| 1 |
Broadfin Capital, LLC |
3,100,086 |
24,987,000 |
24.51% |
|
|
| 2 |
STONEPINE CAPITAL MANAGEMENT, LLC |
2,874,317 |
23,167,000 |
22.72% |
|
|
| 3 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
2,075,000 |
16,725,000 |
16.40% |
|
|
| 4 |
Alyeska Investment Group, L.P. |
862,761 |
6,954,000 |
6.82% |
|
|
| 5 |
Tourbillon Capital Partners, L.P. |
646,552 |
5,211,000 |
5.11% |
|
|
| 6 |
Cormorant Asset Management, LP |
603,000 |
4,860,000 |
4.77% |
|
|
| 7 |
VANGUARD GROUP INC |
388,196 |
3,129,000 |
3.07% |
|
|
| 8 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
311,072 |
2,507,000 |
2.46% |
|
|
| 9 |
ACUTA CAPITAL PARTNERS, LLC |
300,000 |
2,418,000 |
2.37% |
|
|
| 10 |
BlackRock Institutional Trust Company, N.A. |
221,433 |
1,785,000 |
1.75% |
|
|
| 11 |
MARSHALL WACE, LLP |
177,923 |
1,434,000 |
1.41% |
|
|
| 12 |
Candriam S.C.A. |
150,000 |
1,209,000 |
1.19% |
|
|
| 13 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
103,616 |
835,000 |
0.82% |
|
|
| 14 |
CADENCE CAPITAL MANAGEMENT LLC |
90,066 |
726,000 |
0.71% |
|
|
| 15 |
Granite Point Capital Management, L.P. |
76,000 |
613,000 |
0.60% |
|
|
| 16 |
Numeric Investors LLC |
68,933 |
556,000 |
0.55% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
66,565 |
536,000 |
0.53% |
|
|
| 18 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
64,300 |
518,000 |
0.51% |
|
|
| 19 |
MONASHEE INVESTMENT MANAGEMENT LLC |
52,000 |
419,000 |
0.41% |
|
|
| 20 |
TRUIST FINANCIAL CORP |
50,000 |
403,000 |
0.40% |
|
|
| 21 |
MILLENNIUM MANAGEMENT LLC |
45,853 |
370,000 |
0.36% |
|
|
| 22 |
Opus Point Partners Management, LLC |
40,000 |
322,000 |
0.32% |
|
|
| 23 |
GOLDMAN SACHS GROUP INC |
36,041 |
290,000 |
0.28% |
|
|
| 24 |
Squarepoint Ops LLC |
32,800 |
264,000 |
0.26% |
|
|
| 25 |
CARL DOMINO INC |
30,024 |
242,000 |
0.24% |
|
|
| 26 |
PRELUDE CAPITAL MANAGEMENT, LLC |
20,879 |
168,000 |
0.16% |
|
|
| 27 |
ALAMBIC INVESTMENT MANAGEMENT, L.P. |
19,166 |
154,000 |
0.15% |
|
|
| 28 |
BlackRock Fund Advisors |
18,677 |
151,000 |
0.15% |
|
|
| 29 |
RENAISSANCE TECHNOLOGIES LLC |
18,400 |
148,000 |
0.15% |
|
|
| 30 |
WELLS FARGO & COMPANY/MN |
16,700 |
135,000 |
0.13% |
|
|
| 31 |
NORTHERN TRUST CORP |
16,213 |
130,000 |
0.13% |
|
|
| 32 |
DIMENSIONAL FUND ADVISORS LP |
14,600 |
118,000 |
0.12% |
|
|
| 33 |
Trexquant Investment LP |
11,076 |
89,000 |
0.09% |
|
|
| 34 |
Janney Montgomery Scott LLC |
10,600 |
85,000 |
0.08% |
|
|
| 35 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
8,820 |
71,000 |
0.07% |
|
|
| 36 |
MORGAN STANLEY |
7,925 |
64,000 |
0.06% |
|
|
| 37 |
STEELHEAD PARTNERS LLC |
4,000 |
32,000 |
0.03% |
|
|
| 38 |
Segantii Capital Management Ltd |
3,800 |
31,000 |
0.03% |
|
|
| 39 |
PANAGORA ASSET MANAGEMENT INC |
3,428 |
28,000 |
0.03% |
|
|
| 40 |
BLACKROCK ADVISORS LLC |
2,418 |
19,000 |
0.02% |
|
|
| 41 |
BARCLAYS PLC |
2,278 |
18,000 |
0.02% |
|
|
| 42 |
BlackRock Investment Management, LLC |
1,311 |
11,000 |
0.01% |
|
|
| 43 |
UBS Group AG |
812 |
7,000 |
0.01% |
|
|
| 44 |
GLEN EAGLE ADVISORS, LLC |
575 |
4,635 |
0.00% |
|
|
| 45 |
Creative Planning |
500 |
4,000 |
0.00% |
|
|
| 46 |
Tower Research Capital LLC (TRC) |
500 |
4,000 |
0.00% |
|
|
| 47 |
Walleye Trading LLC |
418 |
3,000 |
0.00% |
|
|
| 48 |
MUFG Americas Holdings Corp |
185 |
1,000 |
0.00% |
|
|
| 49 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
115 |
1,000 |
0.00% |
|
|
| 50 |
GLOBEFLEX CAPITAL L P |
101 |
1,000 |
0.00% |
|
|
