| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | WASATCH ADVISORS LP | 6,981,681 | 32,325,000 | 15.66% | ||
| 2 | BAKER BROS. ADVISORS LP | 4,055,876 | 18,779,000 | 9.10% | ||
| 3 | BlackRock Fund Advisors | 2,868,032 | 13,279,000 | 6.43% | ||
| 4 | VANGUARD GROUP INC | 2,725,744 | 12,620,000 | 6.11% | ||
| 5 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,500,000 | 11,575,000 | 5.61% | ||
| 6 | STATE STREET CORP | 2,426,552 | 11,231,000 | 5.44% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 1,847,789 | 8,555,000 | 4.14% | ||
| 8 | FMR LLC | 1,703,783 | 7,889,000 | 3.82% | ||
| 9 | Cormorant Asset Management, LP | 1,402,331 | 6,493,000 | 3.15% | ||
| 10 | VOYA INVESTMENT MANAGEMENT LLC | 1,355,208 | 6,275,000 | 3.04% | ||
| 11 | Numeric Investors LLC | 1,003,313 | 4,645,000 | 2.25% | ||
| 12 | RA CAPITAL MANAGEMENT, L.P. | 899,438 | 4,164,000 | 2.02% | ||
| 13 | NORTHERN TRUST CORP | 884,870 | 4,097,000 | 1.98% | ||
| 14 | FIC CAPITAL INC | 859,839 | 3,981,000 | 1.93% | ||
| 15 | ORBIMED ADVISORS LLC | 831,500 | 3,850,000 | 1.87% | ||
| 16 | DEUTSCHE BANK AG\ | 796,825 | 3,687,000 | 1.79% | ||
| 17 | ALTRINSIC GLOBAL ADVISORS LLC | 630,000 | 2,917,000 | 1.41% | ||
| 18 | MILLENNIUM MANAGEMENT LLC | 615,734 | 2,851,000 | 1.38% | ||
| 19 | RENAISSANCE TECHNOLOGIES LLC | 594,500 | 2,753,000 | 1.33% | ||
| 20 | ROYCE & ASSOCIATES LP | 536,100 | 2,482,000 | 1.20% | ||
| 21 | COLUMBUS CIRCLE INVESTORS | 516,497 | 2,391,000 | 1.16% | ||
| 22 | FRONTIER CAPITAL MANAGEMENT CO LLC | 514,076 | 2,380,000 | 1.15% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 512,638 | 2,373,000 | 1.15% | ||
| 24 | CREDIT SUISSE AG/ | 399,013 | 1,848,000 | 0.90% | ||
| 25 | MORGAN STANLEY | 332,634 | 1,540,000 | 0.75% | ||
| 26 | Bank of New York Mellon Corp | 314,241 | 1,455,000 | 0.70% | ||
| 27 | TIAA CREF INVESTMENT MANAGEMENT LLC | 299,321 | 1,386,000 | 0.67% | ||
| 28 | WELLS FARGO & COMPANY/MN | 292,636 | 1,354,000 | 0.66% | ||
| 29 | BlackRock Investment Management, LLC | 275,389 | 1,275,000 | 0.62% | ||
| 30 | I.G. INVESTMENT MANAGEMENT, LTD. | 240,000 | 1,111,000 | 0.54% | ||
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 239,085 | 1,107,000 | 0.54% | ||
| 32 | BLACKROCK ADVISORS LLC | 215,072 | 996,000 | 0.48% | ||
| 33 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 207,365 | 960,000 | 0.47% | ||
| 34 | Candriam S.C.A. | 200,000 | 926,000 | 0.45% | ||
| 35 | Piermont Capital Management Inc. | 169,079 | 783,000 | 0.38% | ||
| 36 | TEACHERS ADVISORS, LLC | 157,035 | 727,000 | 0.35% | ||
| 37 | D. E. Shaw & Co., Inc. | 151,321 | 701,000 | 0.34% | ||
| 38 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 146,581 | 679,000 | 0.33% | ||
| 39 | Parallax Volatility Advisers, L.P. | 145,800 | 675,000 | 0.33% | Call | |
| 40 | QS Investors, LLC | 145,236 | 672,000 | 0.33% | ||
| 41 | PRICE T ROWE ASSOCIATES INC /MD/ | 143,200 | 663,000 | 0.32% | ||
| 42 | GROUP ONE TRADING LLC | 141,087 | 653,000 | 0.32% | ||
| 43 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 134,622 | 623,000 | 0.30% | ||
| 44 | PDT Partners, LLC | 132,400 | 613,000 | 0.30% | ||
| 45 | Granite Investment Partners, LLC | 131,634 | 609,000 | 0.30% | ||
| 46 | GOLDMAN SACHS GROUP INC | 125,636 | 582,000 | 0.28% | ||
| 47 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 119,300 | 552,000 | 0.27% | ||
| 48 | DIMENSIONAL FUND ADVISORS LP | 117,374 | 543,000 | 0.26% | ||
| 49 | Swiss National Bank | 113,560 | 526,000 | 0.25% | ||
| 50 | PRINCETON CAPITAL MANAGEMENT INC | 107,145 | 496,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
