| 1 |
Novo Holdings A/S |
4,720,065 |
3,918,000 |
33.11% |
|
PRN |
| 2 |
Newtyn Management, LLC |
2,600,000 |
2,132,000 |
18.02% |
|
|
| 3 |
Clearbridge Investments, LLC |
1,970,117 |
1,635,000 |
13.82% |
|
|
| 4 |
Arbiter Partners Capital Management LLC |
1,834,806 |
1,523,000 |
12.87% |
|
|
| 5 |
VANGUARD GROUP INC |
662,572 |
543,000 |
4.59% |
|
|
| 6 |
683 Capital Management, LLC |
600,000 |
498,000 |
4.21% |
|
|
| 7 |
DELTEC ASSET MANAGEMENT LLC |
335,850 |
279,000 |
2.36% |
|
|
| 8 |
PRICE T ROWE ASSOCIATES INC /MD/ |
261,400 |
214,000 |
1.81% |
|
|
| 9 |
WHITEBOX ADVISORS LLC |
255,650 |
212,000 |
1.79% |
|
|
| 10 |
MILLENNIUM MANAGEMENT LLC |
216,083 |
179,000 |
1.51% |
Call |
|
| 11 |
DEUTSCHE BANK AG\ |
190,970 |
158,000 |
1.34% |
|
|
| 12 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
166,500 |
149,000 |
1.26% |
|
|
| 13 |
HIGHLAND CAPITAL MANAGEMENT LP |
69,326 |
58,000 |
0.49% |
|
|
| 14 |
CSS LLC/IL |
59,980 |
50,000 |
0.42% |
|
|
| 15 |
Verition Fund Management LLC |
59,890 |
49,000 |
0.41% |
|
|
| 16 |
Ghost Tree Capital, LLC |
55,150 |
46,000 |
0.39% |
|
|
| 17 |
Yakira Capital Management, Inc. |
45,300 |
38,000 |
0.32% |
|
|
| 18 |
LPL Financial LLC |
37,769 |
31,000 |
0.26% |
|
|
| 19 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
29,992 |
25,000 |
0.21% |
|
|
| 20 |
GABELLI & Co INVESTMENT ADVISERS, INC. |
25,569 |
21,000 |
0.18% |
|
|
| 21 |
NORTHERN TRUST CORP |
19,125 |
16,000 |
0.14% |
|
|
| 22 |
NatWest Group plc |
13,941 |
12,000 |
0.10% |
|
|
| 23 |
MORGAN STANLEY |
12,900 |
11,000 |
0.09% |
|
|
| 24 |
GABELLI FUNDS LLC |
11,500 |
10,000 |
0.08% |
|
|
| 25 |
TD ASSET MANAGEMENT INC |
10,300 |
8,000 |
0.07% |
|
|
| 26 |
Tower Research Capital LLC (TRC) |
5,701 |
5,000 |
0.04% |
|
|
| 27 |
UBS AG |
6,485 |
5,000 |
0.04% |
|
|
| 28 |
CITIGROUP INC |
3,001 |
2,000 |
0.02% |
|
|
| 29 |
DIMENSIONAL FUND ADVISORS LP |
2,878 |
2,000 |
0.02% |
|
|
| 30 |
BANK OF MONTREAL /CAN/ |
1,000 |
1,000 |
0.01% |
|
|
| 31 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
637 |
1,000 |
0.01% |
|
|
| 32 |
BANK OF AMERICA CORP /DE/ |
1,000 |
1,000 |
0.01% |
|
|
| 33 |
BNP PARIBAS FINANCIAL MARKETS |
421 |
345 |
0.00% |
|
|
| 34 |
AMERIPRISE FINANCIAL INC |
240 |
0 |
0.00% |
|
|
| 35 |
CapWealth Advisors, LLC |
500 |
0 |
0.00% |
|
|
| 36 |
Creative Planning |
500 |
0 |
0.00% |
|
|
| 37 |
WELLS FARGO & COMPANY/MN |
1 |
0 |
0.00% |
|
|
