| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 1,416,666 | 7,259,000 | 44.47% | ||
| 2 | Cormorant Asset Management, LP | 1,081,867 | 5,542,000 | 33.95% | ||
| 3 | SPHERA FUNDS MANAGEMENT LTD. | 221,096 | 1,415,000 | 8.67% | ||
| 4 | BVF INC/IL | 105,429 | 538,000 | 3.30% | ||
| 5 | BANK OF MONTREAL /CAN/ | 91,363 | 466,000 | 2.85% | ||
| 6 | DAFNA Capital Management LLC | 70,396 | 359,000 | 2.20% | ||
| 7 | BAKER BROS. ADVISORS LP | 33,397 | 170,000 | 1.04% | ||
| 8 | Weiss Multi-Strategy Advisers LLC | 25,000 | 128,000 | 0.78% | ||
| 9 | Trellus Management Company, LLC | 21,400 | 109,000 | 0.67% | ||
| 10 | Knoll Capital Management, LLC | 20,000 | 102,000 | 0.62% | ||
| 11 | ROYAL BANK OF CANADA | 17,107 | 87,000 | 0.53% | ||
| 12 | Spark Investment Management LLC | 12,000 | 61,000 | 0.37% | ||
| 13 | Tower Research Capital LLC (TRC) | 11,502 | 59,000 | 0.36% | ||
| 14 | DEUTSCHE BANK AG\ | 4,787 | 24,000 | 0.15% | ||
| 15 | MORGAN STANLEY | 621 | 3,000 | 0.02% | ||
| 16 | 1832 Asset Management L.P. | 100 | 1,000 | 0.01% | ||
| 17 | TORONTO DOMINION BANK | 76 | 0 | 0.00% | ||
| 18 | CITIGROUP INC | 2 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
