| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 3,619,173 | 14,296,000 | 12.73% | ||
| 2 | Senvest Management, LLC | 1,631,003 | 6,442,000 | 5.74% | ||
| 3 | VANGUARD GROUP INC | 1,595,289 | 6,302,000 | 5.61% | ||
| 4 | BLAIR WILLIAM & CO/IL | 1,322,793 | 5,225,000 | 4.65% | ||
| 5 | FMR LLC | 1,263,235 | 4,990,000 | 4.44% | ||
| 6 | BlackRock Fund Advisors | 1,246,397 | 4,923,000 | 4.38% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 1,163,514 | 4,596,000 | 4.09% | ||
| 8 | Redmile Group, LLC | 1,049,791 | 4,147,000 | 3.69% | ||
| 9 | FRANKLIN RESOURCES INC | 978,730 | 3,866,000 | 3.44% | ||
| 10 | AMERIPRISE FINANCIAL INC | 976,468 | 3,858,000 | 3.44% | ||
| 11 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 801,615 | 3,166,000 | 2.82% | ||
| 12 | GMT CAPITAL CORP | 707,200 | 2,793,000 | 2.49% | ||
| 13 | STATE STREET CORP | 705,640 | 2,786,000 | 2.48% | ||
| 14 | PICTET ASSET MANAGEMENT LTD | 653,394 | 2,581,000 | 2.30% | ||
| 15 | KORNITZER CAPITAL MANAGEMENT INC /KS | 577,200 | 2,280,000 | 2.03% | ||
| 16 | NORTHERN TRUST CORP | 492,100 | 1,944,000 | 1.73% | ||
| 17 | PANAGORA ASSET MANAGEMENT INC | 487,898 | 1,927,000 | 1.72% | ||
| 18 | Rhenman & Partners Asset Management AB | 485,000 | 1,916,000 | 1.71% | ||
| 19 | RENAISSANCE TECHNOLOGIES LLC | 463,951 | 1,833,000 | 1.63% | ||
| 20 | GLENHILL ADVISORS LLC | 415,893 | 1,643,000 | 1.46% | ||
| 21 | GOLDMAN SACHS GROUP INC | 400,491 | 1,582,000 | 1.41% | ||
| 22 | VIVO CAPITAL, LLC | 359,828 | 1,421,000 | 1.27% | ||
| 23 | Tekla Capital Management LLC | 345,050 | 1,363,000 | 1.21% | ||
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 299,700 | 1,184,000 | 1.05% | Put | |
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 272,946 | 1,078,000 | 0.96% | ||
| 26 | C WorldWide Group Holding A/S | 262,769 | 1,038,000 | 0.92% | ||
| 27 | DEUTSCHE BANK AG\ | 261,818 | 1,033,000 | 0.92% | ||
| 28 | New Leaf Venture Partners, L.L.C. | 256,381 | 1,013,000 | 0.90% | ||
| 29 | MILLENNIUM MANAGEMENT LLC | 231,928 | 916,000 | 0.82% | ||
| 30 | NORDEA INVESTMENT MANAGEMENT AB | 216,917 | 857,000 | 0.76% | ||
| 31 | AXA S.A. | 211,200 | 834,000 | 0.74% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 201,800 | 797,000 | 0.71% | Call | |
| 33 | PAULSON & CO. INC. | 174,000 | 687,000 | 0.61% | ||
| 34 | Bank of New York Mellon Corp | 170,373 | 673,000 | 0.60% | ||
| 35 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 166,878 | 659,000 | 0.59% | ||
| 36 | Rock Springs Capital Management LP | 165,000 | 652,000 | 0.58% | ||
| 37 | MORGAN STANLEY | 156,976 | 620,000 | 0.55% | ||
| 38 | BlackRock Investment Management, LLC | 153,252 | 605,000 | 0.54% | ||
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 152,896 | 604,000 | 0.54% | ||
| 40 | JPMORGAN CHASE & CO | 138,015 | 546,000 | 0.49% | ||
| 41 | Squarepoint Ops LLC | 127,899 | 505,000 | 0.45% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 124,460 | 492,000 | 0.44% | ||
| 43 | CITADEL ADVISORS LLC | 113,700 | 449,000 | 0.40% | Put | |
| 44 | ROYCE & ASSOCIATES LP | 111,000 | 438,000 | 0.39% | ||
| 45 | Jefferies Group LLC | 103,800 | 410,000 | 0.37% | Call | |
| 46 | Amici Capital, LLC | 100,000 | 395,000 | 0.35% | ||
| 47 | WOLVERINE TRADING LP /BD | 82,600 | 326,000 | 0.29% | Put | |
| 48 | RUSSELL INVESTMENTS GROUP, LTD. | 77,324 | 317,000 | 0.28% | ||
| 49 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 80,005 | 316,000 | 0.28% | ||
| 50 | FT OPTIONS LLC | 28,000 | 297,000 | 0.26% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
