| 1 |
BAKER BROS. ADVISORS LP |
4,797,442 |
2,016,000 |
17.72% |
|
|
| 2 |
VANGUARD GROUP INC |
4,353,424 |
1,830,000 |
16.09% |
|
|
| 3 |
FRANKLIN RESOURCES INC |
3,870,877 |
1,627,000 |
14.30% |
|
|
| 4 |
BVF INC/IL |
3,696,961 |
1,554,000 |
13.66% |
|
|
| 5 |
Alyeska Investment Group, L.P. |
2,969,381 |
1,248,000 |
10.97% |
Call |
|
| 6 |
MPM ASSET MANAGEMENT LLC |
2,551,851 |
1,072,000 |
9.42% |
|
|
| 7 |
ProQuest Associates IV LLC |
1,275,925 |
536,000 |
4.71% |
|
|
| 8 |
GEODE CAPITAL MANAGEMENT, LLC |
678,116 |
285,000 |
2.51% |
|
|
| 9 |
SHEPHERD KAPLAN KROCHUK, LLC |
581,886 |
245,000 |
2.15% |
|
|
| 10 |
PERKINS CAPITAL MANAGEMENT INC |
567,250 |
238,000 |
2.09% |
|
|
| 11 |
Ancora Advisors LLC |
400,000 |
168,000 |
1.48% |
|
|
| 12 |
HighTower Advisors, LLC |
343,098 |
145,000 |
1.27% |
|
|
| 13 |
BlackRock Institutional Trust Company, N.A. |
239,234 |
101,000 |
0.89% |
|
|
| 14 |
Creative Planning |
190,306 |
80,000 |
0.70% |
|
|
| 15 |
Bank of New York Mellon Corp |
136,177 |
57,000 |
0.50% |
|
|
| 16 |
DIMENSIONAL FUND ADVISORS LP |
116,224 |
49,000 |
0.43% |
|
|
| 17 |
NORTHERN TRUST CORP |
102,959 |
43,000 |
0.38% |
|
|
| 18 |
MORGAN STANLEY |
39,266 |
17,000 |
0.15% |
|
|
| 19 |
BlackRock Fund Advisors |
25,136 |
11,000 |
0.10% |
|
|
| 20 |
TWO SIGMA SECURITIES, LLC |
23,411 |
10,000 |
0.09% |
|
|
| 21 |
LAU ASSOCIATES LLC |
20,000 |
8,000 |
0.07% |
|
|
| 22 |
BLACKROCK ADVISORS LLC |
15,428 |
6,000 |
0.05% |
|
|
| 23 |
STATE STREET CORP |
13,124 |
6,000 |
0.05% |
|
|
| 24 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
12,037 |
5,000 |
0.04% |
|
|
| 25 |
Cetera Advisor Networks LLC |
10,000 |
4,000 |
0.04% |
|
|
| 26 |
GROUP ONE TRADING LLC |
6,755 |
3,000 |
0.03% |
|
|
| 27 |
Tower Research Capital LLC (TRC) |
7,873 |
3,000 |
0.03% |
|
|
| 28 |
EARNEST PARTNERS LLC |
5,400 |
2,000 |
0.02% |
|
|
| 29 |
BANK OF AMERICA CORP /DE/ |
5,800 |
2,000 |
0.02% |
|
|
| 30 |
DEUTSCHE BANK AG\ |
3,001 |
1,000 |
0.01% |
|
|
| 31 |
BlackRock Finance, Inc. |
1,505 |
1,000 |
0.01% |
|
|
| 32 |
Corbenic Partners LLC |
1,500 |
1,000 |
0.01% |
|
|
| 33 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
2,139 |
1,000 |
0.01% |
|
|
| 34 |
Hoxton Financial, Inc. |
1,091 |
0 |
0.00% |
|
|
| 35 |
BARCLAYS PLC |
400 |
0 |
0.00% |
|
|
| 36 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
4 |
0 |
0.00% |
|
|
| 37 |
Pine River Capital Management L.P. |
1,250,000 |
0 |
0.00% |
|
|
