| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 6,574,060 | 27,874,000 | 35.34% | ||
| 2 | Palo Alto Investors LP | 2,135,739 | 9,056,000 | 11.48% | ||
| 3 | Granahan Investment Management, LLC | 1,582,237 | 6,709,000 | 8.51% | ||
| 4 | VANGUARD GROUP INC | 1,076,226 | 4,563,000 | 5.78% | ||
| 5 | FMR LLC | 1,040,114 | 4,410,000 | 5.59% | ||
| 6 | Cormorant Asset Management, LP | 850,000 | 3,604,000 | 4.57% | ||
| 7 | SENZAR ASSET MANAGEMENT, LLC | 798,381 | 3,385,000 | 4.29% | ||
| 8 | BlackRock Fund Advisors | 658,620 | 2,793,000 | 3.54% | ||
| 9 | MORGAN STANLEY | 342,436 | 1,452,000 | 1.84% | ||
| 10 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 320,170 | 1,358,000 | 1.72% | ||
| 11 | NORTHERN TRUST CORP | 228,502 | 969,000 | 1.23% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 211,969 | 899,000 | 1.14% | ||
| 13 | DEUTSCHE BANK AG\ | 197,766 | 838,000 | 1.06% | ||
| 14 | CREDIT SUISSE AG/ | 195,053 | 827,000 | 1.05% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 181,102 | 768,000 | 0.97% | ||
| 16 | MILLENNIUM MANAGEMENT LLC | 169,828 | 720,000 | 0.91% | ||
| 17 | SABBY MANAGEMENT, LLC | 142,700 | 605,000 | 0.77% | ||
| 18 | D. E. Shaw & Co., Inc. | 131,391 | 557,000 | 0.71% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 128,938 | 546,000 | 0.69% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 118,800 | 504,000 | 0.64% | Put | |
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 112,700 | 478,000 | 0.61% | Call | |
| 22 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 101,300 | 430,000 | 0.55% | ||
| 23 | Opus Point Partners Management, LLC | 99,959 | 424,000 | 0.54% | ||
| 24 | GOLDMAN SACHS GROUP INC | 99,866 | 423,000 | 0.54% | ||
| 25 | AMERICAN INTERNATIONAL GROUP, INC. | 81,349 | 344,920 | 0.44% | ||
| 26 | MYCIO WEALTH PARTNERS, LLC | 75,000 | 318,000 | 0.40% | ||
| 27 | JANE STREET GROUP, LLC | 71,556 | 303,000 | 0.38% | ||
| 28 | Joel Isaacson & Co., LLC | 70,660 | 300,000 | 0.38% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 64,632 | 274,000 | 0.35% | ||
| 30 | MARINER INVESTMENT GROUP LLC | 59,700 | 253,000 | 0.32% | ||
| 31 | Cornerstone Capital, Inc. | 59,200 | 251,000 | 0.32% | ||
| 32 | Creative Planning | 45,200 | 192,000 | 0.24% | ||
| 33 | COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 44,194 | 187,000 | 0.24% | ||
| 34 | GROUP ONE TRADING LLC | 42,575 | 181,000 | 0.23% | ||
| 35 | Bank of New York Mellon Corp | 38,402 | 163,000 | 0.21% | ||
| 36 | Paloma Partners Management Co | 38,200 | 162,000 | 0.21% | ||
| 37 | ProShare Advisors LLC | 35,425 | 150,000 | 0.19% | ||
| 38 | MARSHALL WACE, LLP | 29,009 | 123,000 | 0.16% | ||
| 39 | WELLS FARGO & COMPANY/MN | 28,694 | 121,000 | 0.15% | ||
| 40 | LMR Partners LLP | 28,239 | 120,000 | 0.15% | ||
| 41 | STATE STREET CORP | 26,500 | 112,000 | 0.14% | ||
| 42 | OSTERWEIS CAPITAL MANAGEMENT INC | 25,709 | 109,000 | 0.14% | ||
| 43 | TUDOR INVESTMENT CORP ET AL | 24,100 | 102,000 | 0.13% | ||
| 44 | CITADEL ADVISORS LLC | 23,152 | 98,000 | 0.12% | ||
| 45 | DekaBank Deutsche Girozentrale | 21,500 | 91,000 | 0.12% | ||
| 46 | D.A. DAVIDSON & CO. | 21,500 | 91,000 | 0.12% | ||
| 47 | Alpine Global Management, LLC | 20,005 | 85,000 | 0.11% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 19,789 | 84,000 | 0.11% | ||
| 49 | CITIGROUP INC | 19,613 | 83,000 | 0.11% | ||
| 50 | PANAGORA ASSET MANAGEMENT INC | 13,467 | 57,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
