| 1 |
BAKER BROS. ADVISORS LP |
1,821,967 |
16,853,000 |
24.58% |
|
|
| 2 |
JENNISON ASSOCIATES LLC |
1,088,495 |
10,069,000 |
14.68% |
|
|
| 3 |
DSC Advisors, L.P. |
871,653 |
8,063,000 |
11.76% |
|
|
| 4 |
Pentwater Capital Management LP |
680,000 |
6,290,000 |
9.17% |
|
|
| 5 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
679,627 |
6,287,000 |
9.17% |
|
|
| 6 |
SENZAR ASSET MANAGEMENT, LLC |
568,549 |
5,259,000 |
7.67% |
|
|
| 7 |
MENORA MIVTACHIM HOLDINGS LTD. |
407,121 |
3,766,000 |
5.49% |
|
|
| 8 |
DRIEHAUS CAPITAL MANAGEMENT LLC |
320,742 |
2,967,000 |
4.33% |
|
|
| 9 |
Alyeska Investment Group, L.P. |
201,070 |
1,860,000 |
2.71% |
|
|
| 10 |
SPHERA FUNDS MANAGEMENT LTD. |
200,000 |
1,850,000 |
2.70% |
|
|
| 11 |
ASCEND CAPITAL, LLC |
124,551 |
1,152,000 |
1.68% |
|
|
| 12 |
FRED ALGER MANAGEMENT, LLC |
68,500 |
634,000 |
0.92% |
|
|
| 13 |
MENTA CAPITAL LLC |
65,559 |
606,000 |
0.88% |
|
|
| 14 |
FEDERATED HERMES, INC. |
60,000 |
555,000 |
0.81% |
|
|
| 15 |
MILLENNIUM MANAGEMENT LLC |
56,900 |
526,000 |
0.77% |
|
|
| 16 |
ACADIAN ASSET MANAGEMENT LLC |
45,692 |
422,000 |
0.62% |
|
|
| 17 |
PANAGORA ASSET MANAGEMENT INC |
24,814 |
230,000 |
0.34% |
|
|
| 18 |
ARDSLEY ADVISORY PARTNERS LP |
20,000 |
185,000 |
0.27% |
|
|
| 19 |
BlackRock Fund Advisors |
19,259 |
178,000 |
0.26% |
|
|
| 20 |
Spark Investment Management LLC |
16,900 |
156,000 |
0.23% |
|
|
| 21 |
SABBY MANAGEMENT, LLC |
15,300 |
142,000 |
0.21% |
|
|
| 22 |
Robert W. Baird & Co. Inc |
15,000 |
139,000 |
0.20% |
|
|
| 23 |
MORGAN STANLEY |
14,919 |
139,000 |
0.20% |
|
|
| 24 |
A.R.T. Advisors, LLC |
13,331 |
123,000 |
0.18% |
|
|
| 25 |
WELLS FARGO & COMPANY/MN |
3,140 |
29,000 |
0.04% |
|
|
| 26 |
GUPTA WEALTH MANAGEMENT LLC |
3,000 |
28,000 |
0.04% |
|
|
| 27 |
UBS Group AG |
2,857 |
26,000 |
0.04% |
|
|
| 28 |
Stevens First Principles Investment Advisors |
2,000 |
19,000 |
0.03% |
|
|
| 29 |
BlackRock Investment Management, LLC |
1,099 |
10,000 |
0.01% |
|
|
| 30 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
500 |
5,000 |
0.01% |
|
|
