| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 1,519,229 | 41,201,000 | 23.68% | ||
| 2 | JANUS HENDERSON INVESTORS US LLC | 912,022 | 24,734,000 | 14.22% | ||
| 3 | Invesco Ltd. | 770,629 | 20,900,000 | 12.01% | ||
| 4 | ALLIANCEBERNSTEIN L.P. | 613,961 | 16,651,000 | 9.57% | ||
| 5 | FRED ALGER MANAGEMENT, LLC | 485,302 | 13,161,000 | 7.56% | ||
| 6 | DEERFIELD MANAGEMENT COMPANY, L.P. | 482,300 | 13,080,000 | 7.52% | ||
| 7 | Visium Asset Management, LP | 468,165 | 12,697,000 | 7.30% | ||
| 8 | JENNISON ASSOCIATES LLC | 372,565 | 10,104,000 | 5.81% | ||
| 9 | Point72 Asset Management, L.P. | 181,410 | 4,920,000 | 2.83% | ||
| 10 | MILLENNIUM MANAGEMENT LLC | 167,933 | 4,554,000 | 2.62% | ||
| 11 | Asset Management One Co., Ltd. | 156,876 | 4,171,000 | 2.40% | ||
| 12 | PERCEPTIVE ADVISORS LLC | 112,622 | 3,054,000 | 1.76% | ||
| 13 | Ghost Tree Capital, LLC | 80,000 | 2,170,000 | 1.25% | ||
| 14 | WELLS FARGO & COMPANY/MN | 31,442 | 852,000 | 0.49% | ||
| 15 | BLUE ARROW CAPITAL MANAGEMENT LLC | 25,000 | 678,000 | 0.39% | ||
| 16 | CATAPULT CAPITAL MANAGEMENT LLC | 20,000 | 542,000 | 0.31% | ||
| 17 | MANAGED ACCOUNT ADVISORS LLC | 12,636 | 343,000 | 0.20% | ||
| 18 | MORGAN STANLEY | 5,587 | 152,000 | 0.09% | ||
| 19 | CITIGROUP INC | 1,200 | 33,000 | 0.02% | ||
| 20 | Stratos Wealth Partners, LTD. | 37 | 1,003 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
