| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,412,807 | 10,750,000 | 15.88% | ||
| 2 | FRANKLIN RESOURCES INC | 3,197,712 | 10,073,000 | 14.88% | ||
| 3 | ProQuest Associates IV LLC | 1,900,000 | 5,985,000 | 8.84% | ||
| 4 | BlackRock Fund Advisors | 1,659,876 | 5,229,000 | 7.72% | ||
| 5 | VANGUARD GROUP INC | 1,558,555 | 4,910,000 | 7.25% | ||
| 6 | PERCEPTIVE ADVISORS LLC | 1,459,627 | 4,598,000 | 6.79% | ||
| 7 | Broadfin Capital, LLC | 1,154,674 | 3,637,000 | 5.37% | ||
| 8 | Sio Capital Management, LLC | 901,115 | 2,839,000 | 4.19% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 866,924 | 2,731,000 | 4.03% | ||
| 10 | STATE STREET CORP | 704,814 | 2,222,000 | 3.28% | ||
| 11 | Abingworth LLP | 512,036 | 1,531,000 | 2.26% | ||
| 12 | Rock Springs Capital Management LP | 450,000 | 1,418,000 | 2.09% | ||
| 13 | NORTHERN TRUST CORP | 417,262 | 1,314,000 | 1.94% | ||
| 14 | D.A. DAVIDSON & CO. | 317,700 | 1,000,000 | 1.48% | ||
| 15 | Rhenman & Partners Asset Management AB | 300,000 | 945,000 | 1.40% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 279,265 | 879,000 | 1.30% | ||
| 17 | Bank of New York Mellon Corp | 222,807 | 702,000 | 1.04% | ||
| 18 | UBS Group AG | 209,840 | 661,000 | 0.98% | ||
| 19 | Allianz Asset Management GmbH | 155,403 | 490,000 | 0.72% | ||
| 20 | BlackRock Investment Management, LLC | 152,347 | 480,000 | 0.71% | ||
| 21 | WEXFORD CAPITAL LP | 145,622 | 459,000 | 0.68% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 131,730 | 415,000 | 0.61% | ||
| 23 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 102,125 | 322,000 | 0.48% | ||
| 24 | Hilltop Park Associates LLC | 100,000 | 315,000 | 0.47% | ||
| 25 | SABBY MANAGEMENT, LLC | 94,201 | 297,000 | 0.44% | ||
| 26 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 83,243 | 262,000 | 0.39% | ||
| 27 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 73,929 | 233,000 | 0.34% | ||
| 28 | TEACHERS ADVISORS, LLC | 63,458 | 200,000 | 0.30% | ||
| 29 | HighTower Advisors, LLC | 61,900 | 195,000 | 0.29% | ||
| 30 | Weiss Multi-Strategy Advisers LLC | 58,500 | 184,000 | 0.27% | ||
| 31 | RHUMBLINE ADVISERS | 56,699 | 179,000 | 0.26% | ||
| 32 | TFS CAPITAL LLC | 55,622 | 175,000 | 0.26% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 53,200 | 168,000 | 0.25% | Put | |
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 51,939 | 164,000 | 0.24% | ||
| 35 | NEW YORK STATE COMMON RETIREMENT FUND | 38,000 | 120,000 | 0.18% | ||
| 36 | GROUP ONE TRADING LLC | 31,142 | 98,000 | 0.14% | ||
| 37 | ProShare Advisors LLC | 29,990 | 94,000 | 0.14% | ||
| 38 | GOLDMAN SACHS GROUP INC | 27,139 | 85,000 | 0.13% | ||
| 39 | PANAGORA ASSET MANAGEMENT INC | 26,468 | 83,000 | 0.12% | ||
| 40 | Nationwide Fund Advisors | 25,816 | 81,000 | 0.12% | ||
| 41 | WHITE PINE CAPITAL LLC | 25,000 | 79,000 | 0.12% | ||
| 42 | BANK OF AMERICA CORP /DE/ | 24,255 | 76,000 | 0.11% | ||
| 43 | AMERICAN INTERNATIONAL GROUP, INC. | 22,675 | 71,426 | 0.11% | ||
| 44 | Virtu KCG Holdings LLC | 22,173 | 70,000 | 0.10% | ||
| 45 | ALLIANCEBERNSTEIN L.P. | 21,600 | 68,000 | 0.10% | ||
| 46 | VOYA INVESTMENT MANAGEMENT LLC | 19,647 | 62,000 | 0.09% | ||
| 47 | Jefferies Group LLC | 19,683 | 62,000 | 0.09% | ||
| 48 | CREDIT SUISSE AG/ | 19,422 | 61,000 | 0.09% | ||
| 49 | MILLENNIUM MANAGEMENT LLC | 18,906 | 60,000 | 0.09% | ||
| 50 | BLACKROCK ADVISORS LLC | 17,813 | 56,000 | 0.08% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
