| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | BlackRock Investment Management, LLC | 72,861 | 490,000 | 0.34% | ||
| 52 | MYCIO WEALTH PARTNERS, LLC | 75,000 | 505,000 | 0.35% | ||
| 53 | TIAA CREF INVESTMENT MANAGEMENT LLC | 86,154 | 580,000 | 0.40% | ||
| 54 | CREDIT SUISSE AG/ | 94,091 | 633,000 | 0.44% | ||
| 55 | Opus Point Partners Management, LLC | 99,959 | 673,000 | 0.47% | ||
| 56 | SPHERA FUNDS MANAGEMENT LTD. | 100,000 | 673,000 | 0.47% | ||
| 57 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 101,300 | 682,000 | 0.48% | ||
| 58 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 127,804 | 860,000 | 0.60% | ||
| 59 | Joel Isaacson & Co., LLC | 135,660 | 913,000 | 0.64% | ||
| 60 | EVENTIDE ASSET MANAGEMENT, LLC | 139,400 | 938,000 | 0.65% | ||
| 61 | GEODE CAPITAL MANAGEMENT, LLC | 146,902 | 988,000 | 0.69% | ||
| 62 | Bank of New York Mellon Corp | 164,892 | 1,110,000 | 0.77% | ||
| 63 | SHEPHERD KAPLAN KROCHUK, LLC | 214,784 | 1,445,000 | 1.01% | ||
| 64 | D. E. Shaw & Co., Inc. | 238,312 | 1,604,000 | 1.12% | ||
| 65 | BlackRock Institutional Trust Company, N.A. | 258,792 | 1,742,000 | 1.21% | ||
| 66 | NORTHERN TRUST CORP | 272,017 | 1,831,000 | 1.28% | ||
| 67 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 306,070 | 2,060,000 | 1.44% | ||
| 68 | STATE STREET CORP | 361,872 | 2,430,000 | 1.69% | ||
| 69 | WALL STREET ASSOCIATES | 367,200 | 2,471,000 | 1.72% | ||
| 70 | OppenheimerFunds, Inc. | 602,713 | 4,056,000 | 2.83% | ||
| 71 | SENZAR ASSET MANAGEMENT, LLC | 906,781 | 6,103,000 | 4.25% | ||
| 72 | FMR LLC | 971,601 | 6,539,000 | 4.56% | ||
| 73 | VANGUARD GROUP INC | 973,367 | 6,550,000 | 4.56% | ||
| 74 | MORGAN STANLEY | 973,857 | 6,554,000 | 4.57% | ||
| 75 | Cormorant Asset Management, LP | 1,000,000 | 6,730,000 | 4.69% | ||
| 76 | BlackRock Fund Advisors | 1,218,745 | 8,202,000 | 5.72% | ||
| 77 | Granahan Investment Management, LLC | 1,541,984 | 10,378,000 | 7.23% | ||
| 78 | Palo Alto Investors LP | 2,128,539 | 14,325,000 | 9.98% | ||
| 79 | PERCEPTIVE ADVISORS LLC | 6,574,060 | 44,243,000 | 30.83% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
