| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SC XII MANAGEMENT LLC | 7,744,460 | 84,105,000 | 24.33% | ||
| 2 | Capital World Investors | 4,222,609 | 45,858,000 | 13.27% | ||
| 3 | JENNISON ASSOCIATES LLC | 2,356,346 | 25,590,000 | 7.40% | ||
| 4 | VANGUARD GROUP INC | 2,261,052 | 24,555,000 | 7.10% | ||
| 5 | BlackRock Finance, Inc. | 1,699,447 | 18,455,000 | 5.34% | ||
| 6 | SOFINNOVA MANAGEMENT VIII, L.L.C. | 1,550,280 | 16,836,000 | 4.87% | ||
| 7 | ORBIMED ADVISORS LLC | 1,276,190 | 13,859,000 | 4.01% | ||
| 8 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1,072,610 | 11,649,000 | 3.37% | ||
| 9 | MACQUARIE GROUP LTD | 1,061,880 | 11,532,000 | 3.34% | ||
| 10 | FRANKLIN RESOURCES INC | 1,042,325 | 11,320,000 | 3.28% | ||
| 11 | Bank of New York Mellon Corp | 634,743 | 6,893,000 | 1.99% | ||
| 12 | BROADVIEW ADVISORS LLC | 505,500 | 5,490,000 | 1.59% | ||
| 13 | Tekla Capital Management LLC | 485,758 | 5,275,000 | 1.53% | ||
| 14 | Contrarius Investment Management Ltd | 480,944 | 5,223,000 | 1.51% | ||
| 15 | RENAISSANCE TECHNOLOGIES LLC | 458,900 | 4,984,000 | 1.44% | ||
| 16 | STATE STREET CORP | 448,708 | 4,875,000 | 1.41% | ||
| 17 | KORNITZER CAPITAL MANAGEMENT INC /KS | 436,290 | 4,738,000 | 1.37% | ||
| 18 | NORTHERN TRUST CORP | 352,808 | 3,831,000 | 1.11% | ||
| 19 | Polar Asset Management Partners Inc. | 267,281 | 2,903,000 | 0.84% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 258,110 | 2,803,000 | 0.81% | ||
| 21 | MORGAN STANLEY | 234,740 | 2,549,000 | 0.74% | ||
| 22 | BAKER BROS. ADVISORS LP | 228,676 | 2,483,000 | 0.72% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 219,223 | 2,381,000 | 0.69% | ||
| 24 | WADDELL & REED FINANCIAL INC | 215,766 | 2,343,000 | 0.68% | ||
| 25 | Spark Investment Management LLC | 214,000 | 2,324,000 | 0.67% | ||
| 26 | D. E. Shaw & Co., Inc. | 166,304 | 1,806,000 | 0.52% | ||
| 27 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 150,000 | 1,629,000 | 0.47% | ||
| 28 | SECOR Capital Advisors, LP | 133,627 | 1,451,000 | 0.42% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 123,534 | 1,342,000 | 0.39% | ||
| 30 | PRINCIPAL FINANCIAL GROUP INC | 112,687 | 1,224,000 | 0.35% | ||
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 109,594 | 1,191,000 | 0.34% | ||
| 32 | PRICE T ROWE ASSOCIATES INC /MD/ | 103,875 | 1,128,000 | 0.33% | ||
| 33 | CITADEL ADVISORS LLC | 93,194 | 1,012,000 | 0.29% | ||
| 34 | BANK OF AMERICA CORP /DE/ | 77,630 | 844,000 | 0.24% | ||
| 35 | ASYMMETRY CAPITAL MANAGEMENT, L.P. | 63,811 | 693,000 | 0.20% | ||
| 36 | STRS OHIO | 60,800 | 660,000 | 0.19% | ||
| 37 | Capital Impact Advisors, LLC | 60,212 | 654,000 | 0.19% | ||
| 38 | PDT Partners, LLC | 57,900 | 629,000 | 0.18% | ||
| 39 | DEUTSCHE BANK AG\ | 56,188 | 608,000 | 0.18% | ||
| 40 | TEACHERS ADVISORS, LLC | 55,907 | 607,000 | 0.18% | ||
| 41 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 55,589 | 604,000 | 0.17% | ||
| 42 | HighTower Advisors, LLC | 50,115 | 544,000 | 0.16% | ||
| 43 | Swiss National Bank | 42,300 | 459,000 | 0.13% | ||
| 44 | PRUDENTIAL FINANCIAL INC | 42,120 | 457,000 | 0.13% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 35,400 | 384,000 | 0.11% | ||
| 46 | RHUMBLINE ADVISERS | 34,533 | 375,000 | 0.11% | ||
| 47 | PRELUDE CAPITAL MANAGEMENT, LLC | 34,121 | 371,000 | 0.11% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 33,100 | 359,000 | 0.10% | ||
| 49 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 26,826 | 291,000 | 0.08% | ||
| 50 | HAMILTON LANE ADVISORS LLC | 26,347 | 286,000 | 0.08% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
