| 1 |
FRANKLIN RESOURCES INC |
2,182,185 |
2,204,000 |
44.27% |
|
|
| 2 |
SPHERA FUNDS MANAGEMENT LTD. |
1,340,588 |
1,354,000 |
27.19% |
|
|
| 3 |
ORBIMED ADVISORS LLC |
567,600 |
573,000 |
11.51% |
|
|
| 4 |
VANGUARD GROUP INC |
186,821 |
188,000 |
3.78% |
|
|
| 5 |
BlackRock Institutional Trust Company, N.A. |
116,511 |
118,000 |
2.37% |
|
|
| 6 |
BlackRock Fund Advisors |
101,703 |
103,000 |
2.07% |
|
|
| 7 |
BOOTHBAY FUND MANAGEMENT, LLC |
78,662 |
79,000 |
1.59% |
|
|
| 8 |
PANAGORA ASSET MANAGEMENT INC |
55,973 |
57,000 |
1.14% |
|
|
| 9 |
GEODE CAPITAL MANAGEMENT, LLC |
55,834 |
56,000 |
1.12% |
|
|
| 10 |
Creative Planning |
51,000 |
52,000 |
1.04% |
|
|
| 11 |
Virtu KCG Holdings LLC |
49,847 |
50,000 |
1.00% |
|
|
| 12 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
30,000 |
30,000 |
0.60% |
|
|
| 13 |
NORTHERN TRUST CORP |
21,470 |
22,000 |
0.44% |
|
|
| 14 |
UBS Group AG |
19,623 |
20,000 |
0.40% |
|
|
| 15 |
A.R.T. Advisors, LLC |
16,830 |
16,000 |
0.32% |
|
|
| 16 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
14,323 |
14,000 |
0.28% |
|
|
| 17 |
Squarepoint Ops LLC |
13,000 |
13,000 |
0.26% |
|
|
| 18 |
MORGAN STANLEY |
10,848 |
11,000 |
0.22% |
|
|
| 19 |
SHANDA ASSET MANAGEMENT HOLDINGS Ltd |
10,000 |
10,000 |
0.20% |
|
|
| 20 |
CAPITAL GUARDIAN TRUST CO |
4,120 |
4,000 |
0.08% |
|
|
| 21 |
NEXT Financial Group, Inc |
2,670 |
3,000 |
0.06% |
|
|
| 22 |
BlackRock Investment Management, LLC |
2,024 |
2,000 |
0.04% |
|
|
| 23 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
161 |
0 |
0.00% |
|
|
