| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 17,549,733 | 681,456,000 | 16.05% | ||
| 2 | Clearbridge Investments, LLC | 8,988,756 | 349,033,000 | 8.22% | ||
| 3 | Artisan Partners Limited Partnership | 7,368,499 | 286,119,000 | 6.74% | ||
| 4 | VANGUARD GROUP INC | 7,257,516 | 281,809,000 | 6.64% | ||
| 5 | BB BIOTECH AG | 6,636,526 | 257,696,000 | 6.07% | ||
| 6 | WADDELL & REED FINANCIAL INC | 5,494,100 | 213,336,000 | 5.02% | ||
| 7 | BlackRock Fund Advisors | 4,120,458 | 159,997,000 | 3.77% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 3,088,420 | 119,923,000 | 2.82% | ||
| 9 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,754,750 | 106,967,000 | 2.52% | ||
| 10 | STATE STREET CORP | 2,676,552 | 103,933,000 | 2.45% | ||
| 11 | FRANKLIN RESOURCES INC | 2,083,967 | 80,921,000 | 1.91% | ||
| 12 | PINNACLE ASSOCIATES LTD | 1,845,727 | 71,670,000 | 1.69% | ||
| 13 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 1,832,109 | 71,141,000 | 1.68% | ||
| 14 | JENNISON ASSOCIATES LLC | 1,747,004 | 67,836,000 | 1.60% | ||
| 15 | NORTHERN TRUST CORP | 1,379,382 | 53,561,000 | 1.26% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,376,700 | 53,457,000 | 1.26% | Put | |
| 17 | EAGLE ASSET MANAGEMENT INC | 1,333,177 | 51,767,000 | 1.22% | ||
| 18 | ALTRINSIC GLOBAL ADVISORS LLC | 1,261,795 | 48,995,000 | 1.15% | ||
| 19 | STIFEL FINANCIAL CORP | 1,062,436 | 41,254,000 | 0.97% | ||
| 20 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,034,930 | 40,186,000 | 0.95% | ||
| 21 | ALLIANCEBERNSTEIN L.P. | 969,767 | 37,656,000 | 0.89% | ||
| 22 | Global Thematic Partners, LLC | 847,196 | 32,898,000 | 0.77% | ||
| 23 | Apex Capital Management | 843,791 | 32,764,000 | 0.77% | ||
| 24 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 791,697 | 30,742,000 | 0.72% | ||
| 25 | GOLDMAN SACHS GROUP INC | 776,305 | 30,144,000 | 0.71% | ||
| 26 | NORGES BANK | 752,077 | 29,203,000 | 0.69% | ||
| 27 | Bank of New York Mellon Corp | 726,675 | 28,217,000 | 0.66% | ||
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 719,313 | 27,931,000 | 0.66% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 702,311 | 27,270,000 | 0.64% | ||
| 30 | DOWLING & YAHNKE LLC | 676,298 | 26,261,000 | 0.62% | ||
| 31 | ROYAL BANK OF CANADA | 589,090 | 22,875,000 | 0.54% | ||
| 32 | VOYA INVESTMENT MANAGEMENT LLC | 576,237 | 22,375,000 | 0.53% | ||
| 33 | TIAA CREF INVESTMENT MANAGEMENT LLC | 574,732 | 22,317,000 | 0.53% | ||
| 34 | WELLS FARGO & COMPANY/MN | 553,537 | 21,494,000 | 0.51% | ||
| 35 | DEUTSCHE BANK AG\ | 546,232 | 21,207,000 | 0.50% | ||
| 36 | SCOUT INVESTMENTS, INC. | 524,247 | 20,357,000 | 0.48% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 502,800 | 19,524,000 | 0.46% | Call | |
| 38 | BLACKROCK ADVISORS LLC | 487,739 | 18,939,000 | 0.45% | ||
| 39 | MANAGED ACCOUNT ADVISORS LLC | 471,589 | 18,311,000 | 0.43% | ||
| 40 | TEACHERS ADVISORS, LLC | 467,296 | 18,145,000 | 0.43% | ||
| 41 | AMERICAN CENTURY COMPANIES INC | 463,837 | 18,011,000 | 0.42% | ||
| 42 | COLUMBUS CIRCLE INVESTORS | 461,519 | 17,921,000 | 0.42% | ||
| 43 | PANAGORA ASSET MANAGEMENT INC | 455,754 | 17,697,000 | 0.42% | ||
| 44 | Artal Group S.A. | 455,000 | 17,668,000 | 0.42% | ||
| 45 | GOLDMAN SACHS GROUP INC | 370,000 | 14,367,000 | 0.34% | Call | |
| 46 | GOLDMAN SACHS GROUP INC | 370,000 | 14,367,000 | 0.34% | Put | |
| 47 | RAINIER INVESTMENT MANAGEMENT LLC | 364,140 | 14,139,000 | 0.33% | ||
| 48 | JPMORGAN CHASE & CO | 357,575 | 13,885,000 | 0.33% | ||
| 49 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 350,159 | 13,597,000 | 0.32% | ||
| 50 | BlackRock Investment Management, LLC | 337,105 | 13,090,000 | 0.31% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
