| 1 |
PHARMSTANDARD INTERNATIONAL S.A. |
13,242,279 |
4,808,000 |
63.95% |
|
|
| 2 |
PHARMSTANDARD INTERNATIONAL S.A. |
5,120,604 |
1,859,000 |
24.73% |
Call |
|
| 3 |
VANGUARD GROUP INC |
780,035 |
284,000 |
3.78% |
|
|
| 4 |
Alyeska Investment Group, L.P. |
200,000 |
73,000 |
0.97% |
Call |
|
| 5 |
MILLENNIUM MANAGEMENT LLC |
193,294 |
70,000 |
0.93% |
|
|
| 6 |
SANDERS MORRIS HARRIS INC/FA |
141,212 |
52,000 |
0.69% |
|
|
| 7 |
GEODE CAPITAL MANAGEMENT, LLC |
129,046 |
46,000 |
0.61% |
|
|
| 8 |
GOLDMAN SACHS GROUP INC |
110,181 |
40,000 |
0.53% |
|
|
| 9 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
94,800 |
34,000 |
0.45% |
|
|
| 10 |
WEDBUSH SECURITIES INC |
89,500 |
32,000 |
0.43% |
|
|
| 11 |
ELEMENT CAPITAL MANAGEMENT LLC |
82,808 |
30,000 |
0.40% |
|
|
| 12 |
STIFEL FINANCIAL CORP |
65,550 |
24,000 |
0.32% |
|
|
| 13 |
MORGAN STANLEY |
53,204 |
19,000 |
0.25% |
|
|
| 14 |
Paloma Partners Management Co |
46,100 |
17,000 |
0.23% |
|
|
| 15 |
LMR Partners LLP |
45,017 |
16,000 |
0.21% |
|
|
| 16 |
NORTHERN TRUST CORP |
43,244 |
16,000 |
0.21% |
|
|
| 17 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
31,271 |
11,000 |
0.15% |
|
|
| 18 |
HighTower Advisors, LLC |
32,071 |
11,000 |
0.15% |
|
|
| 19 |
Bank of New York Mellon Corp |
25,423 |
9,000 |
0.12% |
|
|
| 20 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
22,200 |
8,000 |
0.11% |
Put |
|
| 21 |
CITADEL ADVISORS LLC |
17,989 |
7,000 |
0.09% |
|
|
| 22 |
CUTLER GROUP LLC / CA |
16,700 |
6,000 |
0.08% |
|
|
| 23 |
Squarepoint Ops LLC |
14,301 |
5,000 |
0.07% |
|
|
| 24 |
ADVISOR GROUP, INC. |
11,500 |
4,000 |
0.05% |
|
|
| 25 |
ROYAL BANK OF CANADA |
11,250 |
4,000 |
0.05% |
|
|
| 26 |
ROYAL BANK OF CANADA |
10,000 |
4,000 |
0.05% |
Put |
|
| 27 |
CITADEL ADVISORS LLC |
11,000 |
4,000 |
0.05% |
Call |
|
| 28 |
CITADEL ADVISORS LLC |
11,900 |
4,000 |
0.05% |
Put |
|
| 29 |
STATE STREET CORP |
11,900 |
4,000 |
0.05% |
|
|
| 30 |
GROUP ONE TRADING LLC |
10,810 |
4,000 |
0.05% |
|
|
| 31 |
BANK OF AMERICA CORP /DE/ |
6,306 |
2,000 |
0.03% |
|
|
| 32 |
Tower Research Capital LLC (TRC) |
4,914 |
2,000 |
0.03% |
|
|
| 33 |
BARCLAYS PLC |
6,664 |
2,000 |
0.03% |
|
|
| 34 |
Creative Planning |
6,000 |
2,000 |
0.03% |
|
|
| 35 |
BlackRock Finance, Inc. |
6,256 |
2,000 |
0.03% |
|
|
| 36 |
UBS Group AG |
4,350 |
1,000 |
0.01% |
|
|
| 37 |
MEEDER ASSET MANAGEMENT INC |
1,778 |
1,000 |
0.01% |
|
|
| 38 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
4,062 |
1,000 |
0.01% |
|
|
| 39 |
BNP PARIBAS FINANCIAL MARKETS |
4 |
1 |
0.00% |
|
|
| 40 |
CAPTRUST FINANCIAL ADVISORS |
1,000 |
0 |
0.00% |
|
|
| 41 |
CUTLER GROUP LLC / CA |
600 |
0 |
0.00% |
Call |
|
| 42 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,050 |
0 |
0.00% |
|
|
| 43 |
DEUTSCHE BANK AG\ |
736 |
0 |
0.00% |
|
|
| 44 |
CITIGROUP INC |
1 |
0 |
0.00% |
|
|
