| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Aisling Capital LLC | 1,637,125 | 16,175,000 | 10.76% | ||
| 2 | Pentwater Capital Management LP | 1,518,000 | 14,998,000 | 9.98% | ||
| 3 | FMR LLC | 1,068,950 | 10,561,000 | 7.02% | ||
| 4 | DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 1,050,000 | 10,374,000 | 6.90% | ||
| 5 | BB BIOTECH AG | 1,008,542 | 9,964,000 | 6.63% | ||
| 6 | VOYA INVESTMENT MANAGEMENT LLC | 931,360 | 9,202,000 | 6.12% | ||
| 7 | VANGUARD GROUP INC | 811,704 | 8,020,000 | 5.33% | ||
| 8 | BlackRock Fund Advisors | 657,919 | 6,500,000 | 4.32% | ||
| 9 | WASATCH ADVISORS LP | 533,774 | 5,274,000 | 3.51% | ||
| 10 | BVF INC/IL | 499,142 | 4,932,000 | 3.28% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 352,706 | 3,485,000 | 2.32% | ||
| 12 | NORTHERN TRUST CORP | 335,886 | 3,319,000 | 2.21% | ||
| 13 | TIVERTON ASSET MANAGEMENT LLC | 56,063 | 2,938,000 | 1.95% | ||
| 14 | CREDIT SUISSE AG/ | 297,024 | 2,935,000 | 1.95% | ||
| 15 | Granahan Investment Management, LLC | 248,030 | 2,451,000 | 1.63% | ||
| 16 | STATE STREET CORP | 246,271 | 2,438,000 | 1.62% | ||
| 17 | OXFORD ASSET MANAGEMENT LLP | 236,943 | 2,341,000 | 1.56% | ||
| 18 | DEUTSCHE BANK AG\ | 222,867 | 2,200,000 | 1.46% | ||
| 19 | SENZAR ASSET MANAGEMENT, LLC | 219,743 | 2,171,061 | 1.44% | ||
| 20 | FNY Managed Accounts LLC | 200,000 | 1,976,000 | 1.31% | ||
| 21 | Invesco Ltd. | 176,229 | 1,742,000 | 1.16% | ||
| 22 | JPMORGAN CHASE & CO | 142,161 | 1,404,000 | 0.93% | ||
| 23 | Rhenman & Partners Asset Management AB | 140,000 | 1,383,000 | 0.92% | ||
| 24 | GAM Holding AG | 128,000 | 1,265,000 | 0.84% | ||
| 25 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 128,000 | 1,265,000 | 0.84% | Put | |
| 26 | MORGAN STANLEY | 126,530 | 1,250,000 | 0.83% | ||
| 27 | GEODE CAPITAL MANAGEMENT, LLC | 109,473 | 1,081,000 | 0.72% | ||
| 28 | BANK OF AMERICA CORP /DE/ | 108,381 | 1,071,000 | 0.71% | ||
| 29 | Tekla Capital Management LLC | 102,800 | 1,016,000 | 0.68% | ||
| 30 | PAULSON & CO. INC. | 102,000 | 1,008,000 | 0.67% | ||
| 31 | PRICE T ROWE ASSOCIATES INC /MD/ | 96,040 | 949,000 | 0.63% | ||
| 32 | FT OPTIONS LLC | 80,799 | 798,000 | 0.53% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 71,500 | 706,000 | 0.47% | Call | |
| 34 | Bank of New York Mellon Corp | 62,218 | 615,000 | 0.41% | ||
| 35 | BlackRock Investment Management, LLC | 60,234 | 595,000 | 0.40% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 56,644 | 560,000 | 0.37% | ||
| 37 | Candriam S.C.A. | 50,000 | 494,000 | 0.33% | ||
| 38 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 49,300 | 487,000 | 0.32% | ||
| 39 | GOLDMAN SACHS GROUP INC | 48,012 | 474,000 | 0.32% | ||
| 40 | TIAA CREF INVESTMENT MANAGEMENT LLC | 45,305 | 448,000 | 0.30% | ||
| 41 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 42,903 | 424,000 | 0.28% | ||
| 42 | Virtu KCG Holdings LLC | 41,780 | 413,000 | 0.27% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 41,444 | 410,000 | 0.27% | ||
| 44 | BELLEVUE GROUP AG | 40,000 | 395,000 | 0.26% | ||
| 45 | Glacier Peak Capital LLC | 38,048 | 376,000 | 0.25% | ||
| 46 | Nationwide Fund Advisors | 35,864 | 354,000 | 0.24% | ||
| 47 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 35,280 | 349,000 | 0.23% | ||
| 48 | FEDERATED HERMES, INC. | 35,219 | 348,000 | 0.23% | ||
| 49 | ALLIANCEBERNSTEIN L.P. | 31,270 | 309,000 | 0.21% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 30,016 | 297,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
