| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 3,411,500 | 57,518,000 | 18.66% | ||
| 2 | WESTFIELD CAPITAL MANAGEMENT CO LP | 1,696,760 | 28,607,000 | 9.28% | ||
| 3 | PUTNAM INVESTMENTS LLC | 1,428,092 | 24,077,000 | 7.81% | ||
| 4 | Polar Capital LLP | 1,175,392 | 19,817,000 | 6.43% | ||
| 5 | STATE STREET CORP | 1,070,062 | 18,041,000 | 5.85% | ||
| 6 | CLOUGH CAPITAL PARTNERS L P | 967,808 | 16,317,000 | 5.29% | ||
| 7 | VANGUARD GROUP INC | 955,956 | 16,117,000 | 5.23% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 862,412 | 14,540,000 | 4.72% | ||
| 9 | Broadfin Capital, LLC | 766,010 | 12,915,000 | 4.19% | ||
| 10 | FRANKLIN RESOURCES INC | 734,730 | 12,388,000 | 4.02% | ||
| 11 | BlackRock Fund Advisors | 723,932 | 12,205,000 | 3.96% | ||
| 12 | AMERIPRISE FINANCIAL INC | 517,925 | 8,733,000 | 2.83% | ||
| 13 | NORTHERN TRUST CORP | 276,717 | 4,665,000 | 1.51% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 265,714 | 4,480,000 | 1.45% | ||
| 15 | D. E. Shaw & Co., Inc. | 252,835 | 4,263,000 | 1.38% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 211,100 | 3,559,000 | 1.15% | Call | |
| 17 | Avoro Capital Advisors LLC | 199,332 | 3,361,000 | 1.09% | ||
| 18 | OXFORD ASSET MANAGEMENT LLP | 176,240 | 2,997,000 | 0.97% | ||
| 19 | FMR LLC | 168,000 | 2,832,000 | 0.92% | ||
| 20 | MORGAN STANLEY | 159,052 | 2,682,000 | 0.87% | ||
| 21 | BLAIR WILLIAM & CO/IL | 151,206 | 2,549,000 | 0.83% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 147,954 | 2,494,000 | 0.81% | ||
| 23 | Bank of New York Mellon Corp | 143,473 | 2,419,000 | 0.78% | ||
| 24 | CITADEL ADVISORS LLC | 135,693 | 2,287,000 | 0.74% | ||
| 25 | PANAGORA ASSET MANAGEMENT INC | 124,204 | 2,094,000 | 0.68% | ||
| 26 | KENNEDY CAPITAL MANAGEMENT LLC | 114,949 | 1,938,000 | 0.63% | ||
| 27 | TIAA CREF INVESTMENT MANAGEMENT LLC | 113,754 | 1,918,000 | 0.62% | ||
| 28 | New Leaf Venture Partners, L.L.C. | 112,700 | 1,900,000 | 0.62% | ||
| 29 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 104,436 | 1,761,000 | 0.57% | ||
| 30 | BlackRock Investment Management, LLC | 87,011 | 1,467,000 | 0.48% | ||
| 31 | DEUTSCHE BANK AG\ | 84,103 | 1,416,000 | 0.46% | ||
| 32 | WELLINGTON MANAGEMENT GROUP LLP | 76,300 | 1,286,000 | 0.42% | ||
| 33 | Numeric Investors LLC | 50,571 | 853,000 | 0.28% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 49,050 | 827,000 | 0.27% | ||
| 35 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 48,731 | 822,000 | 0.27% | ||
| 36 | CREDIT SUISSE AG/ | 45,115 | 761,000 | 0.25% | ||
| 37 | HOWARD HUGHES MEDICAL INSTITUTE | 43,355 | 731,000 | 0.24% | ||
| 38 | ALLIANCEBERNSTEIN L.P. | 42,530 | 717,000 | 0.23% | ||
| 39 | UBS Group AG | 40,000 | 674,000 | 0.22% | Put | |
| 40 | TURNER INVESTMENTS LLC | 38,104 | 642,000 | 0.21% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 36,600 | 617,000 | 0.20% | Put | |
| 42 | TEACHERS ADVISORS, LLC | 35,902 | 605,000 | 0.20% | ||
| 43 | C WorldWide Group Holding A/S | 34,962 | 589,000 | 0.19% | ||
| 44 | RHUMBLINE ADVISERS | 33,622 | 567,000 | 0.18% | ||
| 45 | Nine Chapters Capital Management LLC | 29,700 | 501,000 | 0.16% | ||
| 46 | Swiss National Bank | 27,140 | 458,000 | 0.15% | ||
| 47 | AlphaOne Investment Services, LLC | 24,425 | 412,000 | 0.13% | ||
| 48 | MACKENZIE FINANCIAL CORP | 21,800 | 368,000 | 0.12% | ||
| 49 | METROPOLITAN LIFE INSURANCE CO/NY | 21,540 | 363,000 | 0.12% | ||
| 50 | C Partners Holding GmbH | 20,697 | 349,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
