| 1 |
PERCEPTIVE ADVISORS LLC |
6,264,060 |
19,105,000 |
36.96% |
|
|
| 2 |
Granahan Investment Management, LLC |
1,745,604 |
5,324,000 |
10.30% |
|
|
| 3 |
Palo Alto Investors LP |
1,656,644 |
5,053,000 |
9.78% |
|
|
| 4 |
VANGUARD GROUP INC |
1,141,789 |
3,482,000 |
6.74% |
|
|
| 5 |
FMR LLC |
998,314 |
3,045,000 |
5.89% |
|
|
| 6 |
Cormorant Asset Management, LP |
850,000 |
2,593,000 |
5.02% |
|
|
| 7 |
BlackRock Fund Advisors |
700,736 |
2,137,000 |
4.13% |
|
|
| 8 |
BlackRock Institutional Trust Company, N.A. |
436,382 |
1,331,000 |
2.58% |
|
|
| 9 |
DEUTSCHE BANK AG\ |
333,560 |
1,016,000 |
1.97% |
|
|
| 10 |
Spark Investment Management LLC |
318,500 |
980,000 |
1.90% |
|
|
| 11 |
MORGAN STANLEY |
287,660 |
878,000 |
1.70% |
|
|
| 12 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
271,770 |
829,000 |
1.60% |
|
|
| 13 |
D. E. Shaw & Co., Inc. |
192,281 |
586,000 |
1.13% |
|
|
| 14 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
163,223 |
498,000 |
0.96% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
135,544 |
413,000 |
0.80% |
|
|
| 16 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
101,300 |
309,000 |
0.60% |
|
|
| 17 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
98,900 |
302,000 |
0.58% |
Call |
|
| 18 |
SABBY MANAGEMENT, LLC |
98,602 |
301,000 |
0.58% |
|
|
| 19 |
AMERICAN INTERNATIONAL GROUP, INC. |
84,253 |
257,000 |
0.50% |
|
|
| 20 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
77,500 |
236,000 |
0.46% |
Put |
|
| 21 |
SHEPHERD KAPLAN KROCHUK, LLC |
76,472 |
233,000 |
0.45% |
|
|
| 22 |
MYCIO WEALTH PARTNERS, LLC |
75,000 |
229,000 |
0.44% |
|
|
| 23 |
CITADEL ADVISORS LLC |
73,784 |
225,000 |
0.44% |
|
|
| 24 |
Joel Isaacson & Co., LLC |
70,660 |
216,000 |
0.42% |
|
|
| 25 |
MILLENNIUM MANAGEMENT LLC |
70,080 |
214,000 |
0.41% |
|
|
| 26 |
GOLDMAN SACHS GROUP INC |
67,706 |
207,000 |
0.40% |
|
|
| 27 |
Cornerstone Capital, Inc. |
59,200 |
181,000 |
0.35% |
|
|
| 28 |
Opus Point Partners Management, LLC |
57,747 |
176,000 |
0.34% |
|
|
| 29 |
Creative Planning |
44,200 |
135,000 |
0.26% |
|
|
| 30 |
NORTHERN TRUST CORP |
42,393 |
129,000 |
0.25% |
|
|
| 31 |
Bank of New York Mellon Corp |
38,402 |
117,000 |
0.23% |
|
|
| 32 |
ProShare Advisors LLC |
33,851 |
103,000 |
0.20% |
|
|
| 33 |
HIGHBRIDGE CAPITAL MANAGEMENT LLC |
32,490 |
99,000 |
0.19% |
|
|
| 34 |
D.A. DAVIDSON & CO. |
27,000 |
82,000 |
0.16% |
|
|
| 35 |
OSTERWEIS CAPITAL MANAGEMENT INC |
25,709 |
78,000 |
0.15% |
|
|
| 36 |
DekaBank Deutsche Girozentrale |
22,500 |
69,000 |
0.13% |
|
|
| 37 |
CITIGROUP INC |
19,435 |
59,000 |
0.11% |
|
|
| 38 |
BANK OF AMERICA CORP /DE/ |
17,600 |
54,000 |
0.10% |
|
|
| 39 |
STATE STREET CORP |
16,300 |
49,000 |
0.09% |
|
|
| 40 |
BARCLAYS PLC |
15,372 |
46,000 |
0.09% |
|
|
| 41 |
Virtu KCG Holdings LLC |
14,463 |
44,000 |
0.09% |
|
|
| 42 |
NOMURA HOLDINGS INC |
11,400 |
41,000 |
0.08% |
|
|
| 43 |
PANAGORA ASSET MANAGEMENT INC |
12,017 |
37,000 |
0.07% |
|
|
| 44 |
CREDIT SUISSE AG/ |
11,887 |
36,000 |
0.07% |
|
|
| 45 |
Board of Trustees of The Leland Stanford Junior University |
11,515 |
35,000 |
0.07% |
|
|
| 46 |
PNC FINANCIAL SERVICES GROUP, INC. |
8,000 |
24,000 |
0.05% |
|
|
| 47 |
BLACKROCK ADVISORS LLC |
6,998 |
21,000 |
0.04% |
|
|
| 48 |
WELLS FARGO & COMPANY/MN |
5,659 |
18,000 |
0.03% |
|
|
| 49 |
BlackRock Investment Management, LLC |
5,681 |
17,000 |
0.03% |
|
|
| 50 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
5,091 |
16,000 |
0.03% |
|
|
