| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BlackRock Finance, Inc. | 2,198,197 | 79,092,000 | 17.34% | ||
| 2 | Krensavage Asset Management, LLC | 1,104,992 | 39,758,000 | 8.72% | ||
| 3 | FIRST MANHATTAN CO. LLC. | 934,700 | 33,630,000 | 7.37% | ||
| 4 | VANGUARD GROUP INC | 847,021 | 30,475,000 | 6.68% | ||
| 5 | STATE STREET CORP | 686,047 | 24,686,000 | 5.41% | ||
| 6 | RENAISSANCE TECHNOLOGIES LLC | 620,500 | 22,326,000 | 4.89% | ||
| 7 | DIMENSIONAL FUND ADVISORS LP | 554,777 | 19,961,000 | 4.38% | ||
| 8 | STONEPINE CAPITAL MANAGEMENT, LLC | 492,265 | 17,712,000 | 3.88% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 487,405 | 17,537,000 | 3.84% | ||
| 10 | Candriam S.C.A. | 310,000 | 11,154,000 | 2.44% | ||
| 11 | FMR LLC | 276,815 | 9,960,000 | 2.18% | ||
| 12 | Matarin Capital Management, LLC | 274,893 | 9,890,650 | 2.17% | ||
| 13 | ARMISTICE CAPITAL, LLC | 264,000 | 9,499,000 | 2.08% | ||
| 14 | Ghost Tree Capital, LLC | 200,000 | 7,196,000 | 1.58% | ||
| 15 | NORTHERN TRUST CORP | 195,712 | 7,041,000 | 1.54% | ||
| 16 | Bank of New York Mellon Corp | 191,982 | 6,907,000 | 1.51% | ||
| 17 | Granahan Investment Management, LLC | 151,695 | 5,458,000 | 1.20% | ||
| 18 | JPMORGAN CHASE & CO | 138,890 | 4,997,000 | 1.10% | ||
| 19 | AQR CAPITAL MANAGEMENT LLC | 137,723 | 4,955,000 | 1.09% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 136,420 | 4,908,000 | 1.08% | ||
| 21 | AMERIPRISE FINANCIAL INC | 116,475 | 4,190,000 | 0.92% | ||
| 22 | PRINCIPAL FINANCIAL GROUP INC | 106,253 | 3,823,000 | 0.84% | ||
| 23 | Opaleye Management Inc. | 100,000 | 3,598,000 | 0.79% | ||
| 24 | ING GROEP NV | 91,000 | 3,274,000 | 0.72% | ||
| 25 | GOLDMAN SACHS GROUP INC | 83,704 | 3,012,000 | 0.66% | ||
| 26 | Invesco Ltd. | 81,137 | 2,920,000 | 0.64% | ||
| 27 | QS Investors, LLC | 77,792 | 2,799,000 | 0.61% | ||
| 28 | Numeric Investors LLC | 76,602 | 2,756,000 | 0.60% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 71,815 | 2,584,000 | 0.57% | ||
| 30 | ALLIANCEBERNSTEIN L.P. | 69,820 | 2,512,000 | 0.55% | ||
| 31 | PNC FINANCIAL SERVICES GROUP, INC. | 68,703 | 2,472,000 | 0.54% | ||
| 32 | VIRGINIA RETIREMENT SYSTEMS ET Al | 65,900 | 2,371,000 | 0.52% | ||
| 33 | McClain Value Management LLC | 65,295 | 2,349,000 | 0.51% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 53,616 | 1,930,000 | 0.42% | ||
| 35 | Spark Investment Management LLC | 53,100 | 1,910,000 | 0.42% | ||
| 36 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 47,800 | 1,720,000 | 0.38% | ||
| 37 | PRUDENTIAL FINANCIAL INC | 46,107 | 1,659,000 | 0.36% | ||
| 38 | TWO SIGMA INVESTMENTS, LP | 45,876 | 1,651,000 | 0.36% | ||
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 42,951 | 1,545,000 | 0.34% | ||
| 40 | Compagnie Lombard Odier SCmA | 42,000 | 1,512,000 | 0.33% | ||
| 41 | D. E. Shaw & Co., Inc. | 38,736 | 1,394,000 | 0.31% | ||
| 42 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 38,190 | 1,374,000 | 0.30% | ||
| 43 | NEW YORK STATE COMMON RETIREMENT FUND | 37,078 | 1,334,000 | 0.29% | ||
| 44 | AlphaMark Advisors, LLC | 33,000 | 1,187,000 | 0.26% | SH | |
| 45 | VIRTUS ETF ADVISERS LLC | 32,235 | 1,160,000 | 0.25% | ||
| 46 | Freedom Investment Management, Inc. | 31,565 | 1,136,000 | 0.25% | ||
| 47 | RHUMBLINE ADVISERS | 31,129 | 1,120,000 | 0.25% | ||
| 48 | MORGAN STANLEY | 30,840 | 1,110,000 | 0.24% | ||
| 49 | CITIGROUP INC | 30,515 | 1,098,000 | 0.24% | ||
| 50 | Weiss Multi-Strategy Advisers LLC | 30,000 | 1,079,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
