| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 17,687,647 | 714,935,000 | 16.36% | ||
| 2 | Clearbridge Investments, LLC | 9,385,080 | 379,345,000 | 8.68% | ||
| 3 | VANGUARD GROUP INC | 8,807,776 | 356,009,000 | 8.15% | ||
| 4 | BAILLIE GIFFORD & CO | 7,899,383 | 318,686,000 | 7.29% | ||
| 5 | BB BIOTECH AG | 6,634,838 | 268,180,000 | 6.14% | ||
| 6 | WADDELL & REED FINANCIAL INC | 5,770,300 | 233,236,000 | 5.34% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 3,047,646 | 123,186,000 | 2.82% | ||
| 8 | BlackRock Fund Advisors | 2,792,995 | 112,893,000 | 2.58% | ||
| 9 | STATE STREET CORP | 2,498,826 | 100,996,000 | 2.31% | ||
| 10 | FIRST TRUST ADVISORS LP | 2,252,501 | 91,046,000 | 2.08% | ||
| 11 | FRANKLIN RESOURCES INC | 1,972,454 | 79,726,000 | 1.82% | ||
| 12 | PINNACLE ASSOCIATES LTD | 1,778,325 | 71,880,000 | 1.65% | ||
| 13 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,677,543 | 67,806,000 | 1.55% | ||
| 14 | DEUTSCHE BANK AG\ | 1,323,445 | 53,491,000 | 1.22% | ||
| 15 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 1,178,628 | 47,640,000 | 1.09% | ||
| 16 | GOLDMAN SACHS GROUP INC | 1,134,957 | 45,875,000 | 1.05% | ||
| 17 | Apex Capital Management | 1,019,618 | 41,213,000 | 0.94% | ||
| 18 | NORGES BANK | 1,019,236 | 41,197,000 | 0.94% | ||
| 19 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 990,262 | 40,025,000 | 0.92% | ||
| 20 | ALLIANCEBERNSTEIN L.P. | 959,952 | 38,801,000 | 0.89% | ||
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 941,000 | 38,035,000 | 0.87% | Put | |
| 22 | BLACKROCK ADVISORS LLC | 869,398 | 35,141,000 | 0.80% | ||
| 23 | Global Thematic Partners, LLC | 782,452 | 31,624,000 | 0.72% | ||
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 725,380 | 29,301,000 | 0.67% | ||
| 25 | BANK OF AMERICA CORP /DE/ | 696,863 | 28,168,000 | 0.64% | ||
| 26 | DOWLING & YAHNKE LLC | 676,379 | 27,339,000 | 0.63% | ||
| 27 | BlackRock Group LTD | 658,990 | 26,635,000 | 0.61% | ||
| 28 | NORTHERN TRUST CORP | 627,075 | 25,346,000 | 0.58% | ||
| 29 | STIFEL FINANCIAL CORP | 598,474 | 24,190,000 | 0.55% | ||
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 584,669 | 23,632,000 | 0.54% | ||
| 31 | AQR CAPITAL MANAGEMENT LLC | 563,753 | 22,787,000 | 0.52% | ||
| 32 | CAPITAL FUND MANAGEMENT S.A. | 558,743 | 22,584,000 | 0.52% | ||
| 33 | Bank of New York Mellon Corp | 558,607 | 22,579,000 | 0.52% | ||
| 34 | Mitsubishi UFJ Trust & Banking Corp | 555,661 | 22,460,000 | 0.51% | ||
| 35 | WELLS FARGO & COMPANY/MN | 533,096 | 21,547,000 | 0.49% | ||
| 36 | AMERICAN CENTURY COMPANIES INC | 507,415 | 20,510,000 | 0.47% | ||
| 37 | RAYMOND JAMES & ASSOCIATES | 486,519 | 19,665,000 | 0.45% | ||
| 38 | RENAISSANCE TECHNOLOGIES LLC | 476,814 | 19,273,000 | 0.44% | ||
| 39 | NEW YORK STATE COMMON RETIREMENT FUND | 454,531 | 18,372,000 | 0.42% | ||
| 40 | WELLINGTON MANAGEMENT GROUP LLP | 424,018 | 17,139,000 | 0.39% | ||
| 41 | TWO SIGMA ADVISERS, LP | 395,505 | 16,467,000 | 0.38% | ||
| 42 | Artal Group S.A. | 400,000 | 16,168,000 | 0.37% | ||
| 43 | TIAA CREF INVESTMENT MANAGEMENT LLC | 381,877 | 15,435,000 | 0.35% | ||
| 44 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 374,503 | 15,138,000 | 0.35% | ||
| 45 | CREDIT SUISSE AG/ | 336,040 | 13,582,000 | 0.31% | ||
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 325,600 | 13,161,000 | 0.30% | Call | |
| 47 | AXA S.A. | 323,518 | 13,077,000 | 0.30% | ||
| 48 | TWO SIGMA INVESTMENTS, LP | 320,611 | 12,959,000 | 0.30% | ||
| 49 | WILLIAM HARRIS INVESTORS INC | 317,301 | 12,826,000 | 0.29% | ||
| 50 | Sumitomo Mitsui Trust Group, Inc. | 315,165 | 12,739,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
