| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SEATTLE GENETICS INC | 44,100,294 | 2,381,857,000 | 21.61% | ||
| 2 | INCYTE | 23,498,898 | 2,215,711,000 | 20.11% | ||
| 3 | ABBVIE INC | 14,343,358 | 904,636,000 | 8.21% | ||
| 4 | ACADIA PHARMACEUTICALS INC COM | 25,819,768 | 821,327,000 | 7.45% | ||
| 5 | ALEXION PHARMACEUTIC | 6,543,295 | 801,815,000 | 7.28% | ||
| 6 | Incyte Corporation | 274,500,000 | 531,244,000 | 4.82% | PRN | |
| 7 | Incyte Corporation | 259,000,000 | 491,344,000 | 4.46% | PRN | |
| 8 | BIOMARIN | 4,806,483 | 444,696,000 | 4.04% | ||
| 9 | GENOMIC HEALTH INC COM | 13,770,302 | 398,237,000 | 3.61% | ||
| 10 | DBV TECHNOLOGIES | 5,509,560 | 200,162,000 | 1.82% | ||
| 11 | Aquinox Pharmaceuticals Inc | 10,536,092 | 140,762,000 | 1.28% | ||
| 12 | BIOMARIN PHARMACEUTICAL INC | 22,379,000 | 101,405,000 | 0.92% | PRN | |
| 13 | BELLICUM PHARMACEUTICALS INC COM | 4,865,647 | 96,826,000 | 0.88% | ||
| 14 | CERUS CORP | 13,053,275 | 81,061,000 | 0.74% | ||
| 15 | SPARK THERAPEUTICS INC | 1,318,341 | 79,180,000 | 0.72% | ||
| 16 | ACORDA THERAPEUTICS | 3,661,082 | 76,443,000 | 0.69% | ||
| 17 | CLOVIS ONCOLOGY INC NOTE | 72,758,000 | 69,135,000 | 0.63% | PRN | |
| 18 | AMARIN CORP PLC | 20,630,477 | 65,811,000 | 0.60% | ||
| 19 | EXELIXIS INC | 4,929,494 | 63,048,000 | 0.57% | ||
| 20 | ACORDA THERAPEUTICS INC | 77,083,000 | 62,830,000 | 0.57% | PRN | |
| 21 | BEIGENE LTD | 1,912,680 | 58,930,000 | 0.53% | ||
| 22 | INVITAE CORP | 6,554,967 | 57,422,000 | 0.52% | ||
| 23 | HERON THERAPEUTICS INC | 2,857,250 | 49,230,000 | 0.45% | ||
| 24 | BIOCRYST PHARMACEUTICALS | 10,963,944 | 48,351,000 | 0.44% | ||
| 25 | NEUROCRINE BIOSCIE COM USD0.001 | 895,422 | 45,344,000 | 0.41% | ||
| 26 | ADVANCED ACCELERATOR APPLIC | 1,029,247 | 39,194,000 | 0.36% | ||
| 27 | VERSARTIS INC COM | 2,134,247 | 26,145,000 | 0.24% | ||
| 28 | PROGENICS PHARMACEUTICALS IN | 3,650,808 | 23,110,000 | 0.21% | ||
| 29 | Foamix Pharmaceuticals Ltd. | 2,466,702 | 22,842,000 | 0.21% | ||
| 30 | ARRAY BIOPHARMA INC COM | 3,310,666 | 22,347,000 | 0.20% | ||
| 31 | XENCOR INC COM | 872,072 | 21,357,000 | 0.19% | ||
| 32 | HALOZYME THERAPEUTICS INC | 1,731,057 | 20,911,000 | 0.19% | ||
| 33 | ACHILLION PHARMACEUTICALS INC COM | 2,475,515 | 20,052,000 | 0.18% | ||
| 34 | BLUEBIRD BIO INCORPORATED | 293,943 | 19,923,000 | 0.18% | ||
| 35 | MERUS N V | 1,160,014 | 19,430,000 | 0.18% | ||
| 36 | SANGAMO BIOSCIENCES INCORPORATED | 4,055,876 | 18,779,000 | 0.17% | ||
| 37 | INTELLIA THERAPEUTICS INC | 1,062,120 | 18,077,000 | 0.16% | ||
| 38 | IDERA PHARMACEUTICALS INC | 7,014,015 | 17,956,000 | 0.16% | ||
| 39 | DERMA SCIENCES INC COM PAR .01 | 3,752,390 | 17,524,000 | 0.16% | ||
| 40 | AEGERION PHARMACEUTICALS INC | 26,517,000 | 17,432,000 | 0.16% | PRN | |
| 41 | GALAPAGOS NV | 259,894 | 16,805,000 | 0.15% | ||
| 42 | TG THERAPEUTICS INC COM | 2,003,991 | 15,511,000 | 0.14% | ||
| 43 | MIRATI THERAPEUTICS INC COM | 2,269,198 | 14,999,000 | 0.14% | ||
| 44 | Ascendis Pharma | 745,521 | 14,985,000 | 0.14% | ||
| 45 | BIOMARIN PHARMACEUTICAL INC | 12,228,000 | 14,630,000 | 0.13% | PRN | |
| 46 | ARROWHEAD PHARMACEUTICALS IN | 1,856,967 | 13,649,000 | 0.12% | ||
| 47 | VITAE PHARMACEUTICALS INC | 637,597 | 13,339,000 | 0.12% | ||
| 48 | ALKERMES PLC SHS | 250,251 | 11,769,000 | 0.11% | ||
| 49 | ZOGENIX INC | 1,000,000 | 11,430,000 | 0.10% | ||
| 50 | AERIE PHARMACEUTICALS INC | 299,356 | 11,298,000 | 0.10% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-134352, filed 2016.11.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
