| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | 3,880,466 | 82,615,000 | 11.53% | ||
| 2 | Visium Asset Management, LP | 2,363,759 | 50,325,000 | 7.02% | ||
| 3 | WADDELL & REED FINANCIAL INC | 2,031,512 | 43,250,000 | 6.03% | ||
| 4 | BlackRock Fund Advisors | 1,956,290 | 41,649,000 | 5.81% | ||
| 5 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,760,000 | 37,470,000 | 5.23% | ||
| 6 | JANUS HENDERSON INVESTORS US LLC | 1,745,175 | 37,156,000 | 5.18% | ||
| 7 | STATE STREET CORP | 1,330,809 | 28,335,000 | 3.95% | ||
| 8 | JPMORGAN CHASE & CO | 1,279,322 | 27,236,000 | 3.80% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,217,068 | 25,911,000 | 3.62% | ||
| 10 | FMR LLC | 1,024,903 | 21,820,000 | 3.04% | ||
| 11 | PRICE T ROWE ASSOCIATES INC /MD/ | 926,327 | 19,722,000 | 2.75% | ||
| 12 | EcoR1 Capital, LLC | 863,745 | 18,389,000 | 2.57% | ||
| 13 | Omega Fund Management, LLC | 822,175 | 17,504,000 | 2.44% | ||
| 14 | GOLDMAN SACHS GROUP INC | 782,182 | 16,653,000 | 2.32% | ||
| 15 | USCA RIA LLC | 283,860 | 13,333,000 | 1.86% | ||
| 16 | GFS Advisors, LLC | 283,860 | 13,333,000 | 1.86% | ||
| 17 | FRANKLIN RESOURCES INC | 576,608 | 12,276,000 | 1.71% | ||
| 18 | NORTHERN TRUST CORP | 540,012 | 11,496,000 | 1.60% | ||
| 19 | BANK OF AMERICA CORP /DE/ | 513,364 | 10,929,000 | 1.53% | ||
| 20 | CREDIT SUISSE AG/ | 415,557 | 8,847,000 | 1.23% | ||
| 21 | TEACHERS ADVISORS, LLC | 383,198 | 8,158,000 | 1.14% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 375,845 | 8,001,000 | 1.12% | ||
| 23 | OppenheimerFunds, Inc. | 353,200 | 7,520,000 | 1.05% | ||
| 24 | PointState Capital LP | 350,000 | 7,452,000 | 1.04% | ||
| 25 | Opaleye Management Inc. | 325,000 | 6,919,000 | 0.97% | ||
| 26 | NORGES BANK | 322,326 | 6,862,000 | 0.96% | ||
| 27 | VERTEX ONE ASSET MANAGEMENT INC. | 310,000 | 6,600,000 | 0.92% | ||
| 28 | Candriam S.C.A. | 289,000 | 6,120,000 | 0.85% | ||
| 29 | Bank of New York Mellon Corp | 248,669 | 5,294,000 | 0.74% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 237,645 | 5,059,000 | 0.71% | ||
| 31 | Invesco Ltd. | 208,124 | 4,430,000 | 0.62% | ||
| 32 | Rock Springs Capital Management LP | 204,000 | 4,343,000 | 0.61% | ||
| 33 | Asset Management One Co., Ltd. | 179,704 | 3,705,000 | 0.52% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 172,546 | 3,674,000 | 0.51% | ||
| 35 | BlackRock Investment Management, LLC | 167,096 | 3,557,000 | 0.50% | ||
| 36 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 158,516 | 3,374,000 | 0.47% | ||
| 37 | ROYAL BANK OF CANADA | 157,573 | 3,355,000 | 0.47% | ||
| 38 | CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. | 156,956 | 3,341,000 | 0.47% | ||
| 39 | DEUTSCHE BANK AG\ | 129,009 | 2,745,000 | 0.38% | ||
| 40 | Informed Momentum Co LLC | 121,509 | 2,587,000 | 0.36% | ||
| 41 | JACOBS LEVY EQUITY MANAGEMENT, INC | 116,910 | 2,489,000 | 0.35% | ||
| 42 | OXFORD ASSET MANAGEMENT LLP | 115,152 | 2,452,000 | 0.34% | ||
| 43 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 115,072 | 2,450,000 | 0.34% | ||
| 44 | Rhenman & Partners Asset Management AB | 114,000 | 2,427,000 | 0.34% | ||
| 45 | D. E. Shaw & Co., Inc. | 111,267 | 2,369,000 | 0.33% | ||
| 46 | SABBY MANAGEMENT, LLC | 109,100 | 2,323,000 | 0.32% | ||
| 47 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 106,200 | 2,261,000 | 0.32% | Call | |
| 48 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 105,100 | 2,238,000 | 0.31% | ||
| 49 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 101,650 | 2,164,000 | 0.30% | ||
| 50 | PRINCIPAL FINANCIAL GROUP INC | 99,642 | 2,121,000 | 0.30% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
