| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 11,946,100 | 5,854,000 | 30.89% | ||
| 2 | BVF INC/IL | 5,111,293 | 2,505,000 | 13.22% | ||
| 3 | BAKER BROS. ADVISORS LP | 4,707,464 | 2,307,000 | 12.17% | ||
| 4 | VANGUARD GROUP INC | 4,062,609 | 1,991,000 | 10.51% | ||
| 5 | Alyeska Investment Group, L.P. | 2,969,381 | 1,455,000 | 7.68% | Call | |
| 6 | MPM ASSET MANAGEMENT LLC | 2,551,851 | 1,250,000 | 6.60% | ||
| 7 | ProQuest Associates IV LLC | 2,551,851 | 1,250,000 | 6.60% | ||
| 8 | DEUTSCHE BANK AG\ | 954,048 | 467,000 | 2.46% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 678,116 | 332,000 | 1.75% | ||
| 10 | PERKINS CAPITAL MANAGEMENT INC | 623,250 | 305,000 | 1.61% | ||
| 11 | SHEPHERD KAPLAN KROCHUK, LLC | 581,886 | 285,000 | 1.50% | ||
| 12 | Creative Planning | 443,700 | 217,000 | 1.15% | ||
| 13 | RENAISSANCE TECHNOLOGIES LLC | 393,055 | 193,000 | 1.02% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 262,264 | 129,000 | 0.68% | ||
| 15 | DIMENSIONAL FUND ADVISORS LP | 218,303 | 107,000 | 0.56% | ||
| 16 | Bank of New York Mellon Corp | 161,785 | 79,000 | 0.42% | ||
| 17 | Ancora Advisors LLC | 113,711 | 56,000 | 0.30% | ||
| 18 | NORTHERN TRUST CORP | 102,959 | 50,000 | 0.26% | ||
| 19 | HighTower Advisors, LLC | 53,500 | 26,000 | 0.14% | ||
| 20 | UBS Group AG | 31,625 | 16,000 | 0.08% | ||
| 21 | GUGGENHEIM CAPITAL LLC | 27,835 | 14,000 | 0.07% | ||
| 22 | LAU ASSOCIATES LLC | 20,000 | 10,000 | 0.05% | ||
| 23 | Virtu KCG Holdings LLC | 18,714 | 9,000 | 0.05% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 15,800 | 8,000 | 0.04% | ||
| 25 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 14,226 | 7,000 | 0.04% | ||
| 26 | STATE STREET CORP | 13,124 | 6,000 | 0.03% | ||
| 27 | Cetera Advisor Networks LLC | 10,000 | 5,000 | 0.03% | ||
| 28 | Genesis Wealth Advisors, LLC | 10,000 | 4,900 | 0.03% | ||
| 29 | GROUP ONE TRADING LLC | 6,655 | 3,000 | 0.02% | ||
| 30 | EARNEST PARTNERS LLC | 5,400 | 3,000 | 0.02% | ||
| 31 | Pine River Capital Management L.P. | 1,250,000 | 2,000 | 0.01% | ||
| 32 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 2,139 | 1,000 | 0.01% | ||
| 33 | Corbenic Partners LLC | 1,500 | 1,000 | 0.01% | ||
| 34 | Hoxton Financial, Inc. | 1,091 | 1,000 | 0.01% | ||
| 35 | B. Riley Wealth Management, Inc. | 597 | 0 | 0.00% | ||
| 36 | MORGAN STANLEY | 700 | 0 | 0.00% | ||
| 37 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 4 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
