| 1 |
TPG Group Holdings (SBS) Advisors, Inc. |
3,551,929 |
34,312,000 |
37.63% |
|
|
| 2 |
EVENTIDE ASSET MANAGEMENT, LLC |
1,384,100 |
13,370,000 |
14.66% |
|
|
| 3 |
CLOUGH CAPITAL PARTNERS L P |
1,016,878 |
9,823,000 |
10.77% |
|
|
| 4 |
GREAT POINT PARTNERS LLC |
554,426 |
5,356,000 |
5.87% |
|
|
| 5 |
First Light Asset Management, LLC |
393,926 |
3,805,000 |
4.17% |
|
|
| 6 |
WALL STREET ASSOCIATES |
366,700 |
3,542,000 |
3.88% |
|
|
| 7 |
GENERAL ELECTRIC CO |
264,550 |
2,556,000 |
2.80% |
|
|
| 8 |
MILLENNIUM MANAGEMENT LLC |
230,333 |
2,225,000 |
2.44% |
|
|
| 9 |
I.G. INVESTMENT MANAGEMENT, LTD. |
209,648 |
2,025,000 |
2.22% |
|
|
| 10 |
Skylands Capital, LLC |
198,463 |
1,917,000 |
2.10% |
|
|
| 11 |
FEDERATED HERMES, INC. |
176,400 |
1,704,000 |
1.87% |
|
|
| 12 |
VANGUARD GROUP INC |
154,914 |
1,496,000 |
1.64% |
|
|
| 13 |
GILDER GAGNON HOWE & CO LLC |
130,184 |
1,258,000 |
1.38% |
|
|
| 14 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
148,600 |
1,195,000 |
1.31% |
|
|
| 15 |
Cormorant Asset Management, LP |
100,200 |
968,000 |
1.06% |
|
|
| 16 |
Weiss Multi-Strategy Advisers LLC |
70,000 |
676,000 |
0.74% |
|
|
| 17 |
NORTHERN TRUST CORP |
69,936 |
676,000 |
0.74% |
|
|
| 18 |
Pine River Capital Management L.P. |
57,023 |
551,000 |
0.60% |
|
|
| 19 |
STATE STREET CORP |
54,876 |
530,000 |
0.58% |
|
|
| 20 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
41,000 |
396,000 |
0.43% |
|
|
| 21 |
ACUTA CAPITAL PARTNERS, LLC |
29,024 |
280,000 |
0.31% |
|
|
| 22 |
PIPER SANDLER & CO. |
25,250 |
244,000 |
0.27% |
|
|
| 23 |
Bank of New York Mellon Corp |
25,222 |
244,000 |
0.27% |
|
|
| 24 |
GEODE CAPITAL MANAGEMENT, LLC |
24,343 |
235,000 |
0.26% |
|
|
| 25 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
22,315 |
216,000 |
0.24% |
|
|
| 26 |
MORGAN STANLEY |
20,306 |
196,000 |
0.21% |
|
|
| 27 |
Clearbridge Investments, LLC |
18,780 |
181,000 |
0.20% |
|
|
| 28 |
KOPP INVESTMENT ADVISORS LLC |
17,210 |
166,000 |
0.18% |
|
|
| 29 |
BOGLE INVESTMENT MANAGEMENT L P /DE/ |
16,106 |
155,000 |
0.17% |
|
|
| 30 |
TFS CAPITAL LLC |
13,001 |
126,000 |
0.14% |
|
|
| 31 |
A.R.T. Advisors, LLC |
13,107 |
126,000 |
0.14% |
|
|
| 32 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
12,019 |
116,000 |
0.13% |
|
|
| 33 |
HARBOURVEST PARTNERS LLC |
11,101 |
107,000 |
0.12% |
|
|
| 34 |
HighTower Advisors, LLC |
10,937 |
106,000 |
0.12% |
|
|
| 35 |
TEACHERS ADVISORS, LLC |
8,851 |
86,000 |
0.09% |
|
|
| 36 |
Nationwide Fund Advisors |
4,926 |
48,000 |
0.05% |
|
|
| 37 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,086 |
39,471 |
0.04% |
|
|
| 38 |
DEUTSCHE BANK AG\ |
3,803 |
36,000 |
0.04% |
|
|
| 39 |
PANAGORA ASSET MANAGEMENT INC |
2,264 |
22,000 |
0.02% |
|
|
| 40 |
STRS OHIO |
2,000 |
19,000 |
0.02% |
|
|
| 41 |
CITIGROUP INC |
1,596 |
16,000 |
0.02% |
|
|
| 42 |
UBS Group AG |
675 |
7,000 |
0.01% |
|
|
| 43 |
ALLIANCEBERNSTEIN L.P. |
500 |
5,000 |
0.01% |
|
|
| 44 |
BANK OF AMERICA CORP /DE/ |
500 |
5,000 |
0.01% |
|
|
| 45 |
BARCLAYS PLC |
370 |
3,000 |
0.00% |
|
|
| 46 |
WELLS FARGO & COMPANY/MN |
301 |
3,000 |
0.00% |
|
|
| 47 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
168 |
2,000 |
0.00% |
|
|
| 48 |
ROYAL BANK OF CANADA |
52 |
1,000 |
0.00% |
|
|
