| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 17,546,050 | 1,117,157,000 | 16.87% | ||
| 2 | Clearbridge Investments, LLC | 9,586,157 | 610,351,000 | 9.22% | ||
| 3 | VANGUARD GROUP INC | 8,013,026 | 510,189,000 | 7.71% | ||
| 4 | BB BIOTECH AG | 5,729,426 | 364,793,000 | 5.51% | ||
| 5 | WADDELL & REED FINANCIAL INC | 5,450,400 | 347,027,000 | 5.24% | ||
| 6 | BlackRock Fund Advisors | 4,594,099 | 292,506,000 | 4.42% | ||
| 7 | STATE STREET CORP | 3,170,831 | 201,885,000 | 3.05% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 3,160,897 | 201,254,000 | 3.04% | ||
| 9 | PINNACLE ASSOCIATES LTD | 1,889,017 | 120,274,000 | 1.82% | ||
| 10 | FRANKLIN RESOURCES INC | 1,729,658 | 110,128,000 | 1.66% | ||
| 11 | NORTHERN TRUST CORP | 1,571,219 | 100,039,000 | 1.51% | ||
| 12 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,489,258 | 94,821,000 | 1.43% | ||
| 13 | BLACKROCK ADVISORS LLC | 1,397,615 | 88,986,000 | 1.34% | ||
| 14 | FIRST TRUST ADVISORS LP | 1,385,594 | 88,221,000 | 1.33% | ||
| 15 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 1,248,614 | 79,499,000 | 1.20% | ||
| 16 | WELLINGTON MANAGEMENT GROUP LLP | 1,176,083 | 74,881,000 | 1.13% | ||
| 17 | GOLDMAN SACHS GROUP INC | 1,108,197 | 70,558,000 | 1.07% | ||
| 18 | EAGLE ASSET MANAGEMENT INC | 1,080,228 | 68,778,000 | 1.04% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,071,700 | 68,235,000 | 1.03% | Put | |
| 20 | ALLIANCEBERNSTEIN L.P. | 1,050,658 | 66,895,000 | 1.01% | ||
| 21 | DEUTSCHE BANK AG\ | 1,007,482 | 64,142,000 | 0.97% | ||
| 22 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 974,651 | 62,056,029 | 0.94% | ||
| 23 | BlackRock Group LTD | 969,301 | 61,716,000 | 0.93% | ||
| 24 | NORGES BANK | 955,196 | 60,818,000 | 0.92% | ||
| 25 | Apex Capital Management | 928,654 | 59,127,000 | 0.89% | ||
| 26 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 913,980 | 58,193,000 | 0.88% | ||
| 27 | Global Thematic Partners, LLC | 866,770 | 55,190,000 | 0.83% | ||
| 28 | Bank of New York Mellon Corp | 770,229 | 49,040,000 | 0.74% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 768,047 | 48,877,000 | 0.74% | ||
| 30 | DOWLING & YAHNKE LLC | 676,323 | 43,061,000 | 0.65% | ||
| 31 | STIFEL FINANCIAL CORP | 599,129 | 38,147,000 | 0.58% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 584,900 | 37,241,000 | 0.56% | Call | |
| 33 | WELLS FARGO & COMPANY/MN | 578,705 | 36,847,000 | 0.56% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 550,631 | 35,059,000 | 0.53% | ||
| 35 | Invesco Ltd. | 513,961 | 32,724,000 | 0.49% | ||
| 36 | PANAGORA ASSET MANAGEMENT INC | 498,653 | 31,749,000 | 0.48% | ||
| 37 | AMERICAN CENTURY COMPANIES INC | 494,383 | 31,477,000 | 0.48% | ||
| 38 | MANAGED ACCOUNT ADVISORS LLC | 494,122 | 31,460,000 | 0.48% | ||
| 39 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 453,993 | 28,906,000 | 0.44% | ||
| 40 | ROYAL BANK OF CANADA | 452,941 | 28,839,000 | 0.44% | ||
| 41 | RAYMOND JAMES & ASSOCIATES | 443,154 | 28,216,000 | 0.43% | ||
| 42 | VOYA INVESTMENT MANAGEMENT LLC | 423,053 | 26,936,000 | 0.41% | ||
| 43 | BlackRock Investment Management, LLC | 404,622 | 25,762,000 | 0.39% | ||
| 44 | Artal Group S.A. | 400,000 | 25,468,000 | 0.38% | ||
| 45 | TEACHERS ADVISORS, LLC | 397,864 | 25,332,000 | 0.38% | ||
| 46 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 379,530 | 24,165,000 | 0.36% | ||
| 47 | COLUMBUS CIRCLE INVESTORS | 362,032 | 23,051,000 | 0.35% | ||
| 48 | SCOUT INVESTMENTS, INC. | 348,598 | 22,195,000 | 0.34% | ||
| 49 | MORGAN STANLEY | 345,819 | 22,019,000 | 0.33% | ||
| 50 | JPMORGAN CHASE & CO | 344,906 | 21,960,000 | 0.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
