| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | AXA S.A. | 942,735 | 4,374,000 | 4.29% | ||
| 52 | PERCEPTIVE ADVISORS LLC | 1,117,324 | 5,184,000 | 5.08% | ||
| 53 | Opaleye Management Inc. | 1,135,000 | 5,266,000 | 5.16% | ||
| 54 | DSC Advisors, L.P. | 1,186,654 | 5,506,000 | 5.40% | ||
| 55 | FRANKLIN RESOURCES INC | 1,499,370 | 6,957,000 | 6.82% | ||
| 56 | BAKER BROS. ADVISORS LP | 2,466,702 | 11,445,000 | 11.22% | ||
| 57 | GREAT POINT PARTNERS LLC | 4,781,708 | 22,187,000 | 21.75% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.