| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,499,326 | 230,051,000 | 18.32% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,658,187 | 135,913,000 | 10.82% | ||
| 3 | FEDERATED HERMES, INC. | 1,647,600 | 84,242,000 | 6.71% | ||
| 4 | VANGUARD GROUP INC | 1,512,600 | 77,340,000 | 6.16% | ||
| 5 | JPMORGAN CHASE & CO | 1,349,580 | 69,003,000 | 5.49% | ||
| 6 | BAKER BROS. ADVISORS LP | 1,318,341 | 67,407,000 | 5.37% | ||
| 7 | LORD, ABBETT & CO. LLC | 1,165,207 | 59,577,000 | 4.74% | ||
| 8 | BlackRock Fund Advisors | 759,506 | 38,834,000 | 3.09% | ||
| 9 | Clearbridge Investments, LLC | 641,962 | 32,824,000 | 2.61% | ||
| 10 | Rock Springs Capital Management LP | 610,000 | 31,189,000 | 2.48% | ||
| 11 | STATE STREET CORP | 476,796 | 24,375,000 | 1.94% | ||
| 12 | RS INVESTMENT MANAGEMENT CO LLC | 439,094 | 22,451,000 | 1.79% | ||
| 13 | Bain Capital Public Equity Management, LLC | 424,114 | 21,685,000 | 1.73% | ||
| 14 | Capital World Investors | 403,020 | 20,606,000 | 1.64% | ||
| 15 | JANUS HENDERSON INVESTORS US LLC | 401,990 | 20,553,000 | 1.64% | ||
| 16 | AMERICAN CENTURY COMPANIES INC | 394,995 | 20,196,000 | 1.61% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 393,601 | 20,125,000 | 1.60% | ||
| 18 | WELLINGTON MANAGEMENT GROUP LLP | 392,994 | 20,095,000 | 1.60% | ||
| 19 | DEERFIELD MANAGEMENT COMPANY, L.P. | 368,000 | 18,816,000 | 1.50% | ||
| 20 | GOLDMAN SACHS GROUP INC | 338,452 | 17,305,000 | 1.38% | ||
| 21 | MILLENNIUM MANAGEMENT LLC | 310,809 | 15,892,000 | 1.27% | ||
| 22 | VOYA INVESTMENT MANAGEMENT LLC | 277,212 | 14,174,000 | 1.13% | ||
| 23 | Invesco Ltd. | 244,085 | 12,480,000 | 0.99% | ||
| 24 | NORTHERN TRUST CORP | 201,958 | 10,326,000 | 0.82% | ||
| 25 | BARCLAYS PLC | 165,000 | 8,437,000 | 0.67% | Call | |
| 26 | CASDIN CAPITAL, LLC | 162,500 | 8,309,000 | 0.66% | ||
| 27 | GEODE CAPITAL MANAGEMENT, LLC | 150,574 | 7,698,000 | 0.61% | ||
| 28 | EVENTIDE ASSET MANAGEMENT, LLC | 150,000 | 7,670,000 | 0.61% | ||
| 29 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 147,511 | 7,542,000 | 0.60% | ||
| 30 | AXA S.A. | 140,278 | 7,172,000 | 0.57% | ||
| 31 | CQS Cayman LP | 134,669 | 6,886,000 | 0.55% | ||
| 32 | NORGES BANK | 122,590 | 6,268,000 | 0.50% | ||
| 33 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 112,402 | 5,747,000 | 0.46% | ||
| 34 | CITIGROUP INC | 100,000 | 5,113,000 | 0.41% | Call | |
| 35 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 97,654 | 4,993,000 | 0.40% | ||
| 36 | AMERIPRISE FINANCIAL INC | 97,604 | 4,991,000 | 0.40% | ||
| 37 | BALYASNY ASSET MANAGEMENT L.P. | 97,500 | 4,985,000 | 0.40% | ||
| 38 | Bank of New York Mellon Corp | 83,223 | 4,255,000 | 0.34% | ||
| 39 | TD ASSET MANAGEMENT INC | 68,851 | 3,520,000 | 0.28% | ||
| 40 | Laurion Capital Management LP | 68,000 | 3,477,000 | 0.28% | ||
| 41 | C WorldWide Group Holding A/S | 67,400 | 3,446,000 | 0.27% | ||
| 42 | BlackRock Investment Management, LLC | 63,750 | 3,260,000 | 0.26% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 62,288 | 3,185,000 | 0.25% | ||
| 44 | Iguana Healthcare Management, LLC | 60,000 | 3,068,000 | 0.24% | ||
| 45 | ALLIANCEBERNSTEIN L.P. | 56,900 | 2,909,000 | 0.23% | ||
| 46 | Candriam S.C.A. | 54,000 | 2,761,000 | 0.22% | ||
| 47 | TIAA CREF INVESTMENT MANAGEMENT LLC | 52,214 | 2,670,000 | 0.21% | ||
| 48 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 50,650 | 2,590,000 | 0.21% | ||
| 49 | Artal Group S.A. | 50,000 | 2,557,000 | 0.20% | ||
| 50 | EMERALD MUTUAL FUND ADVISERS TRUST | 49,916 | 2,552,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
