.39% |
|
|
| 28 |
Nationwide Fund Advisors |
108,904 |
660,000 |
0.37% |
|
|
| 29 |
A.R.T. Advisors, LLC |
88,654 |
537,000 |
0.30% |
|
|
| 30 |
OXFORD ASSET MANAGEMENT LLP |
78,427 |
475,000 |
0.26% |
|
|
| 31 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
77,235 |
468,000 |
0.26% |
|
|
| 32 |
FRED ALGER MANAGEMENT, LLC |
68,100 |
413,000 |
0.23% |
|
|
| 33 |
Swiss National Bank |
66,600 |
404,000 |
0.23% |
|
|
| 34 |
DEUTSCHE BANK AG\ |
65,776 |
397,000 |
0.22% |
|
|
| 35 |
ALLIANCEBERNSTEIN L.P. |
61,240 |
371,000 |
0.21% |
|
|
| 36 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
59,050 |
358,000 |
0.20% |
|
|
| 37 |
TEACHERS ADVISORS, LLC |
56,545 |
343,000 |
0.19% |
|
|
| 38 |
MORGAN STANLEY |
50,882 |
309,000 |
0.17% |
|
|
| 39 |
CITADEL ADVISORS LLC |
44,001 |
267,000 |
0.15% |
|
|
| 40 |
Trexquant Investment LP |
43,609 |
264,000 |
0.15% |
|
|
| 41 |
Virtu KCG Holdings LLC |
43,326 |
263,000 |
0.15% |
|
|
| 42 |
ROYAL LONDON ASSET MANAGEMENT LTD |
43,133 |
261,000 |
0.15% |
|
|
| 43 |
RHUMBLINE ADVISERS |
37,547 |
228,000 |
0.13% |
|
|
| 44 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
35,500 |
215,000 |
0.12% |
Put |
|
| 45 |
VIRTUS ETF ADVISERS LLC |
35,297 |
214,000 |
0.12% |
|
|
| 46 |
Creative Planning |
32,147 |
195,000 |
0.11% |
|
|
| 47 |
EMERALD ACQUISITION LTD. |
31,272 |
190,000 |
0.11% |
|
|
| 48 |
SECOR Capital Advisors, LP |
30,820 |
187,000 |
0.10% |
|
|
| 49 |
Weiss Multi-Strategy Advisers LLC |
30,600 |
185,000 |
0.10% |
|
|
| 50 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
30,023 |
182,000 |
0.10% |
|
|
