| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 888,250 | 18,662,000 | 14.64% | ||
| 2 | DSC Advisors, L.P. | 907,358 | 17,157,000 | 13.46% | ||
| 3 | Sio Capital Management, LLC | 666,729 | 14,008,000 | 10.99% | ||
| 4 | Tourbillon Capital Partners, L.P. | 611,686 | 12,852,000 | 10.08% | ||
| 5 | DEERFIELD MANAGEMENT COMPANY, L.P. | 458,332 | 9,630,000 | 7.55% | ||
| 6 | PERCEPTIVE ADVISORS LLC | 371,066 | 7,796,000 | 6.11% | ||
| 7 | EMERALD MUTUAL FUND ADVISERS TRUST | 331,142 | 6,957,000 | 5.46% | ||
| 8 | EMERALD ADVISERS, LLC | 321,313 | 6,751,000 | 5.29% | ||
| 9 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 215,000 | 4,517,000 | 3.54% | ||
| 10 | PUTNAM INVESTMENTS LLC | 215,000 | 4,517,000 | 3.54% | ||
| 11 | WALL STREET ASSOCIATES | 199,343 | 4,188,000 | 3.28% | ||
| 12 | BlackRock Fund Advisors | 144,714 | 3,040,000 | 2.38% | ||
| 13 | CREDIT SUISSE AG/ | 123,305 | 2,591,000 | 2.03% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 104,390 | 2,193,000 | 1.72% | ||
| 15 | MARSHALL WACE, LLP | 86,233 | 1,812,000 | 1.42% | ||
| 16 | VANGUARD GROUP INC | 74,774 | 1,571,000 | 1.23% | ||
| 17 | DAFNA Capital Management LLC | 63,400 | 1,332,000 | 1.04% | ||
| 18 | Cormorant Asset Management, LP | 50,000 | 1,051,000 | 0.82% | ||
| 19 | BAMCO INC /NY/ | 41,600 | 874,000 | 0.69% | ||
| 20 | WADDELL & REED FINANCIAL INC | 40,000 | 840,000 | 0.66% | ||
| 21 | STATE STREET CORP | 36,604 | 770,000 | 0.60% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 36,611 | 769,000 | 0.60% | ||
| 23 | DSC Advisors, L.P. | 31,240 | 656,000 | 0.51% | Call | |
| 24 | BlackRock Investment Management, LLC | 19,328 | 406,000 | 0.32% | ||
| 25 | TIAA CREF INVESTMENT MANAGEMENT LLC | 16,023 | 337,000 | 0.26% | ||
| 26 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 15,800 | 332,000 | 0.26% | ||
| 27 | MILLENNIUM MANAGEMENT LLC | 13,628 | 286,000 | 0.22% | ||
| 28 | Bank of New York Mellon Corp | 11,713 | 246,000 | 0.19% | ||
| 29 | NORTHERN TRUST CORP | 11,462 | 241,000 | 0.19% | ||
| 30 | GOLDMAN SACHS GROUP INC | 10,820 | 227,000 | 0.18% | ||
| 31 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 10,100 | 212,000 | 0.17% | ||
| 32 | NORGES BANK | 9,700 | 204,000 | 0.16% | ||
| 33 | TEACHERS ADVISORS, LLC | 5,628 | 118,000 | 0.09% | ||
| 34 | UBS Group AG | 4,321 | 91,000 | 0.07% | ||
| 35 | MORGAN STANLEY | 3,403 | 71,000 | 0.06% | ||
| 36 | Tower Research Capital LLC (TRC) | 2,781 | 58,000 | 0.05% | ||
| 37 | BLACKROCK ADVISORS LLC | 2,175 | 46,000 | 0.04% | ||
| 38 | STRS OHIO | 1,800 | 37,000 | 0.03% | ||
| 39 | Nationwide Fund Advisors | 1,116 | 23,000 | 0.02% | ||
| 40 | BNP PARIBAS FINANCIAL MARKETS | 1,024 | 21,514 | 0.02% | ||
| 41 | ROYAL BANK OF CANADA | 200 | 4,000 | 0.00% | ||
| 42 | CITIGROUP INC | 151 | 3,000 | 0.00% | ||
| 43 | BANK OF MONTREAL /CAN/ | 28 | 1,000 | 0.00% | ||
| 44 | WELLS FARGO & COMPANY/MN | 23 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
