| 1 |
GOLDMAN SACHS GROUP INC |
4,252,616 |
33,553,000 |
21.69% |
|
|
| 2 |
Aisling Capital LLC |
2,830,992 |
22,337,000 |
14.44% |
|
|
| 3 |
Polaris Venture Management Co. V, L.L.C. |
1,875,524 |
14,798,000 |
9.56% |
|
|
| 4 |
Senvest Management, LLC |
1,651,231 |
13,028,000 |
8.42% |
|
|
| 5 |
WELLINGTON MANAGEMENT GROUP LLP |
1,618,239 |
12,768,000 |
8.25% |
|
|
| 6 |
Lagoda Investment Management, L.P. |
1,420,628 |
11,209,000 |
7.24% |
|
|
| 7 |
TIGER MANAGEMENT L.L.C. |
1,245,138 |
9,824,000 |
6.35% |
|
|
| 8 |
Point72 Asset Management, L.P. |
1,017,833 |
8,031,000 |
5.19% |
|
|
| 9 |
FLAGSHIP VENTURES FUND IV GENERAL PARTNER LLC |
741,755 |
5,852,000 |
3.78% |
|
|
| 10 |
VANGUARD GROUP INC |
511,978 |
4,039,000 |
2.61% |
|
|
| 11 |
GILDER GAGNON HOWE & CO LLC |
412,150 |
3,252,000 |
2.10% |
|
|
| 12 |
BlackRock Fund Advisors |
377,575 |
2,979,000 |
1.93% |
|
|
| 13 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
334,253 |
2,637,000 |
1.70% |
|
|
| 14 |
BlackRock Institutional Trust Company, N.A. |
194,468 |
1,534,000 |
0.99% |
|
|
| 15 |
STATE STREET CORP |
181,925 |
1,437,000 |
0.93% |
|
|
| 16 |
NORTHERN TRUST CORP |
177,014 |
1,396,000 |
0.90% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
108,865 |
858,000 |
0.55% |
|
|
| 18 |
Spark Investment Management LLC |
100,300 |
791,000 |
0.51% |
|
|
| 19 |
BlackRock Investment Management, LLC |
54,728 |
432,000 |
0.28% |
|
|
| 20 |
Bank of New York Mellon Corp |
44,105 |
348,000 |
0.22% |
|
|
| 21 |
UBS Group AG |
43,584 |
344,000 |
0.22% |
|
|
| 22 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
39,289 |
310,000 |
0.20% |
|
|
| 23 |
WOODSTOCK CORP |
37,335 |
295,000 |
0.19% |
|
|
| 24 |
MORGAN STANLEY |
31,685 |
250,000 |
0.16% |
|
|
| 25 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
30,640 |
242,000 |
0.16% |
|
|
| 26 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
30,170 |
238,000 |
0.15% |
|
|
| 27 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
21,600 |
171,000 |
0.11% |
|
|
| 28 |
TEACHERS ADVISORS, LLC |
20,063 |
158,000 |
0.10% |
|
|
| 29 |
TFS CAPITAL LLC |
19,537 |
154,000 |
0.10% |
|
|
| 30 |
DEUTSCHE BANK AG\ |
15,153 |
118,000 |
0.08% |
|
|
| 31 |
Weiss Multi-Strategy Advisers LLC |
14,580 |
115,000 |
0.07% |
|
|
| 32 |
Virtu KCG Holdings LLC |
12,625 |
100,000 |
0.06% |
|
|
| 33 |
D. E. Shaw & Co., Inc. |
11,748 |
93,000 |
0.06% |
|
|
| 34 |
ROCKEFELLER FINANCIAL SERVICES INC |
11,766 |
93,000 |
0.06% |
|
|
| 35 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
11,218 |
89,000 |
0.06% |
|
|
| 36 |
CREDIT SUISSE AG/ |
11,229 |
88,000 |
0.06% |
|
|
| 37 |
RHUMBLINE ADVISERS |
10,605 |
84,000 |
0.05% |
|
|
| 38 |
WOLVERINE TRADING LP /BD |
100 |
83,900 |
0.05% |
Call |
|
| 39 |
Nationwide Fund Advisors |
9,037 |
71,000 |
0.05% |
|
|
| 40 |
AMERICAN INTERNATIONAL GROUP, INC. |
8,412 |
66,371 |
0.04% |
|
|
| 41 |
NEW YORK STATE COMMON RETIREMENT FUND |
8,300 |
65,000 |
0.04% |
|
|
| 42 |
NISA INVESTMENT ADVISORS, LLC |
8,000 |
63,000 |
0.04% |
|
|
| 43 |
BLACKROCK ADVISORS LLC |
6,783 |
54,000 |
0.03% |
|
|
| 44 |
TCI Wealth Advisors, Inc. |
4,900 |
39,000 |
0.03% |
|
|
| 45 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
4,128 |
33,000 |
0.02% |
|
|
| 46 |
WOLVERINE TRADING LP /BD |
3,932 |
32,989 |
0.02% |
|
|
| 47 |
PNC FINANCIAL SERVICES GROUP, INC. |
4,000 |
32,000 |
0.02% |
|
|
| 48 |
Tower Research Capital LLC (TRC) |
3,754 |
30,000 |
0.02% |
|
|
| 49 |
WELLS FARGO & COMPANY/MN |
3,063 |
24,000 |
0.02% |
|
|
| 50 |
JPMORGAN CHASE & CO |
2,519 |
20,000 |
0.01% |
|
|
