| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,593,173 | 275,866,000 | 17.80% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,906,496 | 174,564,000 | 11.27% | ||
| 3 | VANGUARD GROUP INC | 1,684,375 | 101,164,000 | 6.53% | ||
| 4 | FEDERATED HERMES, INC. | 1,633,900 | 98,132,000 | 6.33% | ||
| 5 | JPMORGAN CHASE & CO | 1,336,491 | 80,269,000 | 5.18% | ||
| 6 | BAKER BROS. ADVISORS LP | 1,318,341 | 79,180,000 | 5.11% | ||
| 7 | LORD, ABBETT & CO. LLC | 1,083,517 | 65,076,000 | 4.20% | ||
| 8 | BlackRock Fund Advisors | 894,515 | 53,725,000 | 3.47% | ||
| 9 | STATE STREET CORP | 802,814 | 48,213,000 | 3.11% | ||
| 10 | Clearbridge Investments, LLC | 641,378 | 38,521,000 | 2.49% | ||
| 11 | Rock Springs Capital Management LP | 625,000 | 37,538,000 | 2.42% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 519,585 | 31,206,000 | 2.01% | ||
| 13 | WELLINGTON MANAGEMENT GROUP LLP | 516,122 | 30,998,000 | 2.00% | ||
| 14 | GOLDMAN SACHS GROUP INC | 478,947 | 28,765,000 | 1.86% | ||
| 15 | VICTORY CAPITAL MANAGEMENT INC | 471,042 | 28,290,000 | 1.83% | ||
| 16 | AMERICAN CENTURY COMPANIES INC | 417,204 | 25,057,000 | 1.62% | ||
| 17 | Capital World Investors | 403,020 | 24,205,000 | 1.56% | ||
| 18 | JANUS HENDERSON INVESTORS US LLC | 395,024 | 23,725,000 | 1.53% | ||
| 19 | DEERFIELD MANAGEMENT COMPANY, L.P. | 368,000 | 22,102,000 | 1.43% | ||
| 20 | Bain Capital Public Equity Management, LLC | 367,314 | 22,061,000 | 1.42% | ||
| 21 | Invesco Ltd. | 282,422 | 16,962,000 | 1.09% | ||
| 22 | VOYA INVESTMENT MANAGEMENT LLC | 262,962 | 15,793,000 | 1.02% | ||
| 23 | NORTHERN TRUST CORP | 226,280 | 13,591,000 | 0.88% | ||
| 24 | BALYASNY ASSET MANAGEMENT L.P. | 195,900 | 11,766,000 | 0.76% | ||
| 25 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 174,420 | 10,476,000 | 0.68% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 162,987 | 9,788,000 | 0.63% | ||
| 27 | NORGES BANK | 164,960 | 9,463,000 | 0.61% | ||
| 28 | EVENTIDE ASSET MANAGEMENT, LLC | 150,000 | 9,009,000 | 0.58% | ||
| 29 | AXA S.A. | 140,359 | 8,430,000 | 0.54% | ||
| 30 | WELLS FARGO & COMPANY/MN | 134,331 | 8,068,000 | 0.52% | ||
| 31 | AMERIPRISE FINANCIAL INC | 129,627 | 7,786,000 | 0.50% | ||
| 32 | PointState Capital LP | 125,000 | 7,508,000 | 0.48% | ||
| 33 | PICTET ASSET MANAGEMENT LTD | 120,058 | 7,211,000 | 0.47% | ||
| 34 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 114,353 | 6,868,000 | 0.44% | ||
| 35 | BLACKROCK ADVISORS LLC | 100,695 | 6,048,000 | 0.39% | ||
| 36 | Bank of New York Mellon Corp | 94,284 | 5,662,000 | 0.37% | ||
| 37 | CASDIN CAPITAL, LLC | 93,500 | 5,616,000 | 0.36% | ||
| 38 | BlackRock Investment Management, LLC | 76,023 | 4,566,000 | 0.29% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 75,930 | 4,561,000 | 0.29% | ||
| 40 | EcoR1 Capital, LLC | 68,600 | 4,120,000 | 0.27% | ||
| 41 | GOLDMAN SACHS GROUP INC | 67,600 | 4,060,000 | 0.26% | Call | |
| 42 | DEUTSCHE BANK AG\ | 66,852 | 4,012,000 | 0.26% | ||
| 43 | TD ASSET MANAGEMENT INC | 65,851 | 3,955,000 | 0.26% | ||
| 44 | C WorldWide Group Holding A/S | 65,800 | 3,952,000 | 0.26% | ||
| 45 | TIAA CREF INVESTMENT MANAGEMENT LLC | 56,584 | 3,398,000 | 0.22% | ||
| 46 | BlackRock Group LTD | 51,867 | 3,116,000 | 0.20% | ||
| 47 | ALLIANCEBERNSTEIN L.P. | 51,100 | 3,069,000 | 0.20% | ||
| 48 | Artal Group S.A. | 50,000 | 3,003,000 | 0.19% | ||
| 49 | MORGAN STANLEY | 47,718 | 2,867,000 | 0.19% | ||
| 50 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 47,150 | 2,832,000 | 0.18% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
