| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Pentwater Capital Management LP | 1,828,000 | 22,887,000 | 12.08% | ||
| 2 | Aisling Capital LLC | 1,637,125 | 20,497,000 | 10.82% | ||
| 3 | BB BIOTECH AG | 1,308,542 | 16,383,000 | 8.65% | ||
| 4 | DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 1,042,046 | 13,046,000 | 6.89% | ||
| 5 | BlackRock Fund Advisors | 789,210 | 9,881,000 | 5.21% | ||
| 6 | FMR LLC | 766,009 | 9,590,000 | 5.06% | ||
| 7 | BVF INC/IL | 712,770 | 8,924,000 | 4.71% | ||
| 8 | CREDIT SUISSE AG/ | 695,384 | 8,706,000 | 4.59% | ||
| 9 | VANGUARD GROUP INC | 600,832 | 7,522,000 | 3.97% | ||
| 10 | WASATCH ADVISORS LP | 538,194 | 6,738,000 | 3.56% | ||
| 11 | NORTHERN TRUST CORP | 506,512 | 6,341,000 | 3.35% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 398,499 | 4,989,000 | 2.63% | ||
| 13 | SENZAR ASSET MANAGEMENT, LLC | 364,000 | 4,557,000 | 2.40% | ||
| 14 | Rhenman & Partners Asset Management AB | 275,000 | 3,443,000 | 1.82% | ||
| 15 | Granahan Investment Management, LLC | 248,030 | 3,105,000 | 1.64% | ||
| 16 | KENNEDY CAPITAL MANAGEMENT LLC | 239,054 | 2,993,000 | 1.58% | ||
| 17 | STATE STREET CORP | 238,482 | 2,989,000 | 1.58% | ||
| 18 | JPMORGAN CHASE & CO | 196,500 | 2,460,000 | 1.30% | ||
| 19 | J. Goldman & Co LP | 162,000 | 2,028,000 | 1.07% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 150,000 | 1,878,000 | 0.99% | Call | |
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 129,084 | 1,616,000 | 0.85% | ||
| 22 | DEUTSCHE BANK AG\ | 121,060 | 1,514,000 | 0.80% | ||
| 23 | PINNACLE ASSOCIATES LTD | 116,480 | 1,458,000 | 0.77% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 110,523 | 1,384,000 | 0.73% | ||
| 25 | Tekla Capital Management LLC | 102,800 | 1,287,000 | 0.68% | ||
| 26 | PAULSON & CO. INC. | 102,000 | 1,277,000 | 0.67% | ||
| 27 | PRICE T ROWE ASSOCIATES INC /MD/ | 97,617 | 1,222,000 | 0.64% | ||
| 28 | Bank of New York Mellon Corp | 80,863 | 1,012,000 | 0.53% | ||
| 29 | MORGAN STANLEY | 80,086 | 1,003,000 | 0.53% | ||
| 30 | Quantitative Investment Management, LLC | 71,900 | 900,000 | 0.47% | ||
| 31 | GAM Holding AG | 64,000 | 801,000 | 0.42% | ||
| 32 | BlackRock Investment Management, LLC | 59,959 | 751,000 | 0.40% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 57,200 | 716,000 | 0.38% | Call | |
| 34 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 29,555 | 666,000 | 0.35% | ||
| 35 | MARTINGALE ASSET MANAGEMENT L P | 50,711 | 635,000 | 0.34% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 49,983 | 626,000 | 0.33% | ||
| 37 | UBS Group AG | 48,419 | 606,000 | 0.32% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 45,651 | 572,000 | 0.30% | ||
| 39 | PDT Partners, LLC | 44,900 | 562,000 | 0.30% | ||
| 40 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 43,800 | 548,000 | 0.29% | ||
| 41 | GOLDMAN SACHS GROUP INC | 42,229 | 529,000 | 0.28% | ||
| 42 | DIMENSIONAL FUND ADVISORS LP | 40,220 | 504,000 | 0.27% | ||
| 43 | BELLEVUE GROUP AG | 40,000 | 501,000 | 0.26% | ||
| 44 | TIAA CREF INVESTMENT MANAGEMENT LLC | 38,910 | 487,000 | 0.26% | ||
| 45 | Nationwide Fund Advisors | 38,365 | 480,000 | 0.25% | ||
| 46 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 35,280 | 442,000 | 0.23% | ||
| 47 | TEACHERS ADVISORS, LLC | 33,502 | 419,000 | 0.22% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 31,270 | 392,000 | 0.21% | ||
| 49 | OXFORD ASSET MANAGEMENT LLP | 29,651 | 371,000 | 0.20% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 29,416 | 368,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
