| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Aisling Capital LLC | 2,054,594 | 83,088,000 | 20.67% | ||
| 2 | Pentwater Capital Management LP | 1,470,000 | 59,447,000 | 14.79% | ||
| 3 | FMR LLC | 1,401,274 | 56,668,000 | 14.09% | ||
| 4 | WASATCH ADVISORS LP | 1,002,722 | 40,550,000 | 10.09% | ||
| 5 | Polar Capital LLP | 528,598 | 21,375,000 | 5.32% | ||
| 6 | PERCEPTIVE ADVISORS LLC | 302,500 | 12,233,000 | 3.04% | ||
| 7 | VANGUARD GROUP INC | 249,618 | 10,095,000 | 2.51% | ||
| 8 | Visium Asset Management, LP | 200,000 | 8,088,000 | 2.01% | ||
| 9 | Iguana Healthcare Management, LLC | 200,000 | 8,088,000 | 2.01% | ||
| 10 | Informed Momentum Co LLC | 184,020 | 7,442,000 | 1.85% | ||
| 11 | BlackRock Fund Advisors | 174,651 | 7,063,000 | 1.76% | ||
| 12 | Rhenman & Partners Asset Management AB | 150,000 | 6,066,000 | 1.51% | ||
| 13 | DEUTSCHE BANK AG\ | 142,683 | 5,769,000 | 1.43% | ||
| 14 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 121,326 | 4,906,000 | 1.22% | ||
| 15 | MORGAN STANLEY | 99,984 | 4,044,000 | 1.01% | ||
| 16 | Bank of New York Mellon Corp | 93,134 | 3,766,000 | 0.94% | ||
| 17 | AXA S.A. | 88,546 | 3,581,000 | 0.89% | ||
| 18 | BlackRock Institutional Trust Company, N.A. | 86,830 | 3,511,000 | 0.87% | ||
| 19 | STATE STREET CORP | 75,926 | 3,068,000 | 0.76% | ||
| 20 | EverPoint Asset Management, LLC | 75,000 | 3,033,000 | 0.75% | ||
| 21 | NORTHERN TRUST CORP | 67,214 | 2,718,000 | 0.68% | ||
| 22 | RUSSELL FRANK CO/ | 67,257 | 2,713,000 | 0.67% | ||
| 23 | Weiss Multi-Strategy Advisers LLC | 60,000 | 2,426,000 | 0.60% | Call | |
| 24 | Candriam S.C.A. | 55,000 | 2,224,000 | 0.55% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 53,923 | 2,180,000 | 0.54% | ||
| 26 | Sio Capital Management, LLC | 53,600 | 2,168,000 | 0.54% | ||
| 27 | ALLIANCEBERNSTEIN L.P. | 46,230 | 1,870,000 | 0.47% | ||
| 28 | Nicholas Investment Partners, LP | 40,104 | 1,622,000 | 0.40% | ||
| 29 | Weiss Multi-Strategy Advisers LLC | 40,000 | 1,618,000 | 0.40% | ||
| 30 | AMERIPRISE FINANCIAL INC | 39,648 | 1,603,000 | 0.40% | ||
| 31 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 33,547 | 1,581,000 | 0.39% | ||
| 32 | TWO SIGMA INVESTMENTS, LP | 38,250 | 1,547,000 | 0.38% | ||
| 33 | BAMCO INC /NY/ | 35,200 | 1,423,000 | 0.35% | ||
| 34 | Allianz Asset Management GmbH | 34,567 | 1,398,000 | 0.35% | ||
| 35 | A.R.T. Advisors, LLC | 34,441 | 1,392,000 | 0.35% | ||
| 36 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 32,736 | 1,324,000 | 0.33% | ||
| 37 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 32,200 | 1,302,000 | 0.32% | ||
| 38 | GILDER GAGNON HOWE & CO LLC | 30,401 | 1,229,000 | 0.31% | ||
| 39 | Jefferies Group LLC | 30,000 | 1,213,000 | 0.30% | Put | |
| 40 | Geduld E E | 30,000 | 1,213,000 | 0.30% | ||
| 41 | Invesco Ltd. | 29,145 | 1,179,000 | 0.29% | ||
| 42 | STIFEL FINANCIAL CORP | 26,850 | 1,082,000 | 0.27% | ||
| 43 | CREDIT SUISSE AG/ | 19,630 | 794,000 | 0.20% | ||
| 44 | TIAA CREF INVESTMENT MANAGEMENT LLC | 19,609 | 793,000 | 0.20% | ||
| 45 | ROYAL BANK OF CANADA | 19,600 | 792,000 | 0.20% | ||
| 46 | CITIGROUP INC | 17,496 | 708,000 | 0.18% | ||
| 47 | BlackRock Investment Management, LLC | 17,106 | 692,000 | 0.17% | ||
| 48 | Quantitative Systematic Strategies LLC | 14,772 | 579,000 | 0.14% | ||
| 49 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 13,200 | 534,000 | 0.13% | Put | |
| 50 | Paloma Partners Management Co | 12,991 | 525,000 | 0.13% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
