| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 10,153,000 | 5,889,000 | 28.27% | ||
| 2 | BVF INC/IL | 5,104,068 | 2,960,000 | 14.21% | ||
| 3 | BAKER BROS. ADVISORS LP | 4,707,464 | 2,730,000 | 13.11% | ||
| 4 | VANGUARD GROUP INC | 4,106,264 | 2,382,000 | 11.44% | ||
| 5 | Alyeska Investment Group, L.P. | 2,969,381 | 1,723,000 | 8.27% | Call | |
| 6 | MPM ASSET MANAGEMENT LLC | 2,551,851 | 1,480,000 | 7.11% | ||
| 7 | ProQuest Associates IV LLC | 1,275,925 | 740,000 | 3.55% | ||
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 678,116 | 393,000 | 1.89% | ||
| 9 | DEUTSCHE BANK AG\ | 628,600 | 364,000 | 1.75% | ||
| 10 | PERKINS CAPITAL MANAGEMENT INC | 615,750 | 357,000 | 1.71% | ||
| 11 | ASCEND CAPITAL, LLC | 599,200 | 347,000 | 1.67% | ||
| 12 | SHEPHERD KAPLAN KROCHUK, LLC | 581,886 | 337,000 | 1.62% | ||
| 13 | Creative Planning | 497,600 | 289,000 | 1.39% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 239,234 | 139,000 | 0.67% | ||
| 15 | Virtu KCG Holdings LLC | 224,626 | 130,000 | 0.62% | ||
| 16 | DIMENSIONAL FUND ADVISORS LP | 218,303 | 127,000 | 0.61% | ||
| 17 | MORGAN STANLEY | 207,085 | 120,000 | 0.58% | ||
| 18 | Ancora Advisors LLC | 136,711 | 79,000 | 0.38% | ||
| 19 | Bank of New York Mellon Corp | 135,570 | 79,000 | 0.38% | ||
| 20 | NORTHERN TRUST CORP | 102,959 | 60,000 | 0.29% | ||
| 21 | HighTower Advisors, LLC | 48,500 | 28,000 | 0.13% | ||
| 22 | GUGGENHEIM CAPITAL LLC | 31,807 | 18,000 | 0.09% | ||
| 23 | LAU ASSOCIATES LLC | 20,000 | 12,000 | 0.06% | ||
| 24 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 14,226 | 8,000 | 0.04% | ||
| 25 | STATE STREET CORP | 13,124 | 7,000 | 0.03% | ||
| 26 | Cetera Advisor Networks LLC | 10,000 | 6,000 | 0.03% | ||
| 27 | NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 10,100 | 6,000 | 0.03% | ||
| 28 | GROUP ONE TRADING LLC | 6,755 | 4,000 | 0.02% | ||
| 29 | EARNEST PARTNERS LLC | 5,400 | 3,000 | 0.01% | ||
| 30 | BANK OF AMERICA CORP /DE/ | 5,800 | 3,000 | 0.01% | ||
| 31 | Pine River Capital Management L.P. | 1,250,000 | 3,000 | 0.01% | ||
| 32 | UBS Group AG | 4,094 | 2,000 | 0.01% | ||
| 33 | Hoxton Financial, Inc. | 1,091 | 1,000 | 0.00% | ||
| 34 | Corbenic Partners LLC | 1,500 | 1,000 | 0.00% | ||
| 35 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 2,139 | 1,000 | 0.00% | ||
| 36 | WEALTHFRONT CORP | 3 | 0 | 0.00% | ||
| 37 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 4 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
