| 1 |
Polaris Venture Management Co. V, L.L.C. |
3,287,529 |
6,970,000 |
31.25% |
|
|
| 2 |
FMR LLC |
1,839,224 |
3,899,000 |
17.48% |
|
|
| 3 |
Polaris Venture Management Co IV LLC |
1,437,441 |
3,047,000 |
13.66% |
|
|
| 4 |
Granahan Investment Management, LLC |
708,215 |
1,501,000 |
6.73% |
|
|
| 5 |
Rock Springs Capital Management LP |
625,000 |
1,325,000 |
5.94% |
|
|
| 6 |
VANGUARD GROUP INC |
542,631 |
1,151,000 |
5.16% |
|
|
| 7 |
SPHERA FUNDS MANAGEMENT LTD. |
450,000 |
954,000 |
4.28% |
|
|
| 8 |
PRINCIPAL FINANCIAL GROUP INC |
357,100 |
757,000 |
3.39% |
|
|
| 9 |
Alyeska Investment Group, L.P. |
319,289 |
677,000 |
3.04% |
|
|
| 10 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
202,623 |
430,000 |
1.93% |
|
|
| 11 |
Deer VII & Co. Ltd. |
166,675 |
353,000 |
1.58% |
|
|
| 12 |
BLACKROCK ADVISORS LLC |
154,819 |
328,000 |
1.47% |
|
|
| 13 |
GEODE CAPITAL MANAGEMENT, LLC |
88,462 |
187,000 |
0.84% |
|
|
| 14 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
88,412 |
187,000 |
0.84% |
|
|
| 15 |
RENAISSANCE TECHNOLOGIES LLC |
64,700 |
137,000 |
0.61% |
|
|
| 16 |
BlackRock Fund Advisors |
42,830 |
91,000 |
0.41% |
|
|
| 17 |
Northeast Financial Consultants Inc |
20,000 |
42,000 |
0.19% |
|
|
| 18 |
WEDBUSH SECURITIES INC |
16,000 |
34,000 |
0.15% |
|
|
| 19 |
CITADEL ADVISORS LLC |
16,000 |
34,000 |
0.15% |
|
|
| 20 |
Commonwealth Equity Services, Inc |
15,713 |
33,000 |
0.15% |
|
|
| 21 |
A.R.T. Advisors, LLC |
13,826 |
29,000 |
0.13% |
|
|
| 22 |
NORTHERN TRUST CORP |
12,523 |
27,000 |
0.12% |
|
|
| 23 |
Bank of New York Mellon Corp |
12,153 |
26,000 |
0.12% |
|
|
| 24 |
MILLENNIUM MANAGEMENT LLC |
10,782 |
23,000 |
0.10% |
|
|
| 25 |
UBS Group AG |
5,887 |
12,000 |
0.05% |
|
|
| 26 |
ROYAL BANK OF CANADA |
5,300 |
11,000 |
0.05% |
|
|
| 27 |
BANK OF AMERICA CORP /DE/ |
3,867 |
8,000 |
0.04% |
|
|
| 28 |
BlackRock Group LTD |
3,856 |
8,000 |
0.04% |
|
|
| 29 |
MORGAN STANLEY |
3,001 |
7,000 |
0.03% |
|
|
| 30 |
Tower Research Capital LLC (TRC) |
2,763 |
6,000 |
0.03% |
|
|
| 31 |
BlackRock Investment Management, LLC |
3,013 |
6,000 |
0.03% |
|
|
| 32 |
DEUTSCHE BANK AG\ |
2,000 |
4,000 |
0.02% |
|
|
| 33 |
WOLVERINE TRADING LP /BD |
391 |
817 |
0.00% |
|
|
| 34 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
193 |
0 |
0.00% |
|
|
| 35 |
REILLY FINANCIAL ADVISORS, LLC |
200 |
0 |
0.00% |
|
|
