| 1 |
FRANKLIN RESOURCES INC |
2,182,185 |
3,972,000 |
36.03% |
|
|
| 2 |
SPHERA FUNDS MANAGEMENT LTD. |
1,340,588 |
2,440,000 |
22.13% |
|
|
| 3 |
ArrowMark Colorado Holdings LLC |
942,059 |
1,715,000 |
15.56% |
|
|
| 4 |
ORBIMED ADVISORS LLC |
567,600 |
1,033,000 |
9.37% |
|
|
| 5 |
VANGUARD GROUP INC |
365,699 |
665,000 |
6.03% |
|
|
| 6 |
Virtu KCG Holdings LLC |
90,063 |
164,000 |
1.49% |
|
|
| 7 |
BlackRock Fund Advisors |
86,253 |
157,000 |
1.42% |
|
|
| 8 |
Palo Alto Investors LP |
63,517 |
116,000 |
1.05% |
|
|
| 9 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
57,767 |
105,000 |
0.95% |
|
|
| 10 |
PANAGORA ASSET MANAGEMENT INC |
55,973 |
102,000 |
0.93% |
|
|
| 11 |
GEODE CAPITAL MANAGEMENT, LLC |
55,658 |
101,000 |
0.92% |
|
|
| 12 |
BOOTHBAY FUND MANAGEMENT, LLC |
52,432 |
95,000 |
0.86% |
|
|
| 13 |
A.R.T. Advisors, LLC |
39,100 |
71,000 |
0.64% |
|
|
| 14 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
30,000 |
55,000 |
0.50% |
|
|
| 15 |
Creative Planning |
25,500 |
46,000 |
0.42% |
|
|
| 16 |
UBS Group AG |
23,925 |
44,000 |
0.40% |
|
|
| 17 |
BlackRock Institutional Trust Company, N.A. |
22,956 |
42,000 |
0.38% |
|
|
| 18 |
NORTHERN TRUST CORP |
21,108 |
38,000 |
0.34% |
|
|
| 19 |
TWO SIGMA SECURITIES, LLC |
15,697 |
29,000 |
0.26% |
|
|
| 20 |
SHANDA ASSET MANAGEMENT HOLDINGS Ltd |
10,000 |
18,000 |
0.16% |
|
|
| 21 |
CAPITAL GUARDIAN TRUST CO |
4,120 |
7,000 |
0.06% |
|
|
| 22 |
BlackRock Investment Management, LLC |
2,024 |
4,000 |
0.04% |
|
|
| 23 |
MORGAN STANLEY |
1,100 |
2,000 |
0.02% |
|
|
| 24 |
NEXT Financial Group, Inc |
1,040 |
2,000 |
0.02% |
|
|
| 25 |
BANK OF AMERICA CORP /DE/ |
550 |
1,000 |
0.01% |
|
|
| 26 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
161 |
0 |
0.00% |
|
|
