| 1 |
GOLDMAN SACHS GROUP INC |
3,474,899 |
30,441,000 |
24.79% |
|
|
| 2 |
Aisling Capital LLC |
2,523,300 |
22,104,000 |
18.00% |
|
|
| 3 |
Polaris Venture Management Co. V, L.L.C. |
2,018,450 |
17,682,000 |
14.40% |
|
|
| 4 |
GILDER GAGNON HOWE & CO LLC |
1,182,532 |
10,359,000 |
8.44% |
|
|
| 5 |
WELLINGTON MANAGEMENT GROUP LLP |
1,122,040 |
9,828,000 |
8.00% |
|
|
| 6 |
Senvest Management, LLC |
593,066 |
5,195,000 |
4.23% |
|
|
| 7 |
Point72 Asset Management, L.P. |
500,000 |
4,380,000 |
3.57% |
|
|
| 8 |
PRICE T ROWE ASSOCIATES INC /MD/ |
467,613 |
4,096,000 |
3.34% |
|
|
| 9 |
VANGUARD GROUP INC |
396,475 |
3,473,000 |
2.83% |
|
|
| 10 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
259,740 |
2,275,000 |
1.85% |
|
|
| 11 |
BlackRock Fund Advisors |
236,012 |
2,067,000 |
1.68% |
|
|
| 12 |
MILLENNIUM MANAGEMENT LLC |
186,675 |
1,635,000 |
1.33% |
|
|
| 13 |
SABBY MANAGEMENT, LLC |
154,521 |
1,354,000 |
1.10% |
|
|
| 14 |
AlpInvest Partners B.V. |
134,087 |
1,175,000 |
0.96% |
|
|
| 15 |
NORTHERN TRUST CORP |
113,009 |
990,000 |
0.81% |
|
|
| 16 |
BlackRock Institutional Trust Company, N.A. |
97,973 |
858,000 |
0.70% |
|
|
| 17 |
STATE STREET CORP |
61,311 |
539,000 |
0.44% |
|
|
| 18 |
TFS CAPITAL LLC |
60,581 |
531,000 |
0.43% |
|
|
| 19 |
MORGAN STANLEY |
46,990 |
412,000 |
0.34% |
|
|
| 20 |
GEODE CAPITAL MANAGEMENT, LLC |
39,847 |
349,000 |
0.28% |
|
|
| 21 |
WOODSTOCK CORP |
37,329 |
327,000 |
0.27% |
|
|
| 22 |
BlackRock Investment Management, LLC |
31,001 |
272,000 |
0.22% |
|
|
| 23 |
Bank of New York Mellon Corp |
30,525 |
267,000 |
0.22% |
|
|
| 24 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
29,130 |
255,000 |
0.21% |
|
|
| 25 |
Weiss Multi-Strategy Advisers LLC |
25,000 |
219,000 |
0.18% |
|
|
| 26 |
A.R.T. Advisors, LLC |
24,515 |
214,000 |
0.17% |
|
|
| 27 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
23,152 |
203,000 |
0.17% |
|
|
| 28 |
RENAISSANCE TECHNOLOGIES LLC |
17,500 |
153,000 |
0.12% |
|
|
| 29 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
16,500 |
145,000 |
0.12% |
|
|
| 30 |
D. E. Shaw & Co., Inc. |
16,403 |
144,000 |
0.12% |
|
|
| 31 |
DEUTSCHE BANK AG\ |
15,726 |
136,000 |
0.11% |
|
|
| 32 |
Spark Investment Management LLC |
15,000 |
130,000 |
0.11% |
|
|
| 33 |
TEACHERS ADVISORS, LLC |
13,325 |
117,000 |
0.10% |
|
|
| 34 |
NEW YORK STATE COMMON RETIREMENT FUND |
8,300 |
73,000 |
0.06% |
|
|
| 35 |
BLACKROCK ADVISORS LLC |
6,690 |
59,000 |
0.05% |
|
|
| 36 |
Nationwide Fund Advisors |
5,810 |
51,000 |
0.04% |
|
|
| 37 |
AMERICAN INTERNATIONAL GROUP, INC. |
5,332 |
47,000 |
0.04% |
|
|
| 38 |
TCI Wealth Advisors, Inc. |
4,900 |
43,000 |
0.04% |
|
|
| 39 |
Walleye Trading LLC |
4,600 |
40,000 |
0.03% |
|
|
| 40 |
PNC FINANCIAL SERVICES GROUP, INC. |
4,000 |
36,000 |
0.03% |
|
|
| 41 |
Tower Research Capital LLC (TRC) |
2,532 |
22,000 |
0.02% |
|
|
| 42 |
Cubist Systematic Strategies, LLC |
2,123 |
19,000 |
0.02% |
|
|
| 43 |
UBS Group AG |
2,000 |
18,000 |
0.01% |
|
|
| 44 |
BNP PARIBAS FINANCIAL MARKETS |
1,879 |
16,460 |
0.01% |
|
|
| 45 |
BANK OF AMERICA CORP /DE/ |
1,223 |
10,000 |
0.01% |
|
|
| 46 |
Sensible Financial Planning & Management, LLC. |
610 |
5,000 |
0.00% |
|
|
| 47 |
ROYAL BANK OF CANADA |
326 |
3,000 |
0.00% |
|
|
| 48 |
ATWOOD & PALMER INC |
294 |
3,000 |
0.00% |
|
|
| 49 |
FIRST MANHATTAN CO. LLC. |
250 |
2,000 |
0.00% |
|
|
| 50 |
BlackRock Finance, Inc. |
200 |
2,000 |
0.00% |
|
|
