| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 17,531,733 | 1,082,409,000 | 16.34% | ||
| 2 | Clearbridge Investments, LLC | 9,034,520 | 557,791,000 | 8.42% | ||
| 3 | VANGUARD GROUP INC | 7,271,871 | 448,965,000 | 6.78% | ||
| 4 | BB BIOTECH AG | 5,976,526 | 368,991,000 | 5.57% | ||
| 5 | WADDELL & REED FINANCIAL INC | 5,450,400 | 336,507,000 | 5.08% | ||
| 6 | BlackRock Fund Advisors | 4,471,458 | 276,068,000 | 4.17% | ||
| 7 | Artisan Partners Limited Partnership | 3,852,643 | 237,862,000 | 3.59% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 2,983,821 | 184,221,000 | 2.78% | ||
| 9 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,678,378 | 165,363,000 | 2.50% | ||
| 10 | STATE STREET CORP | 2,580,447 | 159,317,000 | 2.40% | ||
| 11 | FRANKLIN RESOURCES INC | 2,067,949 | 127,676,000 | 1.93% | ||
| 12 | PINNACLE ASSOCIATES LTD | 1,917,838 | 118,407,000 | 1.79% | ||
| 13 | JENNISON ASSOCIATES LLC | 1,725,800 | 106,551,000 | 1.61% | ||
| 14 | FIRST TRUST ADVISORS LP | 1,559,143 | 96,261,000 | 1.45% | ||
| 15 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 1,466,932 | 90,568,000 | 1.37% | ||
| 16 | NORTHERN TRUST CORP | 1,346,893 | 83,157,000 | 1.26% | ||
| 17 | EAGLE ASSET MANAGEMENT INC | 1,309,952 | 80,876,000 | 1.22% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,138,000 | 70,260,000 | 1.06% | Put | |
| 19 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,097,668 | 67,770,022 | 1.02% | ||
| 20 | BLACKROCK ADVISORS LLC | 1,080,905 | 66,735,000 | 1.01% | ||
| 21 | STIFEL FINANCIAL CORP | 864,888 | 60,477,000 | 0.91% | ||
| 22 | DEUTSCHE BANK AG\ | 928,678 | 57,334,000 | 0.87% | ||
| 23 | ALLIANCEBERNSTEIN L.P. | 914,542 | 56,464,000 | 0.85% | ||
| 24 | Apex Capital Management | 887,519 | 54,795,000 | 0.83% | ||
| 25 | NORGES BANK | 880,326 | 54,351,000 | 0.82% | ||
| 26 | Global Thematic Partners, LLC | 841,476 | 51,957,000 | 0.78% | ||
| 27 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 750,897 | 46,360,000 | 0.70% | ||
| 28 | Bank of New York Mellon Corp | 714,450 | 44,110,000 | 0.67% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 708,172 | 43,722,000 | 0.66% | ||
| 30 | DOWLING & YAHNKE LLC | 676,313 | 41,756,000 | 0.63% | ||
| 31 | WELLS FARGO & COMPANY/MN | 596,730 | 36,842,000 | 0.56% | ||
| 32 | VOYA INVESTMENT MANAGEMENT LLC | 583,258 | 36,011,000 | 0.54% | ||
| 33 | TIAA CREF INVESTMENT MANAGEMENT LLC | 551,374 | 34,042,000 | 0.51% | ||
| 34 | ALTRINSIC GLOBAL ADVISORS LLC | 544,583 | 33,622,000 | 0.51% | ||
| 35 | ROYAL BANK OF CANADA | 527,032 | 32,539,000 | 0.49% | ||
| 36 | AMERICAN CENTURY COMPANIES INC | 500,466 | 30,899,000 | 0.47% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 488,254 | 30,145,000 | 0.45% | ||
| 38 | MANAGED ACCOUNT ADVISORS LLC | 486,279 | 30,023,000 | 0.45% | ||
| 39 | PANAGORA ASSET MANAGEMENT INC | 479,135 | 29,582,000 | 0.45% | ||
| 40 | BlackRock Group LTD | 477,853 | 29,503,000 | 0.45% | ||
| 41 | TEACHERS ADVISORS, LLC | 467,568 | 28,868,000 | 0.44% | ||
| 42 | GOLDMAN SACHS GROUP INC | 449,399 | 27,746,000 | 0.42% | ||
| 43 | COLUMBUS CIRCLE INVESTORS | 415,447 | 25,650,000 | 0.39% | ||
| 44 | Artal Group S.A. | 405,000 | 25,005,000 | 0.38% | ||
| 45 | RAYMOND JAMES & ASSOCIATES | 386,782 | 23,880,000 | 0.36% | ||
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 381,600 | 23,560,000 | 0.36% | Call | |
| 47 | BlackRock Investment Management, LLC | 368,206 | 22,733,000 | 0.34% | ||
| 48 | JPMORGAN CHASE & CO | 366,306 | 22,616,000 | 0.34% | ||
| 49 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 359,236 | 22,180,000 | 0.33% | ||
| 50 | WELLINGTON MANAGEMENT GROUP LLP | 348,501 | 21,517,000 | 0.32% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
