| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 5,814,630 | 36,632,000 | 49.67% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 1,844,925 | 11,624,000 | 15.76% | ||
| 3 | Jefferies Group LLC | 1,136,763 | 7,162,000 | 9.71% | ||
| 4 | PERCEPTIVE ADVISORS LLC | 99,989 | 6,300,000 | 8.54% | ||
| 5 | Silver Rock Financial LLC | 450,000 | 2,835,000 | 3.84% | ||
| 6 | BAKER BROS. ADVISORS LP | 400,000 | 2,520,000 | 3.42% | ||
| 7 | PointState Capital LP | 300,000 | 1,887,000 | 2.56% | ||
| 8 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 175,000 | 1,103,000 | 1.50% | ||
| 9 | NORGES BANK | 175,000 | 1,102,000 | 1.49% | ||
| 10 | SPHERA FUNDS MANAGEMENT LTD. | 150,000 | 945,000 | 1.28% | ||
| 11 | DAFNA Capital Management LLC | 120,000 | 756,000 | 1.03% | SH | |
| 12 | Alyeska Investment Group, L.P. | 100,000 | 630,000 | 0.85% | ||
| 13 | JANE STREET GROUP, LLC | 19,370 | 122,000 | 0.17% | ||
| 14 | DEUTSCHE BANK AG\ | 17,858 | 112,000 | 0.15% | ||
| 15 | UBS AG | 2,577 | 16,000 | 0.02% | ||
| 16 | MORGAN STANLEY | 238 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
