| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BIOGEN INC | 498,212 | 210,365,000 | 7.99% | ||
| 2 | BIOMARIN | 1,409,031 | 175,593,000 | 6.67% | ||
| 3 | CELGENE CORP | 1,208,858 | 139,357,000 | 5.29% | ||
| 4 | GILEAD SCIENCES INC | 1,320,507 | 129,581,000 | 4.92% | ||
| 5 | INCYTE | 1,336,144 | 122,471,000 | 4.65% | ||
| 6 | ALLERGAN PLC | 374,407 | 111,431,000 | 4.23% | ||
| 7 | AMGEN INC | 663,575 | 106,072,000 | 4.03% | ||
| 8 | TEVA PHARMACEUTICAL INDS LTD | 1,660,583 | 103,454,000 | 3.93% | ||
| 9 | THERMO FISHER SCIENTIFIC INC | 587,136 | 78,876,000 | 3.00% | ||
| 10 | MYLAN N V | 1,206,838 | 71,626,000 | 2.72% | ||
| 11 | ALEXION PHARMACEUTIC | 396,324 | 68,683,000 | 2.61% | ||
| 12 | VERTEX PHARMACEUT | 509,600 | 60,118,000 | 2.28% | ||
| 13 | SHIRE PLC | 248,859 | 59,549,000 | 2.26% | ||
| 14 | AMICUS THERAPEUTICS INC | 4,986,138 | 54,249,000 | 2.06% | ||
| 15 | HALOZYME THERAPEUTICS INC | 3,727,551 | 53,229,000 | 2.02% | ||
| 16 | DR REDDYS LABS LTD | 928,962 | 53,044,000 | 2.01% | ||
| 17 | PFIZER INC | 1,492,057 | 51,909,000 | 1.97% | ||
| 18 | KERYX BIOPHARMACEUTICALS INCORPORATED | 3,825,256 | 48,696,000 | 1.85% | ||
| 19 | INTERCEPT PHARMACEUTICAL | 164,947 | 46,518,000 | 1.77% | ||
| 20 | PTC THERAPEUTICS INC | 753,141 | 45,829,000 | 1.74% | ||
| 21 | SEATTLE GENETICS INC | 1,260,275 | 44,551,000 | 1.69% | ||
| 22 | PERRIGO CO PLC | 268,624 | 44,471,000 | 1.69% | ||
| 23 | PORTOLA PHARMACEUTICALS INC | 1,162,730 | 44,137,000 | 1.68% | ||
| 24 | MALLINCKRODT PUB LTD CO SHS | 343,370 | 43,488,000 | 1.65% | ||
| 25 | ONCOMED PHARMACEUTICALS INC | 1,533,578 | 39,536,000 | 1.50% | ||
| 26 | SYNAGEVA BIOPHARMA CORP | 365,684 | 35,665,000 | 1.35% | ||
| 27 | MEDTRONIC PLC | 408,126 | 31,830,000 | 1.21% | ||
| 28 | ACHILLION PHARMACEUTICALS INC COM | 3,190,572 | 31,459,000 | 1.19% | ||
| 29 | ALDER BIOPHARMACEUTICALS INC | 1,072,437 | 30,951,000 | 1.18% | ||
| 30 | RELYPSA INC | 837,830 | 30,221,000 | 1.15% | ||
| 31 | UNITED THERAPEUTICS | 175,080 | 30,190,000 | 1.15% | ||
| 32 | SAGENT PHARMACEUTICALS INC | 1,170,083 | 27,204,000 | 1.03% | ||
| 33 | MEDIVATION INC | 208,889 | 26,961,000 | 1.02% | ||
| 34 | DEXCOM | 399,558 | 24,908,000 | 0.95% | ||
| 35 | Momenta Pharmaceuticals Inc | 1,584,010 | 24,077,000 | 0.91% | ||
| 36 | ALIGN TECHNOLOGY INC | 433,140 | 23,296,000 | 0.88% | ||
| 37 | ACCELERON PHARMA | 599,184 | 22,805,000 | 0.87% | ||
| 38 | ABBOTT LABS | 484,376 | 22,441,000 | 0.85% | ||
| 39 | TETRAPHASE PHARMACEUTICALS I COM | 605,393 | 22,182,000 | 0.84% | ||
| 40 | AKORN INC | 466,668 | 22,171,000 | 0.84% | ||
| 41 | KARYOPHARM THERAPEUTICS INC COM | 707,268 | 21,649,000 | 0.82% | ||
| 42 | CLOVIS ONCOLOGY INC | 249,152 | 18,495,000 | 0.70% | ||
| 43 | INTUITIVE SURGICAL INC | 30,191 | 15,247,000 | 0.58% | ||
| 44 | NXSTAGE MED INC COM | 876,042 | 15,156,000 | 0.58% | ||
| 45 | INVITAE CORP | 874,391 | 14,655,000 | 0.56% | ||
| 46 | Heartware International, Inc. | 153,815 | 13,500,000 | 0.51% | ||
| 47 | Ascendis Pharma | 731,660 | 12,694,000 | 0.48% | ||
| 48 | HCA HOLDINGS INC | 167,176 | 12,577,000 | 0.48% | ||
| 49 | NOVARTIS A G | 119,405 | 11,775,000 | 0.45% | ||
| 50 | AMPHASTAR PHARMACEUTICALS IN COM | 733,932 | 10,980,000 | 0.42% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001104659-15-038098, filed 2015.05.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
