| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Newtyn Management, LLC | 4,950,393 | 23,663,000 | 29.05% | ||
| 2 | Novo Holdings A/S | 4,720,065 | 22,562,000 | 27.70% | PRN | |
| 3 | Clearbridge Investments, LLC | 1,970,117 | 9,417,000 | 11.56% | ||
| 4 | Arbiter Partners Capital Management LLC | 1,925,027 | 9,202,000 | 11.30% | ||
| 5 | 683 Capital Management, LLC | 701,988 | 3,356,000 | 4.12% | ||
| 6 | VANGUARD GROUP INC | 662,572 | 3,167,000 | 3.89% | ||
| 7 | PURA VIDA INVESTMENTS, LLC | 545,136 | 2,606,000 | 3.20% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 217,983 | 1,042,000 | 1.28% | Call | |
| 9 | Tetragon Partners GP Ltd | 195,000 | 932,000 | 1.14% | ||
| 10 | Ghost Tree Capital, LLC | 185,000 | 884,000 | 1.09% | ||
| 11 | DEUTSCHE BANK AG\ | 175,000 | 836,000 | 1.03% | ||
| 12 | DELTEC ASSET MANAGEMENT LLC | 150,000 | 717,000 | 0.88% | ||
| 13 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 166,500 | 709,000 | 0.87% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 132,507 | 633,000 | 0.78% | ||
| 15 | HIGHLAND CAPITAL MANAGEMENT LP | 69,326 | 331,000 | 0.41% | ||
| 16 | CSS LLC/IL | 54,980 | 263,000 | 0.32% | ||
| 17 | Yakira Capital Management, Inc. | 38,308 | 183,000 | 0.22% | SH | |
| 18 | LPL Financial LLC | 37,769 | 181,000 | 0.22% | ||
| 19 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 29,992 | 143,000 | 0.18% | ||
| 20 | MORGAN STANLEY | 29,700 | 142,000 | 0.17% | ||
| 21 | AQR CAPITAL MANAGEMENT LLC | 23,600 | 113,000 | 0.14% | ||
| 22 | GABELLI & Co INVESTMENT ADVISERS, INC. | 23,569 | 113,000 | 0.14% | ||
| 23 | NORTHERN TRUST CORP | 19,125 | 92,000 | 0.11% | ||
| 24 | NatWest Group plc | 13,941 | 67,000 | 0.08% | ||
| 25 | Tower Research Capital LLC (TRC) | 5,992 | 29,000 | 0.04% | ||
| 26 | UBS Group AG | 3,152 | 15,000 | 0.02% | ||
| 27 | DIMENSIONAL FUND ADVISORS LP | 2,878 | 14,000 | 0.02% | ||
| 28 | CITIGROUP INC | 2,547 | 12,000 | 0.01% | ||
| 29 | Creative Planning | 2,000 | 10,000 | 0.01% | ||
| 30 | BANK OF AMERICA CORP /DE/ | 2,000 | 10,000 | 0.01% | ||
| 31 | CREDIT SUISSE AG/ | 1 | 0 | 0.00% | ||
| 32 | WELLS FARGO & COMPANY/MN | 1 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
