| 1 |
GOLDMAN SACHS GROUP INC |
3,457,240 |
62,541,000 |
27.64% |
|
|
| 2 |
Aisling Capital LLC |
2,523,300 |
45,650,000 |
20.17% |
|
|
| 3 |
Polaris Venture Management Co. V, L.L.C. |
2,374,571 |
42,956,000 |
18.98% |
|
|
| 4 |
GILDER GAGNON HOWE & CO LLC |
1,252,683 |
22,661,000 |
10.01% |
|
|
| 5 |
FMR LLC |
941,300 |
17,028,000 |
7.53% |
|
|
| 6 |
WELLINGTON MANAGEMENT GROUP LLP |
597,470 |
10,808,000 |
4.78% |
|
|
| 7 |
Harvest Capital Strategies LLC |
304,103 |
5,501,000 |
2.43% |
|
|
| 8 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
151,330 |
2,738,000 |
1.21% |
|
|
| 9 |
BlackRock Fund Advisors |
147,212 |
2,663,000 |
1.18% |
|
|
| 10 |
RA CAPITAL MANAGEMENT, L.P. |
138,002 |
2,496,000 |
1.10% |
|
|
| 11 |
VANGUARD GROUP INC |
132,078 |
2,390,000 |
1.06% |
|
|
| 12 |
SABBY MANAGEMENT, LLC |
105,367 |
1,906,000 |
0.84% |
|
|
| 13 |
TIGER MANAGEMENT L.L.C. |
90,909 |
1,645,000 |
0.73% |
|
|
| 14 |
BlackRock Institutional Trust Company, N.A. |
63,616 |
1,151,000 |
0.51% |
|
|
| 15 |
STATE STREET CORP |
39,600 |
715,000 |
0.32% |
|
|
| 16 |
GEODE CAPITAL MANAGEMENT, LLC |
27,025 |
488,000 |
0.22% |
|
|
| 17 |
MORGAN STANLEY |
25,200 |
456,000 |
0.20% |
|
|
| 18 |
BlackRock Investment Management, LLC |
16,766 |
303,000 |
0.13% |
|
|
| 19 |
Spark Investment Management LLC |
15,600 |
284,000 |
0.13% |
|
|
| 20 |
NORTHERN TRUST CORP |
14,486 |
262,000 |
0.12% |
|
|
| 21 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
14,200 |
257,000 |
0.11% |
|
|
| 22 |
Bank of New York Mellon Corp |
14,082 |
255,000 |
0.11% |
|
|
| 23 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
13,049 |
236,000 |
0.10% |
|
|
| 24 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
11,000 |
199,000 |
0.09% |
|
|
| 25 |
ClariVest Asset Management LLC |
8,700 |
157,000 |
0.07% |
|
|
| 26 |
TEACHERS ADVISORS, LLC |
5,574 |
101,000 |
0.04% |
|
|
| 27 |
TCI Wealth Advisors, Inc. |
4,900 |
89,000 |
0.04% |
|
|
| 28 |
DEUTSCHE BANK AG\ |
3,603 |
65,000 |
0.03% |
|
|
| 29 |
WELLS FARGO & COMPANY/MN |
2,650 |
48,000 |
0.02% |
|
|
| 30 |
BLACKROCK ADVISORS LLC |
2,482 |
45,000 |
0.02% |
|
|
| 31 |
STRS OHIO |
2,000 |
36,000 |
0.02% |
|
|
| 32 |
UBS AG |
1,780 |
32,000 |
0.01% |
|
|
| 33 |
Nationwide Fund Advisors |
1,740 |
31,000 |
0.01% |
|
|
| 34 |
BANK OF AMERICA CORP /DE/ |
1,248 |
23,000 |
0.01% |
|
|
| 35 |
Ground Swell Capital, LLC |
1,078 |
20,000 |
0.01% |
|
|
| 36 |
CITIGROUP INC |
865 |
16,000 |
0.01% |
|
|
| 37 |
Sensible Financial Planning & Management, LLC. |
610 |
11,000 |
0.00% |
|
|
| 38 |
Tower Research Capital LLC (TRC) |
438 |
8,000 |
0.00% |
|
|
| 39 |
BlackRock Japan Co. Ltd |
373 |
7,000 |
0.00% |
|
|
| 40 |
FIRST MANHATTAN CO. LLC. |
250 |
4,000 |
0.00% |
|
|
| 41 |
BARCLAYS PLC |
100 |
2,000 |
0.00% |
|
|
