| 1 |
FMR LLC |
16,245,530 |
12,212,000 |
32.60% |
|
|
| 2 |
BlackRock Fund Advisors |
4,076,625 |
3,064,000 |
8.18% |
|
|
| 3 |
VANGUARD GROUP INC |
3,732,512 |
2,806,000 |
7.49% |
|
|
| 4 |
Opaleye Management Inc. |
2,950,000 |
2,218,000 |
5.92% |
|
|
| 5 |
BlackRock Institutional Trust Company, N.A. |
2,776,125 |
2,087,000 |
5.57% |
|
|
| 6 |
SENZAR ASSET MANAGEMENT, LLC |
2,327,100 |
1,749,281 |
4.67% |
|
|
| 7 |
D. E. Shaw & Co., Inc. |
2,232,069 |
1,678,000 |
4.48% |
|
|
| 8 |
JPMORGAN CHASE & CO |
2,227,550 |
1,674,000 |
4.47% |
|
|
| 9 |
STATE STREET CORP |
1,284,362 |
961,000 |
2.57% |
|
|
| 10 |
NORTHERN TRUST CORP |
967,524 |
728,000 |
1.94% |
|
|
| 11 |
Palo Alto Investors LP |
799,000 |
601,000 |
1.60% |
|
|
| 12 |
TWO SIGMA ADVISERS, LP |
732,600 |
569,000 |
1.52% |
|
|
| 13 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
653,394 |
491,000 |
1.31% |
|
|
| 14 |
GEODE CAPITAL MANAGEMENT, LLC |
584,189 |
439,000 |
1.17% |
|
|
| 15 |
MACQUARIE GROUP LTD |
500,000 |
376,000 |
1.00% |
|
|
| 16 |
Nationwide Fund Advisors |
499,258 |
375,000 |
1.00% |
|
|
| 17 |
Jefferies Group LLC |
499,974 |
375,000 |
1.00% |
|
|
| 18 |
CITADEL ADVISORS LLC |
421,934 |
317,000 |
0.85% |
|
|
| 19 |
Bank of New York Mellon Corp |
408,399 |
307,000 |
0.82% |
|
|
| 20 |
Artal Group S.A. |
400,000 |
301,000 |
0.80% |
Call |
|
| 21 |
TWO SIGMA INVESTMENTS, LP |
368,160 |
277,000 |
0.74% |
|
|
| 22 |
Granite Point Capital Management, L.P. |
360,824 |
271,000 |
0.72% |
|
|
| 23 |
BlackRock Investment Management, LLC |
322,759 |
243,000 |
0.65% |
|
|
| 24 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
273,600 |
206,000 |
0.55% |
|
|
| 25 |
WEDBUSH SECURITIES INC |
270,480 |
203,000 |
0.54% |
|
|
| 26 |
BELLEVUE ASSET MANAGEMENT AG |
225,000 |
169,000 |
0.45% |
|
|
| 27 |
CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. |
175,200 |
132,000 |
0.35% |
|
|
| 28 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
165,888 |
125,000 |
0.33% |
|
|
| 29 |
GROUP ONE TRADING LLC |
165,211 |
124,000 |
0.33% |
|
|
| 30 |
MILLENNIUM MANAGEMENT LLC |
156,349 |
118,000 |
0.31% |
|
|
| 31 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
150,400 |
114,000 |
0.30% |
|
|
| 32 |
Swiss National Bank |
150,100 |
113,000 |
0.30% |
|
|
| 33 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
130,200 |
98,000 |
0.26% |
Put |
|
| 34 |
GOLDMAN SACHS GROUP INC |
130,139 |
98,000 |
0.26% |
|
|
| 35 |
ROYAL BANK OF CANADA |
129,280 |
97,000 |
0.26% |
|
|
| 36 |
CANADA LIFE ASSURANCE Co |
117,100 |
88,000 |
0.23% |
|
|
| 37 |
JANE STREET GROUP, LLC |
115,638 |
87,000 |
0.23% |
|
|
| 38 |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
111,600 |
84,000 |
0.22% |
|
|
| 39 |
ProShare Advisors LLC |
99,143 |
75,000 |
0.20% |
|
|
| 40 |
ALLIANCEBERNSTEIN L.P. |
98,500 |
74,000 |
0.20% |
|
|
| 41 |
BLACKROCK ADVISORS LLC |
93,194 |
70,000 |
0.19% |
|
|
| 42 |
RHUMBLINE ADVISERS |
90,131 |
68,000 |
0.18% |
|
|
| 43 |
CREDIT SUISSE AG/ |
90,296 |
68,000 |
0.18% |
|
|
| 44 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
88,700 |
67,000 |
0.18% |
Call |
|
| 45 |
PRELUDE CAPITAL MANAGEMENT, LLC |
83,800 |
63,000 |
0.17% |
|
|
| 46 |
MORGAN STANLEY |
82,857 |
63,000 |
0.17% |
|
|
| 47 |
NEW YORK STATE COMMON RETIREMENT FUND |
83,000 |
62,000 |
0.17% |
|
|
| 48 |
AMERICAN INTERNATIONAL GROUP, INC. |
76,010 |
57,000 |
0.15% |
|
|
| 49 |
Creative Planning |
67,639 |
51,000 |
0.14% |
|
|
| 50 |
TUDOR INVESTMENT CORP ET AL |
64,225 |
48,000 |
0.13% |
|
|
