| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 4,688,794 | 22,459,000 | 10.28% | ||
| 2 | FEDERATED HERMES, INC. | 2,960,554 | 14,181,000 | 6.49% | ||
| 3 | FMR LLC | 2,703,352 | 12,949,000 | 5.93% | ||
| 4 | ARMISTICE CAPITAL, LLC | 2,620,000 | 12,550,000 | 5.75% | ||
| 5 | VANGUARD GROUP INC | 1,855,176 | 8,887,000 | 4.07% | ||
| 6 | FALCON POINT CAPITAL, LLC | 1,848,577 | 8,855,000 | 4.05% | ||
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 1,776,208 | 8,508,000 | 3.90% | ||
| 8 | ROYCE & ASSOCIATES LP | 1,487,800 | 7,127,000 | 3.26% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,411,063 | 6,759,000 | 3.09% | ||
| 10 | Penn Capital Management Company, LLC | 1,314,623 | 6,297,000 | 2.88% | ||
| 11 | BlackRock Fund Advisors | 1,254,503 | 6,009,000 | 2.75% | ||
| 12 | RUSSELL FRANK CO/ | 1,080,051 | 5,151,000 | 2.36% | ||
| 13 | Foresite Capital Management II, LLC | 947,815 | 4,540,000 | 2.08% | ||
| 14 | TURNER INVESTMENTS LLC | 900,830 | 4,315,000 | 1.98% | ||
| 15 | Grandeur Peak Global Advisors, LLC | 896,881 | 4,296,000 | 1.97% | ||
| 16 | BANK OF MONTREAL /CAN/ | 829,056 | 3,971,000 | 1.82% | ||
| 17 | CITADEL ADVISORS LLC | 770,196 | 3,689,000 | 1.69% | ||
| 18 | Granahan Investment Management, LLC | 740,630 | 3,548,000 | 1.62% | ||
| 19 | Lombard Odier Asset Management (USA) Corp | 702,486 | 3,365,000 | 1.54% | ||
| 20 | STATE STREET CORP | 682,462 | 3,269,000 | 1.50% | ||
| 21 | SABBY MANAGEMENT, LLC | 617,496 | 2,958,000 | 1.35% | ||
| 22 | BLAIR WILLIAM & CO/IL | 570,903 | 2,734,000 | 1.25% | ||
| 23 | NORTHERN TRUST CORP | 559,766 | 2,681,000 | 1.23% | ||
| 24 | TIVERTON ASSET MANAGEMENT LLC | 550,000 | 2,635,000 | 1.21% | ||
| 25 | 1492 Capital Management LLC | 538,538 | 2,580,000 | 1.18% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 505,300 | 2,420,000 | 1.11% | Put | |
| 27 | Broadfin Capital, LLC | 500,000 | 2,395,000 | 1.10% | Call | |
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 473,362 | 2,267,000 | 1.04% | ||
| 29 | NEW YORK STATE COMMON RETIREMENT FUND | 460,608 | 2,206,000 | 1.01% | ||
| 30 | EverPoint Asset Management, LLC | 435,585 | 2,086,000 | 0.96% | ||
| 31 | SUFFOLK CAPITAL MANAGEMENT LLC | 366,594 | 1,756,000 | 0.80% | ||
| 32 | A.R.T. Advisors, LLC | 346,535 | 1,659,000 | 0.76% | ||
| 33 | SEI INVESTMENTS CO | 330,789 | 1,584,000 | 0.73% | ||
| 34 | Foresite Capital Management II, LLC | 310,000 | 1,485,000 | 0.68% | Call | |
| 35 | SHEPHERD KAPLAN KROCHUK, LLC | 297,445 | 1,425,000 | 0.65% | ||
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 296,716 | 1,421,000 | 0.65% | ||
| 37 | JPMORGAN CHASE & CO | 279,000 | 1,336,000 | 0.61% | ||
| 38 | Endurant Capital Management LP | 278,380 | 1,333,000 | 0.61% | ||
| 39 | Jefferies Group LLC | 250,000 | 1,198,000 | 0.55% | Put | |
| 40 | Jefferies Group LLC | 250,000 | 1,198,000 | 0.55% | Call | |
| 41 | RENAISSANCE TECHNOLOGIES LLC | 234,100 | 1,121,000 | 0.51% | ||
| 42 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 229,400 | 1,099,000 | 0.50% | ||
| 43 | Bank of New York Mellon Corp | 213,726 | 1,024,000 | 0.47% | ||
| 44 | PANAGORA ASSET MANAGEMENT INC | 210,336 | 1,008,000 | 0.46% | ||
| 45 | BAKER BROS. ADVISORS LP | 210,021 | 1,006,000 | 0.46% | ||
| 46 | Foresite Capital Management II, LLC | 210,000 | 1,006,000 | 0.46% | Put | |
| 47 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 183,165 | 877,000 | 0.40% | ||
| 48 | MILLENNIUM MANAGEMENT LLC | 170,306 | 816,000 | 0.37% | ||
| 49 | BlackRock Investment Management, LLC | 168,253 | 806,000 | 0.37% | ||
| 50 | SEARLE & CO. | 174,250 | 789,000 | 0.36% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
